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characteristics (i.e. sex, age, adrenal hormone pattern, initial European Network for the Study of Adrenal Tumors (ENSAT) tumour stage, resection status of primary tumour, Ki67 proliferation index), as well as follow-up information, survival data and details about
Department of Endocrinology, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
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59 1031 – 1036 . ( https://doi.org/10.1210/JCEM-59-6-1031 ) 21 Pignatelli D Ferreira J Vendeira P Magalhães MC Vinson GP . Proliferation of capsular stem cells induced by ACTH in the rat adrenal cortex . Endocrine Research 2002 28 683
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. Interestingly, in vitro studies have shown that cortisol administration to hippocampal progenitor cells results in favouring astrocyte- over neuronal cell proliferation during the proliferation stage. However, the progenitors seem to be less affected during
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were associated with the function and development of neuronal cells. An RNA-seq study showed that the proliferation of cells is the leading functional network in hypothalamic neural-progenitor/stem cells treated with Dex ( 49 ), thereby indicating the
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aldosterone production compared to non-mutant mice ( 8 ). While in mice with constitutive activation of β-catenin, Berthon et al. ( 9 ) found adrenal hyperplasia, hyperaldosteronism, increased proliferation of glandular cells, disturbed differentiation of
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( 15 ). Despite its major role in T cell function, PTPN22 seems also implicated in B cell biology, comprising signal transduction, proliferation, and resistance to apoptosis ( 38 ). Hitherto analyses of the association between PTPN22 polymorphism