Jian Gong
Jian Gong
School of Basic Medicine, Hubei University of Chinese Medicine, Wuhan, China
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Yinjuan Lv
Yinjuan Lv
School of Basic Medicine, Hubei University of Chinese Medicine, Wuhan, China
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Yuhao Meng
Yuhao Meng
Hubei University of Chinese Medicine, Wuhan, China
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Weiheng Zhang
Weiheng Zhang
Hubei University of Chinese Medicine, Wuhan, China
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Xiaocui Jiang
Xiaocui Jiang
Hubei University of Chinese Medicine, Wuhan, China
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Min Xiao
Min Xiao
Laboratory Animal Center, Hubei University of Chinese Medicine, Wuhan, China
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Introduction Prenatal stress (PS) is the body's response when various internal and external factors stimulate a woman during pregnancy ( 1 ). Studies have shown that when women are exposed to stressful events during pregnancy, they can disrupt
Xinyuan Zhang
Xinyuan Zhang
Laboratory of Genetic Disease and Perinatal Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China
School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, Sichuan, China
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School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, Sichuan, China
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Suiyan Li
Suiyan Li
School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, Sichuan, China
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Hongwei Liu
Hongwei Liu
Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China
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Huai Bai
Huai Bai
Laboratory of Genetic Disease and Perinatal Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China
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Qingqing Liu
Qingqing Liu
Laboratory of Genetic Disease and Perinatal Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China
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Chunyi Yang
Chunyi Yang
Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China
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Ping Fan
Ping Fan
Laboratory of Genetic Disease and Perinatal Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China
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resistance, heightened oxidative stress, low-grade chronic inflammation, dyslipidemia, increased risks of complications during pregnancy, type 2 diabetes, cardiocerebrovascular disease, anxiety and depression, obstructive sleep apnea, and endometrial cancer
Yan-yu Zhang
Yan-yu Zhang
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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Xian Zhang
Xian Zhang
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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Shao-yang Bu
Shao-yang Bu
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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Wei-wei Zhang
Wei-wei Zhang
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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Tian-xiu Li
Tian-xiu Li
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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De-cai Zheng
De-cai Zheng
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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Ze-xiang Huang
Ze-xiang Huang
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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Qian Wang
Qian Wang
Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China
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the ventral (Hv) ( 22 ). The brain is regarded as the organ where kisspeptin genes primarily act, and the habenula mainly regulates circadian rhythm and stress response ( 23 ). The sexually dimorphic distribution of kiss -positive cells in the brain
Hong Tang
Hong Tang
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Xiaomei Jiang
Xiaomei Jiang
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Yu Hua
Yu Hua
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Heyue Li
Heyue Li
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Chunlan Zhu
Chunlan Zhu
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Xiaobai Hao
Xiaobai Hao
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Minhui Yi
Minhui Yi
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Linxia Li
Linxia Li
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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-resistant hyperinsulinism and androgen alter the function of granulosa cells (GCs) ( 6 , 7 ). GCs play a key role in the maturation and ovulation of oocytes. Recently, studies have reported that oxidative stress and oxidative stress-induced cell death in GCs are associated
Salma R Ali
Salma R Ali
Developmental Endocrinology Research Group, Royal Hospital for Children, University of Glasgow, Glasgow, UK
Office for Rare Conditions, University of Glasgow, Glasgow, UK
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Office for Rare Conditions, University of Glasgow, Glasgow, UK
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Melissa Gardner
Melissa Gardner
Susan B Meister Child Health Evaluation and Research Center, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA
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Yiqiao Xin
Yiqiao Xin
Health Economics and Health Technology Assessment, Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK
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Stuart O’Toole
Stuart O’Toole
Department of Paediatric Surgery, Royal Hospital for Children, Glasgow, UK
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Martyn Flett
Martyn Flett
Department of Paediatric Surgery, Royal Hospital for Children, Glasgow, UK
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Boma Lee
Boma Lee
Department of Paediatric Surgery, Royal Hospital for Children, Glasgow, UK
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Mairi Steven
Mairi Steven
Department of Paediatric Surgery, Royal Hospital for Children, Glasgow, UK
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David E Sandberg
David E Sandberg
Susan B Meister Child Health Evaluation and Research Center, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA
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S Faisal Ahmed
S Faisal Ahmed
Developmental Endocrinology Research Group, Royal Hospital for Children, University of Glasgow, Glasgow, UK
Office for Rare Conditions, University of Glasgow, Glasgow, UK
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Office for Rare Conditions, University of Glasgow, Glasgow, UK
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associated with adverse psychosocial and psychosexual outcomes ( 2 , 3 , 4 , 5 , 6 ). Studies have shown that a subset of parents of children with such conditions can experience high levels of depression, anxiety, and stress related to concerns regarding
Xiuhua Liao
Xiuhua Liao
Center of Reproductive Medicine, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China
Fujian Maternal-Fetal Clinical Medicine Research Center, Fuzhou, China
Fujian Key Laboratory of Prenatal Diagnosis and Birth Defect, Fuzhou, China
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Fujian Maternal-Fetal Clinical Medicine Research Center, Fuzhou, China
Fujian Key Laboratory of Prenatal Diagnosis and Birth Defect, Fuzhou, China
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Suqin Zhu
Suqin Zhu
Center of Reproductive Medicine, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China
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Shumin Qiu
Shumin Qiu
Center of Reproductive Medicine, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China
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Hua Cao
Hua Cao
Center of Reproductive Medicine, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China
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Wenwen Jiang
Wenwen Jiang
Center of Reproductive Medicine, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China
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Huiling Xu
Huiling Xu
Center of Reproductive Medicine, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China
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Yan Sun
Yan Sun
Center of Reproductive Medicine, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China
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Beihong Zheng
Beihong Zheng
Center of Reproductive Medicine, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China
Fujian Maternal-Fetal Clinical Medicine Research Center, Fuzhou, China
Fujian Key Laboratory of Prenatal Diagnosis and Birth Defect, Fuzhou, China
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Fujian Maternal-Fetal Clinical Medicine Research Center, Fuzhou, China
Fujian Key Laboratory of Prenatal Diagnosis and Birth Defect, Fuzhou, China
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mitochondrial morphology, interorganelle Ca 2+ transport ( 12 , 13 ), lipid transportation, and participates in ER stress ( 14 ) and mitophagy. It is a key mediator of mitochondrial fusion, and its expression is decreased in PCOS patients ( 15 ). Mfn2 has been
Srdjan Pandurevic
Srdjan Pandurevic
Division of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Ilaria Mancini
Ilaria Mancini
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
Unit of Gynecology and Obstetrics, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy
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Unit of Gynecology and Obstetrics, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy
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Dimitri Mitselman
Dimitri Mitselman
Division of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Matteo Magagnoli
Matteo Magagnoli
Division of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Rita Teglia
Rita Teglia
Division of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Roberta Fazzeri
Roberta Fazzeri
Division of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Paola Dionese
Paola Dionese
Division of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Carolina Cecchetti
Carolina Cecchetti
Division of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Massimiliamo Caprio
Massimiliamo Caprio
Department of Human Sciences and Quality of Life Promotion, San Raffaele Roma Open University, Rome, Italy
Laboratory of Cardiovascular Endocrinology, IRCCS San Raffaele, Rome, Italy
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Laboratory of Cardiovascular Endocrinology, IRCCS San Raffaele, Rome, Italy
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Costanzo Moretti
Costanzo Moretti
Department of Systems Medicine, Unit of Endocrinology, University of Rome Tor Vergata, Rome, Italy
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Justyna Sicinska
Justyna Sicinska
Dermatology Clinic of CSK MSWiA Hospital, Warsaw, Poland
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Alessandro Agostini
Alessandro Agostini
Department of Experimental, Diagnostic, and Specialty Medicine, University of Bologna, Bologna, Italy
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Domenica Gazineo
Domenica Gazineo
Teaching Hospital, S. Orsola Hospital, Bologna, Italy
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Lea Godino
Lea Godino
Teaching Hospital, S. Orsola Hospital, Bologna, Italy
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Ignacio Sajoux
Ignacio Sajoux
Epigenomics in Endocrinology and Nutrition Group, Instituto de Investigacion Sanitaria (IDIS), Complejo Hospitalario Universitario de Santiago (CHUS/SERGAS), Spain
Medical Department Pronokal Group, Barcelona, Spain
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Medical Department Pronokal Group, Barcelona, Spain
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Flaminia Fanelli
Flaminia Fanelli
Division of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Cristina M Meriggiola
Cristina M Meriggiola
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
Unit of Gynecology and Obstetrics, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy
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Unit of Gynecology and Obstetrics, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy
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Uberto Pagotto
Uberto Pagotto
Division of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Alessandra Gambineri
Alessandra Gambineri
Division of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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, some adipokines, and oxidative stress have been described ( 49 , 50 ). Interestingly, although both the body weight and body fat decreased during the study period in the experimental group, waist circumference significantly decreased at the end of the
Sophie van Rijn
Sophie van Rijn
Clinical Neurodevelopmental Sciences, Leiden University, Wassenaarseweg, Leiden, The Netherlands
TRIXY Center of Expertise, Leiden University Treatment and Expertise Centre (LUBEC), Sandifortdreef, Leiden, The Netherlands
Leiden Institute for Brain and Cognition, Leiden University, Wassenaarseweg, Leiden, The Netherlands
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TRIXY Center of Expertise, Leiden University Treatment and Expertise Centre (LUBEC), Sandifortdreef, Leiden, The Netherlands
Leiden Institute for Brain and Cognition, Leiden University, Wassenaarseweg, Leiden, The Netherlands
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Kimberly Kuiper
Kimberly Kuiper
Clinical Neurodevelopmental Sciences, Leiden University, Wassenaarseweg, Leiden, The Netherlands
TRIXY Center of Expertise, Leiden University Treatment and Expertise Centre (LUBEC), Sandifortdreef, Leiden, The Netherlands
Leiden Institute for Brain and Cognition, Leiden University, Wassenaarseweg, Leiden, The Netherlands
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TRIXY Center of Expertise, Leiden University Treatment and Expertise Centre (LUBEC), Sandifortdreef, Leiden, The Netherlands
Leiden Institute for Brain and Cognition, Leiden University, Wassenaarseweg, Leiden, The Netherlands
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Nienke Bouw
Nienke Bouw
Clinical Neurodevelopmental Sciences, Leiden University, Wassenaarseweg, Leiden, The Netherlands
TRIXY Center of Expertise, Leiden University Treatment and Expertise Centre (LUBEC), Sandifortdreef, Leiden, The Netherlands
Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC, Sophia Children’s Hospital, Dr. Molewaterplein, Rotterdam, The Netherlands
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TRIXY Center of Expertise, Leiden University Treatment and Expertise Centre (LUBEC), Sandifortdreef, Leiden, The Netherlands
Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC, Sophia Children’s Hospital, Dr. Molewaterplein, Rotterdam, The Netherlands
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Evelien Urbanus
Evelien Urbanus
Clinical Neurodevelopmental Sciences, Leiden University, Wassenaarseweg, Leiden, The Netherlands
TRIXY Center of Expertise, Leiden University Treatment and Expertise Centre (LUBEC), Sandifortdreef, Leiden, The Netherlands
Department of Clinical, Neuro, and Developmental Psychology, Vrije Universiteit Amsterdam, Van der Boechorststraat, Amsterdam, The Netherlands
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TRIXY Center of Expertise, Leiden University Treatment and Expertise Centre (LUBEC), Sandifortdreef, Leiden, The Netherlands
Department of Clinical, Neuro, and Developmental Psychology, Vrije Universiteit Amsterdam, Van der Boechorststraat, Amsterdam, The Netherlands
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Hanna Swaab
Hanna Swaab
Clinical Neurodevelopmental Sciences, Leiden University, Wassenaarseweg, Leiden, The Netherlands
TRIXY Center of Expertise, Leiden University Treatment and Expertise Centre (LUBEC), Sandifortdreef, Leiden, The Netherlands
Leiden Institute for Brain and Cognition, Leiden University, Wassenaarseweg, Leiden, The Netherlands
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TRIXY Center of Expertise, Leiden University Treatment and Expertise Centre (LUBEC), Sandifortdreef, Leiden, The Netherlands
Leiden Institute for Brain and Cognition, Leiden University, Wassenaarseweg, Leiden, The Netherlands
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stress the relevance of structural and pragmatic language on later behavioral outcomes. Poorer pragmatic and structural language abilities at baseline were predictive of more attention-deficit problems, more pervasive developmental problems, and more
Theodoros Karampitsakos
Theodoros Karampitsakos
Third Department of Obstetrics and Gynecology, ATTIKON University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
Unit of Endocrinology, Diabetes Mellitus and Metabolism, ARETAIEION University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Unit of Endocrinology, Diabetes Mellitus and Metabolism, ARETAIEION University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Fotini Kanouta
Fotini Kanouta
Unit of Endocrinology, Diabetes Mellitus and Metabolism, First Department of Obstetrics and Gynecology, ALEXANDRA University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
Unit of Endocrinology, Diabetes Mellitus and Metabolism, ARETAIEION University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Unit of Endocrinology, Diabetes Mellitus and Metabolism, ARETAIEION University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Christos Chatzakis
Christos Chatzakis
Second Department of Obstetrics and Gynecology, IPPOKRATEIO General Hospital of Thessaloniki, Aristotle, University of Thessaloniki, Athens, Greece
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Vassilios Bakoulas
Vassilios Bakoulas
Athens, Greece
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Alexandros Gryparis
Alexandros Gryparis
Department of Speech and Language Therapy, University of Ioannina, Ioannina, Greece
Unit of Endocrinology, Diabetes Mellitus and Metabolism, ARETAIEION University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Unit of Endocrinology, Diabetes Mellitus and Metabolism, ARETAIEION University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Petros Drakakis
Petros Drakakis
Third Department of Obstetrics and Gynecology, ATTIKON University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Djuro Macut
Djuro Macut
Department of Endocrinology, Diabetes and Diseases of Metabolism, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Unit of Endocrinology, Diabetes Mellitus and Metabolism, ARETAIEION University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Unit of Endocrinology, Diabetes Mellitus and Metabolism, ARETAIEION University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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George Mastorakos
George Mastorakos
Unit of Endocrinology, Diabetes Mellitus and Metabolism, ARETAIEION University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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has been associated with triggering term (normally towards the end of the third trimester) or pre-term (it occurs earlier, often related to maternal or fetal stress) labor ( 17 , 18 , 19 , 20 ). In fetal lambs, exogenous administration of CRH or GCs
Pamela Stratton
Pamela Stratton
Office of the Clinical Director, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
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Neelam Giri
Neelam Giri
Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
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Sonia Bhala
Sonia Bhala
Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
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Martha M Sklavos
Martha M Sklavos
Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA
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Blanche P Alter
Blanche P Alter
Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
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Sharon A Savage
Sharon A Savage
Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
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Ligia A Pinto
Ligia A Pinto
Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA
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levels ( 11 , 35 ). Notably, fertility defects in males with FA appear due to high replicative stress and mutational load both during organogenesis and spermatogenesis ( 36 ). In contrast, this study showed that fertility does not appear to be affected
