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Link between insulin resistance and skeletal muscle extracellular matrix remodeling

Róża Aleksandrowicz

Róża Aleksandrowicz Department of Prophylaxis of Metabolic Diseases, Bialystok, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland

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and

Marek Strączkowski

Marek Strączkowski Department of Prophylaxis of Metabolic Diseases, Bialystok, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland

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also of great importance ( 2 ). Insulin interacts with receptors in the cell membrane. It thus stimulates signal transduction pathway. Insulin signaling molecules include insulin receptor substrate 1 (IRS1), phosphatidylinositol 3-kinase (PI3K), and