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selection bias, incomplete data for outcome analysis and local treatment traditions should restrict any reader from generalizing our data to a wider perspective. Clearly, a prospective study design and/or a matched control group would allow for a more
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Department of Florey Institute, University of Melbourne, Parkville, Victoria, Australia
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significantly associated with cognitive decline on the Mini-Mental State Examination (MMSE) in older men after 2 years and 5 years ( 8 ). In a prospective randomized controlled trial in 106 hypogonadal men, exogenous androgen add-back therapy was associated with
Department of Oncology, Comprehensive Cancer Centre, Helsinki University Hospital, Helsinki, Finland
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Department of Oncology, Comprehensive Cancer Centre, Helsinki University Hospital, Helsinki, Finland
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Department of Radiology, HUS Medical Imaging Centre, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Department of Radiology, HUS Medical Imaging Centre, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Endocrinology, Abdominal Centre, University of Helsinki and HUS, Helsinki, Finland
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Department of Oncology, Comprehensive Cancer Centre, Helsinki University Hospital, Helsinki, Finland
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and categorizing all abnormal hormonal laboratory results as endocrine AEs ( 22 , 23 , 24 , 25 ). In two prospective trials with 177 ( 22 ) and 339 ( 23 ) metastatic melanoma patients, respectively, the incidence and kinetics of endocrinopathy by
Clinic for Nuclear Medicine, University Hospital of Zürich, Zürich, Switzerland
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Faculty of Biomedical Sciences, Institute of Oncology Research, Università della Svizzera Italiana, Bellinzona, Switzerland
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International prospective register of systematic reviews database under the protocol number CRD42021257947. Eligibility criteria All original peer-reviewed research publications were considered. Inclusion criteria for eligible studies were: (i) at least
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3181ec124e ) 12 Greene FL & Sobin LH . The staging of cancer: a retrospective and prospective appraisal . CA 2008 58 180 – 190 . ( https://doi.org/10.3322/CA.2008.0001 ) 13 Xu Z Wang L Dai S Chen M Li F Sun J & Luo F
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of Medicine 2017 376 125 – 135 . ( https://doi.org/10.1056/nejmoa1607427 ) 12 Rinke A Müller HH Schade-Brittinger C Klose KJ Barth P Wied M Mayer C Aminossadati B Pape UF Bläker M Placebo-controlled, double-blind, prospective
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Centre de Recherche en Cancérologie de Lyon, UMR Inserm 1052 CNRS 5286, Lyon Cedex 08, France
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University of Lyon, Université Lyon 1, France
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University of Lyon, Université Lyon 1, France
Hospices Civils de Lyon, Institut de Pathologie Est, Bron Cedex, France
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Hospices Civils de Lyon, Hôpital Edouard Herriot, Gastroentérologie, Lyon Cedex 03, France
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University of Lyon, Université Lyon 1, France
Hospices Civils de Lyon, Hôpital Edouard Herriot, Chirurgie Digestive, Lyon Cedex 03, France
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Hospices Civils de Lyon, Hôpital Louis Pradel, Endocrinologie, Bron Cedex, France
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Centre de Recherche en Cancérologie de Lyon, UMR Inserm 1052 CNRS 5286, Lyon Cedex 08, France
University of Lyon, Université Lyon 1, France
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referred at all during the study period, they were included in the ‘just presented at the MDT of CoE’ group. From August 1, 2018, all patients with a NEN presented to the MDT-CoE were prospectively recorded in the NEN-Lyon-database, using a standardized
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between research factors and conclusions is exploratory. Notably, this study is the first to assess the LPFS of bone metastasis after RAIT. Moreover, considering the low incidence of DTC bone metastasis, it is difficult to conduct a prospective study, and
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for prediction of neurological outcome and death in cardiac arrest patients: results from a prospective trial . Resuscitation 2019 142 50 – 60 . ( https://doi.org/10.1016/j.resuscitation.2019.07.003 ) 2 Wihersaari L Tiainen M Skrifvars MB
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between HT and these two diseases. Further multi-centre, large-sample, prospective research studies are needed to explore the relationship between HT and these thyroid tumours. Both PTL and DSVPTC are lymphocyte-rich thyroid lesions, and sometimes it is