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Eleftherios E Deiktakis
Eleftherios E Deiktakis
Laboratory of Clinical Chemistry, School of Medicine, University of Crete, Heraklion, Greece
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Eleftheria Ieronymaki
Eleftheria Ieronymaki
Laboratory of Clinical Chemistry, School of Medicine, University of Crete, Heraklion, Greece
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Peter Zarén
Peter Zarén
Department of Translational Medicine, Lund University, Malmö, Sweden
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Agnes Hagsund
Agnes Hagsund
Department of Translational Medicine, Lund University, Malmö, Sweden
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Elin Wirestrand
Elin Wirestrand
Department of Translational Medicine, Lund University, Malmö, Sweden
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Johan Malm
Johan Malm
Department of Translational Medicine, Lund University, Malmö, Sweden
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Christos Tsatsanis
Christos Tsatsanis
Laboratory of Clinical Chemistry, School of Medicine, University of Crete, Heraklion, Greece
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Ilpo T Huhtaniemi
Ilpo T Huhtaniemi
Department of Translational Medicine, Lund University, Malmö, Sweden
Imperial College London, Institute of Reproductive and Developmental Biology, London, UK
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Imperial College London, Institute of Reproductive and Developmental Biology, London, UK
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Aleksander Giwercman
Aleksander Giwercman
Department of Translational Medicine, Lund University, Malmö, Sweden
Malmö University Hospital, Reproductive Medicine Center, Malmö, Sweden
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Malmö University Hospital, Reproductive Medicine Center, Malmö, Sweden
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Yvonne Lundberg Giwercman
Yvonne Lundberg Giwercman
Department of Translational Medicine, Lund University, Malmö, Sweden
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spermatozoa. Possibly, and perhaps even likely, prostate cancer cells utilize the same process for growth and progression to an incurable disease, but in healthy men, we do not find evidence for this to be the situation. The response of inhibin B levels to
Anna Gorbacheva
Anna Gorbacheva
Endocrinology Research Center, Moscow, Russian Federation
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Anna Eremkina
Anna Eremkina
Endocrinology Research Center, Moscow, Russian Federation
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Daria Goliusova
Daria Goliusova
Endocrinology Research Center, Moscow, Russian Federation
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Julia Krupinova
Julia Krupinova
Endocrinology Research Center, Moscow, Russian Federation
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Natalia Mokrysheva
Natalia Mokrysheva
Endocrinology Research Center, Moscow, Russian Federation
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proliferation of osteoid cells, but the experiments proving that Cdkn1b is indeed involved in menin function in bone are missing. Menin and homeobox genes The nature of interaction between menin and homeobox genes (Hox genes, highly concerned DNA
Hélène Singeisen
Hélène Singeisen
Department of Internal Medicine, Endocrinology, Cantonal Hospital Thurgau, Münsterlingen, Switzerland
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Mariko Melanie Renzulli
Mariko Melanie Renzulli
Institute of Radiology, Cantonal Hospital Thurgau, Frauenfeld, Switzerland
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Vojtech Pavlicek
Vojtech Pavlicek
Department of Internal Medicine, Endocrinology, Cantonal Hospital Thurgau, Münsterlingen, Switzerland
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Pascal Probst
Pascal Probst
Department of Surgery, Cantonal Hospital Thurgau, Frauenfeld, Switzerland
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Fabian Hauswirth
Fabian Hauswirth
Department of Surgery, Cantonal Hospital Thurgau, Münsterlingen, Switzerland
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Markus K Muller
Markus K Muller
Department of Surgery, Cantonal Hospital Thurgau, Frauenfeld, Switzerland
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Magdalene Adamczyk
Magdalene Adamczyk
Department of Pathology and Molecular Pathology, University Hospital Zurich and University of Zurich, Zurich, Switzerland
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Achim Weber
Achim Weber
Department of Pathology and Molecular Pathology, University Hospital Zurich and University of Zurich, Zurich, Switzerland
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Reto Martin Kaderli
Reto Martin Kaderli
Department of Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Bern, Switzerland
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Pietro Renzulli
Pietro Renzulli
Department of Surgery, Cantonal Hospital Thurgau, Münsterlingen, Switzerland
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the cyclin-dependent kinase (CDK) inhibitor 1b gene ( CDKN1B ), a gene coding for the nuclear protein p27 kip1 , commonly referred to as p27 or KIP1. It is a putative tumor suppressor gene regulating cell cycle progression, notably the progression from
Anela Blažević
Anela Blažević
Department of Internal Medicine, Section Endocrinology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands
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Anand M Iyer
Anand M Iyer
Department of Internal Medicine, Section Endocrinology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands
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Marie-Louise F van Velthuysen
Marie-Louise F van Velthuysen
Department of Pathology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands
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Johannes Hofland
Johannes Hofland
Department of Internal Medicine, Section Endocrinology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands
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Peter M van Koestveld
Peter M van Koestveld
Department of Internal Medicine, Section Endocrinology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands
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Gaston J H Franssen
Gaston J H Franssen
Department of Surgery, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands
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Richard A Feelders
Richard A Feelders
Department of Internal Medicine, Section Endocrinology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands
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Marina Zajec
Marina Zajec
Laboratory of Neuro-Oncology/Clinical & Cancer Proteomics, Department of Neurology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands
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Theo M Luider
Theo M Luider
Laboratory of Neuro-Oncology/Clinical & Cancer Proteomics, Department of Neurology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands
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Wouter W de Herder
Wouter W de Herder
Department of Internal Medicine, Section Endocrinology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands
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Leo J Hofland
Leo J Hofland
Department of Internal Medicine, Section Endocrinology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands
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neuroendocrine tumors. Next, we compared patients with and without mesenteric fibrosis (MF vs non-MF) ( Fig. 2B ). In primary tumors, patients with MF had higher MAO-A staining score in tumor cells (median 33.5 I/A vs 25.8 I/A in non-MF, P = 0.03). On
Enrique Pedernera
Enrique Pedernera
Universidad Nacional Autónoma de México, Facultad de Medicina, Departamento de Embriología y Genética, Ciudad de México, México
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Flavia Morales-Vásquez
Flavia Morales-Vásquez
Instituto Nacional de Cancerología, Ciudad de México, México
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María J Gómora
María J Gómora
Universidad Nacional Autónoma de México, Facultad de Medicina, Departamento de Embriología y Genética, Ciudad de México, México
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Miguel A Almaraz
Miguel A Almaraz
Universidad Nacional Autónoma de México, Facultad de Medicina, Departamento de Embriología y Genética, Ciudad de México, México
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Esteban Mena
Esteban Mena
Universidad Nacional Autónoma de México, Facultad de Medicina, Secretaría General, Ciudad de México, México
Universidad La Salle, Posgrado de la Facultad de Ciencias Químicas, Ciudad de México, México
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Universidad La Salle, Posgrado de la Facultad de Ciencias Químicas, Ciudad de México, México
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Delia Pérez-Montiel
Delia Pérez-Montiel
Instituto Nacional de Cancerología, Ciudad de México, México
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Elizabeth Rendon
Elizabeth Rendon
Hospital Militar de Especialidades de la Mujer y Neonatología. Ciudad de México, México
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Horacio López-Basave
Horacio López-Basave
Instituto Nacional de Cancerología, Ciudad de México, México
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Juan Maldonado-Cubas
Juan Maldonado-Cubas
Universidad La Salle, Posgrado de la Facultad de Ciencias Químicas, Ciudad de México, México
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Carmen Méndez
Carmen Méndez
Universidad Nacional Autónoma de México, Facultad de Medicina, Departamento de Embriología y Genética, Ciudad de México, México
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four histological types: serous, endometrioid, mucinous, and clear cells. Serous tumors are the most frequent and are classified as: borderline tumor (BT), low-grade serous carcinoma (LGSC), and high-grade serous carcinoma (HGSC). Endometrioid
Vita Birzniece
Vita Birzniece
School of Medicine, Western Sydney University, New South Wales, Australia
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Garvan Institute of Medical Research, New South Wales, Australia
School of Medical Sciences, University of New South Wales, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Garvan Institute of Medical Research, New South Wales, Australia
School of Medical Sciences, University of New South Wales, New South Wales, Australia
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Teresa Lam
Teresa Lam
School of Medicine, Western Sydney University, New South Wales, Australia
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Department of Diabetes and Endocrinology, Westmead Hospital, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Department of Diabetes and Endocrinology, Westmead Hospital, New South Wales, Australia
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Mark McLean
Mark McLean
School of Medicine, Western Sydney University, New South Wales, Australia
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
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Navneeta Reddy
Navneeta Reddy
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
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Haleh Shahidipour
Haleh Shahidipour
School of Medicine, Western Sydney University, New South Wales, Australia
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
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Amy Hayden
Amy Hayden
School of Medicine, Western Sydney University, New South Wales, Australia
Faculty of Medicine, Health and Human Sciences, Macquarie University, New South Wales, Australia
Crown Princess Mary Cancer Centre, Westmead Hospital, New South Wales, Australia
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Faculty of Medicine, Health and Human Sciences, Macquarie University, New South Wales, Australia
Crown Princess Mary Cancer Centre, Westmead Hospital, New South Wales, Australia
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Howard Gurney
Howard Gurney
Crown Princess Mary Cancer Centre, Westmead Hospital, New South Wales, Australia
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Glenn Stone
Glenn Stone
School of Computing, Engineering and Mathematics, Western Sydney University, New South Wales, Australia
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Rikke Hjortebjerg
Rikke Hjortebjerg
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
Steno Diabetes Center Odense, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
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Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
Steno Diabetes Center Odense, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
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Jan Frystyk
Jan Frystyk
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
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Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
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inhibition involves suppression of the IGF-I receptor signalling pathway in human pancreatic cancer cells . BMC Cancer 2013 13 235. ( https://doi.org/10.1186/1471-2407-13-235 ) 14 Clements A Gao B Yeap SHO Wong MKY Ali SS Gurney H . Metformin
Malgorzata Fuksiewicz
Malgorzata Fuksiewicz
Laboratory of Tumor Markers, Department of Pathology and Laboratory Diagnostics, The Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland
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Maria Kowalska
Maria Kowalska
Laboratory of Tumor Markers, Department of Pathology and Laboratory Diagnostics, The Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland
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Agnieszka Kolasinska-Cwikla
Agnieszka Kolasinska-Cwikla
Department of Oncology and Radiotherapy, The Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland
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Beata Kotowicz
Beata Kotowicz
Laboratory of Tumor Markers, Department of Pathology and Laboratory Diagnostics, The Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland
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approximately 24 h. NSE is found in the cytoplasm of neurons and neuroendocrine cells. Mechanisms leading to the destruction of these cells cause an increase in NSE concentration in body fluids. Hence, numerous studies have evaluated its usefulness in predicting
Xiaoya Zheng
Xiaoya Zheng
Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Shanshan Yu
Shanshan Yu
Pathology Department, Chongqing Medical University, Chongqing, China
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Jian Long
Jian Long
Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Qiang Wei
Qiang Wei
Prevention of Disease Department, Chongqing Jiulongpo District Hospital of Traditional Chinese Medicine, Chongqing, China
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Liping Liu
Liping Liu
Department of Ultrasound, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Chun Liu
Chun Liu
Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Wei Ren
Wei Ren
Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Representative histological figures of diffuse sclerosing variant of papillary thyroid carcinoma (DSVPTC) and thyroid diffuse large B-cell lymphoma (DLBCL). (A) Histopathology of DSVPTC showing the carcinoma had numerous psammoma bodies, papillary structures and
Arnaud Lagarde
Arnaud Lagarde
Aix Marseille Univ, APHM, INSERM, MMG, Laboratory of Molecular Biology Hospital La Conception, Marseille, France
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Grégory Mougel
Grégory Mougel
Aix Marseille Univ, APHM, INSERM, MMG, Laboratory of Molecular Biology Hospital La Conception, Marseille, France
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Lucie Coppin
Lucie Coppin
Univ. Lille, CNRS, Inserm, CHU Lille, UMR9020-U1277 – CANTHER – Cancer – Heterogeneity Plasticity and Resistance to Therapies, Lille, France
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Magalie Haissaguerre
Magalie Haissaguerre
Service d’Endocrinologie, Centre Hospitalier Universitaire, Hôpital du Haut Levêque, Pessac, France
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Lauriane Le Collen
Lauriane Le Collen
Endocrinology, Diabetology and Nutrition Unit, University Hospital of Reims, Reims, France
Inserm/CNRS UMR 1283/8199, Pasteur Institute of Lille, EGID, Lille, France
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Inserm/CNRS UMR 1283/8199, Pasteur Institute of Lille, EGID, Lille, France
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Amira Mohamed
Amira Mohamed
Laboratory of Molecular Biology, Hospital La Conception, APHM, Marseille, France
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Marc Klein
Marc Klein
Service Endocrinologie, CHU de Nancy, Hôpital de Brabois, Vandoeuvre-lès-Nancy, France
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Marie-Françoise Odou
Marie-Françoise Odou
CHU Lille, Service de Biochimie et Biologie Moléculaire ‘Hormonologie, Métabolisme-Nutrition, Oncologie’, Lille, France
Univ. Lille, Inserm, CHU Lille, U1286 – Infinite – Institute for Translational Research in Inflammation, Lille, France
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Univ. Lille, Inserm, CHU Lille, U1286 – Infinite – Institute for Translational Research in Inflammation, Lille, France
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Antoine Tabarin
Antoine Tabarin
Service d’Endocrinologie, Centre Hospitalier Universitaire, Hôpital du Haut Levêque, Pessac, France
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Hedia Brixi
Hedia Brixi
Department of Gastroenterology and Digestive Oncology, Reims University Hospital, Reims, France
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Thomas Cuny
Thomas Cuny
Aix Marseille Univ, APHM, INSERM, MMG, Department of Endocrinology, Hospital La Conception, Marseille, France
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Brigitte Delemer
Brigitte Delemer
Endocrinology, Diabetology and Nutrition Unit, University Hospital of Reims, Reims, France
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Anne Barlier
Anne Barlier
Aix Marseille Univ, APHM, INSERM, MMG, Laboratory of Molecular Biology Hospital La Conception, Marseille, France
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Pauline Romanet
Pauline Romanet
Aix Marseille Univ, APHM, INSERM, MMG, Laboratory of Molecular Biology Hospital La Conception, Marseille, France
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cases. Mosaicism has been described in several inherited tumor syndromes and corresponds to the spontaneous acquisition of a genetic variant during cell division during post-zygotic embryonic development ( 7 , 8 , 9 , 10 , 11 ). Mosaicism thus
Mark J C van Treijen
Mark J C van Treijen
Department of Endocrine Oncology, University Medical Center Utrecht, Utrecht, The Netherlands
Center for Neuroendocrine Tumors, ENETS Center of Excellence, Netherlands Cancer Institute, University Medical Center Utrecht, Utrecht, The Netherlands
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Center for Neuroendocrine Tumors, ENETS Center of Excellence, Netherlands Cancer Institute, University Medical Center Utrecht, Utrecht, The Netherlands
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Catharina M Korse
Catharina M Korse
Center for Neuroendocrine Tumors, ENETS Center of Excellence, Netherlands Cancer Institute, University Medical Center Utrecht, Utrecht, The Netherlands
Department of Clinical Chemistry, The Netherlands Cancer Institute, Amsterdam, The Netherlands
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Department of Clinical Chemistry, The Netherlands Cancer Institute, Amsterdam, The Netherlands
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Wieke H Verbeek
Wieke H Verbeek
Center for Neuroendocrine Tumors, ENETS Center of Excellence, Netherlands Cancer Institute, University Medical Center Utrecht, Utrecht, The Netherlands
Department of Gastroenterology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
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Department of Gastroenterology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
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Margot E T Tesselaar
Margot E T Tesselaar
Center for Neuroendocrine Tumors, ENETS Center of Excellence, Netherlands Cancer Institute, University Medical Center Utrecht, Utrecht, The Netherlands
Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
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Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
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Gerlof D Valk
Gerlof D Valk
Department of Endocrine Oncology, University Medical Center Utrecht, Utrecht, The Netherlands
Center for Neuroendocrine Tumors, ENETS Center of Excellence, Netherlands Cancer Institute, University Medical Center Utrecht, Utrecht, The Netherlands
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Center for Neuroendocrine Tumors, ENETS Center of Excellence, Netherlands Cancer Institute, University Medical Center Utrecht, Utrecht, The Netherlands
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Introduction Neuroendocrine tumors (NETs) are malignant neoplasms originating from neuroendocrine cells and can occur throughout the body. Gastroenteropancreatic NETs (GEPNETs) are the most prevalent subgroup. Both incidence and survival have
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