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treatment with RNase R, six RNAs from three PC and three PA tissue samples were prepared for a high-throughput circular RNA sequencing with Illumina sequencing technology from Novegene Inc. Briefly, mRNA was purified from the total RNA using poly-T oligo
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tissue, we analyzed Dkk1 mRNA levels in subcutaneous and gonadal fat and determined Dkk1 protein levels in the serum. Dkk1 fl/fl ;AdipoQcre-positive mice showed lower levels of Dkk1 in subcutaneous fat (−57%, Fig. 1D ) and in the serum (−27%, Fig. 1E
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Center for Healthy Aging, Universitätsklinikum Dresden, Technische Universität Dresden, Dresden, Germany
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(or indeed associated with various diseases). Classical chemicals-based pharmaceuticals, recombinant proteins, monoclonal antibodies and biologicals, and (very recently) mRNA-based vaccines, have successfully expanded the therapeutic spectrum, whilst
Fondazione Italiana Ricerca sulle Malattie dell’Osso (FIRMO Onlus), Florence, Italy
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perinatal BPA exposure. Authors suggest that this effect is in part due to its positive effect on the downregulation of RORγt mRNA expression, interleukin (IL)-6 and IL-23, mediated via vitamin D receptor activation ( 33 ). Age in the present study was
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://doi.org/10.1021/bi00366a051 ) 79 Cooke NE McLeod JF Wang XK Ray K . Vitamin D binding protein: genomic structure, functional domains, and mRNA expression in tissues . Journal of Steroid Biochemistry and Molecular Biology 1991 40 787 – 793