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. Methods and materials Description of the cohort KTRs who underwent their first kidney transplant in West China Hospital between June 2020 and December 2020 were recruited as a prospective cohort to study the impacts of vitamin D supplementation on
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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cross-sectional study in Iranian adolescents (221 girls and 192 boys) aged 9–19 years showed that sUA was associated with BMD and bone mineral content at all sites, with higher BMD in adolescents with higher UA levels ( 25 ). In Chinese adolescents aged
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patients with PA were analyzed, respectively. Statistical analysis Statistical analyses were performed with SPSS version 23.0, GraphPad Prism 8.0, and SigmaPlot 14.0 (Systat Software Inc, Beijing, China). All the measurements were repeated three
Department of Endocrinology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Population in Beijing, China) for GIPR SNP rs10423928 using second-stage HapMap data ( ftp://ftp.ncbi.nlm.nih.gov/hapmap/ ). Both GLP-1 and GIP are incretins. Previously, we demonstrated a correlation between GLP-1 receptor gene ( GLP-1R ) polymorphisms and
College of Medicine, Chang Gung University, Taoyuan, Taiwan
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Department of Nephrology, Clinical Poison Center, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan
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Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan
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Department of Nephrology, China Medical University Hospital, Taichung, Taiwan
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Department of Nephrology, Clinical Poison Center, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan
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Department of Nephrology, Clinical Poison Center, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan
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Department of Nephrology, Clinical Poison Center, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan
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Department of Nephrology, Clinical Poison Center, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan
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Department of Nephrology, Clinical Poison Center, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan
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Department of Nephrology, Clinical Poison Center, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan
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for primary hyperparathyroidism in Chinese individuals . Scientific Reports 2017 7 4868 . ( https://doi.org/10.1038/s41598-017-05183-6 ) 39 Cruz DN & Perazella MA . Biochemical aberrations in a dialysis patient following parathyroidectomy
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Purpose
This study aims to investigate the associations of the systemic immune-inflammation index (SII) with bone mineral density (BMD) and osteoporosis in adult females from a nationally representative sample.
Methods
A cross-sectional study was performed among 4092 females aged ≥20 years from the National Health and Nutrition Examination Survey 2007–2010. Linear and logistic regressions were applied to explore the relationships of SII with BMD and the risk of osteoporosis, respectively.
Results
Linear regression analyses found that a doubling of SII levels was significantly correlated with a 1.39% (95% CI: 0.57%, 2.20%) decrease in total femur BMD, a 1.16% (95% CI: 0.31%, 2.00%) decrease in femur neck BMD, a 1.73% (95% CI: 0.78%, 2.66%) decrease in trochanter BMD, and a 1.35% (95% CI: 0.50%, 2.20%) decrease in intertrochanteric BMD among postmenopausal women, after adjusting for covariates. Logistic regression analyses showed that compared with postmenopausal women in the lowest SII quartile, those in the highest quartile had higher risks of osteoporosis in the total femur (odds ratio (OR) = 1.70, 95% CI: 1.04, 2.76), trochanter (OR = 1.86, 95% CI: 1.07, 3.38), intertrochanter (OR = 2.01, 95% CI: 1.05, 4.04) as well as overall osteoporosis (OR = 1.57, 95% CI: 1.04, 2.37). In contrast, there was no significant association between SII and BMD in premenopausal women.
Conclusions
SII levels were negatively associated with BMD levels in postmenopausal women but not in premenopausal women. Elevated SII levels could be a potential risk factor for osteoporosis in postmenopausal women.
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In this review, we discuss the definition, prevalence, and etiology of sporadic multiglandular disease (MGD), with an emphasis on its preoperative and intraoperative predictors. Primary hyperparathyroidism (PHPT) is the third-most common endocrine disorder, and multiglandular parathyroid disease (MGD) is a cause of PHPT. Hereditary MGD can be definitively diagnosed with detailed family history and genetic testing, whereas sporadic MGD presents a greater challenge in clinical practice, and parathyroidectomy for MGD is associated with a higher risk of surgical failure than single gland disease (SGD). Therefore, it is crucial to be able to predict the presence of sporadic MGD in a timely manner, either preoperatively or intraoperatively. Various predictive methods cannot accurately identify all cases of sporadic MGD, but they can greatly optimize the management of MGD diagnosis and treatment and optimize the cure rate. Future research will urge us to investigate more integrative predictive models as well as increase our understanding of MGD pathogenesis.
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Mainland China, published during 2000 to 2012 ( 52 ). While estimates were highly variable, as constituent individual studies differed by location, assay and season of sampling, the average prevalence of serum 25(OH)D < 25 nmol/L, using tabulated estimates
PhyMedExp, Université de Montpellier, INSERM, CNRS, Montpellier, France
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PhyMedExp, Université de Montpellier, INSERM, CNRS, Montpellier, France
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CIC INSERM 1411, Hôpital Gui de Chauliac, CHU Montpellier, Montpellier Cedex 5, France
Institut de Génomique Fonctionnelle, CNRS UMR 5203/INSERM U661/Université Montpellier, Montpellier, France
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CIC INSERM 1411, Hôpital Gui de Chauliac, CHU Montpellier, Montpellier Cedex 5, France
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Département de Biochimie, Hôpital Lapeyronie, CHU Montpellier, Montpellier, France
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Département d’Urgence et Post-Urgence Psychiatrique, Hôpital Lapeyronie, CHU Montpellier, Montpellier, France
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Département d’Urgence et Post-Urgence Psychiatrique, Hôpital Lapeyronie, CHU Montpellier, Montpellier, France
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Département Endocrinologie, Nutrition, Diabète, Equipe Nutrition, Diabète, CHU Montpellier, Montpellier, France
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), middle-aged male amateur runners ( 66 ) and postmenopausal women ( 39 ). Plasma irisin levels were associated with hip BMD in elderly Chinese men but not in women ( 67 ). In clinical studies, the inconsistent results concerning the relationship between
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in the following countries: four studies from Turkey, three from Spain, two from Denmark, five from the USA, two from Brazil, four from Italy and eight others from Iran, Korea, China, Thailand, England, Saudi Arabia, Sri Lanka, and Germany. The
