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control. Higher pregestational BMI and fasting PG levels in OGTT, earlier GDM diagnosis and metformin treatment initiation, and hypertension increased the risk of metformin monotherapy failure, although only the BMI value, fasting PG levels in OGTT and
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Department of Internal Medicine III, University Hospital Carl Gustav Carus Dresden, Dresden, Germany
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Comprehensive Heart Failure Center, Würzburg, Germany
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intervals within the delivery time of the osmotic minipumps (42 days) for all treatment groups. At the time of treatment initiation, all treatment groups (starting at different time points) had comparable body weights (567 ± 48 g for group 1, 576 ± 6 g for
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
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Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Parameters calculated from data recorded from 8:00 h at the day of prednisolone/prednisolone placebo treatment initiation until second magnetic resonance spectroscopy or the night before experimental day #2 whichever came first. b Welch two-sample t test. CV
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Department of Endocrinology, Royal Prince Alfred Hospital, Sydney, NSW, Australia
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Department of Renal Medicine, St George Hospital, Sydney, NSW, Australia
Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, Australia
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prior to treatment initiation with SGLT2 inhibitors and to correct hypovolemia (particularly in elderly patients, in patients with impaired kidney function or low systolic blood pressure and in patients receiving diuretics) ( 69 , 70 , 71 , 72 ). In