Division of Biomedical Information Analysis, Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Yahaba, Japan
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Faculty of Health Science, Bukkyo University, Kyoto, Japan
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KNDy gene expression in the mature female offspring The ARC KNDy gene expression was identified in the E2-primed OVX mature offspring ( Figs. 4A and B ). The total numbers of ARC Kiss1 -, Tac3 -, and Pdyn - expressing cells in the UN offspring
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Université Paris Cité, Faculté de Santé, UFR de Médecine, Paris, France
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Université Paris Cité, Faculté de Santé, UFR de Médecine, Paris, France
Inserm UMR1185, Le Kremlin Bicetre, Paris, France
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Inserm UMR1185, Le Kremlin Bicetre, Paris, France
Paris-Saclay University, Paris, France
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cells, and perhaps, by extension, for future fertility ( 3 , 4 , 5 , 6 ). Anti-Müllerian hormone (AMH) and Inhibin B are reliable biomarkers reflecting Sertoli cells function, while testosterone is an index of Leydig cell activation. Boys with CHH
Molecular Reproductive Research Group, Department of Translational Medicine, Lund University, Malmö, Sweden
Institute of Molecular Biology and Biotechnology, FORTH, Heraklion, Greece
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Reproductive Medicine Centre, Skåne University Hospital Malmö, Malmö, Sweden
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Reproductive Medicine Centre, Skåne University Hospital Malmö, Malmö, Sweden
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immune responses and susceptibility to autoimmunity and inflammatory diseases. B-cell activating factor (BAFF) also known as tumor necrosis factor (TNF) ligand superfamily member 13B is a cytokine of the TNF family that is causally linked to the
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was evaluated. To clarify its role, NEDD4L was overexpressed in KGN cells. qRT-PCR and western blotting were used to confirm the effectiveness of NEDD4L-OE ( Fig. 2A and B ). The CCK-8 assay and FDA staining were used to determine the cell viability
Fujian Maternal-Fetal Clinical Medicine Research Center, Fuzhou, China
Fujian Key Laboratory of Prenatal Diagnosis and Birth Defect, Fuzhou, China
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Fujian Maternal-Fetal Clinical Medicine Research Center, Fuzhou, China
Fujian Key Laboratory of Prenatal Diagnosis and Birth Defect, Fuzhou, China
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of our experiments. The cells or tissues to be analyzed were lysed using Lysis buffer (Beijing Biocytogen, P0013B) at 4°C for 30 min, and the total protein was obtained by sonication using an ultrasonic homogenizer. After measuring the protein
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Center of Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
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isolation from skin biopsies and somatic cell reprogramming Skin biopsies from five donors were cultured to establish fibroblast cell lines with 47,XXY and 46,XY karyotypes ( Table 1 , Fig. 1A ), as assessed by KaryoStat assay ( Fig. 1B and C ). The
Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark
Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
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Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
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Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
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Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Gynaecology and Obstetrics, Aarhus University Hospital, Aarhus, Denmark
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Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Endocrinology, Aarhus University Hospital, Aarhus, Denmark
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Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark
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cell omics (A) or sectioned, stained, imaged and barcoded prior to sequencing for spatial RNA expression (B). If possible, clinical measurements should be obtained at the same time for the same individuals (C). Multi-omics and clinical measurements can
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inhibin B, but with high interpersonal variation: a cross-sectional study of the Sertoli cell hormones in 615 community-dwelling men . PLoS One 2013 8 e70967 . ( https://doi.org/10.1371/journal.pone.0070967 ) 22 van Brakel J de Muinck Keizer
Key Laboratory of Animal Embryo and Development Engineering of Autonomous Region Universities, Inner Mongolia Agricultural University, Hohhot, PR China
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Key Laboratory of Animal Embryo and Development Engineering of Autonomous Region Universities, Inner Mongolia Agricultural University, Hohhot, PR China
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Key Laboratory of Animal Embryo and Development Engineering of Autonomous Region Universities, Inner Mongolia Agricultural University, Hohhot, PR China
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National Center of Technology Innovation for Dairy Industry, Hohhot, PR China
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Key Laboratory of Animal Embryo and Development Engineering of Autonomous Region Universities, Inner Mongolia Agricultural University, Hohhot, PR China
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Key Laboratory of Animal Embryo and Development Engineering of Autonomous Region Universities, Inner Mongolia Agricultural University, Hohhot, PR China
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Key Laboratory of Animal Embryo and Development Engineering of Autonomous Region Universities, Inner Mongolia Agricultural University, Hohhot, PR China
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Introduction Gap junctions, a type of cell membrane channel that exists in close contact sites between adjacent cells, allow the transfer and communication of ions and metabolites between cells, which is crucial for maintaining the normal
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axis at level of ovary) Increased incidence of autoimmunity ↑LH, FSH to GnRH stimulation 47,XXY Tall stature (onset may be in mid-childhood) Mini-puberty-contradictory results Childhood-↑INH B; Accelerated germ cell loss at