Zherui Fu
Zherui Fu
Department of Emergency, The First People’s Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China
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Yi Lai
Yi Lai
Department of Emergency, The First People’s Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China
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Qianfei Wang
Qianfei Wang
Department of Emergency, The First People’s Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China
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Feng Lin
Feng Lin
Department of Orthopedics, The First People's Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China
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Jiaping Fang
Jiaping Fang
Department of Emergency, The First People’s Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China
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also analyzed. In addition, the correlation between LRG1 expression and immune infiltration was determined as a possible mechanism for LRG1 involvement in the progression of thyroid cancer. Our results may provide an important target for the
Camila Aparecida Moma
Camila Aparecida Moma
Endocrinology Division, Department of Internal Medicine, Faculty of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil
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Icléia Siqueira Barreto
Icléia Siqueira Barreto
Department of Pathology, Faculty of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil
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Ligia Vera Montali Assumpção
Ligia Vera Montali Assumpção
Endocrinology Division, Department of Internal Medicine, Faculty of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil
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Denise Engelbrecht Zantut-Wittmann
Denise Engelbrecht Zantut-Wittmann
Endocrinology Division, Department of Internal Medicine, Faculty of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil
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tumor microenvironment, which allows us to understand how the immune system orchestrates itself to contain neoplastic progression ( 10 , 11 , 12 , 13 , 14 ). Initially, neoplastic cells are identified and destroyed by the immune system; however
Weiwei Liang
Weiwei Liang
Department of Endocrinology and Diabetes Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
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Yilin Zhang
Yilin Zhang
Department of Endocrinology and Diabetes Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
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Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
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Yan Guo
Yan Guo
Department of Endocrinology and Diabetes Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
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Pengyuan Zhang
Pengyuan Zhang
Department of Endocrinology and Diabetes Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
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Jiewen Jin
Jiewen Jin
Department of Endocrinology and Diabetes Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
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Hongyu Guan
Hongyu Guan
Department of Endocrinology and Diabetes Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
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Yanbing Li
Yanbing Li
Department of Endocrinology and Diabetes Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
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temperature, the protein bands were visualized using enzyme-linked chemiluminescence detection (ECL) Kit (Beyotime Biotechnology, Beijing, China). Correlation analysis of FLNA and tumor immune microenvironment The correlation between FLNA and tumor
Xiaoya Zheng
Xiaoya Zheng
Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Heng Xiao
Heng Xiao
Department of Hepatobiliary Surgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Jian Long
Jian Long
Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Qiang Wei
Qiang Wei
Prevention of Disease Department, Chongqing Jiulongpo District Hospital of Traditional Chinese Medicine, Chongqing, China
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Liping Liu
Liping Liu
Department of Ultrasound, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Liping Zan
Liping Zan
Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Wei Ren
Wei Ren
Department of Endocrinology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Introduction Programmed cell death protein-1 (PD-1) blockade therapies are widely used for the treatment of hepatocellular carcinoma (HCC) ( 1 ). In addition to their antitumor effects, anti-PD-1 antibodies have been reported to cause immune
Zhengrong Jiang
Zhengrong Jiang
Department of Endocrinology, The Second affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China
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Linghong Huang
Linghong Huang
Department of Endocrinology, The Second affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China
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Lijun Chen
Lijun Chen
Department of Endocrinology, The Second affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China
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Jingxiong Zhou
Jingxiong Zhou
Department of Endocrinology, The Second affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China
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Bo Liang
Bo Liang
Department of Endocrinology, The Second affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China
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Xuefeng Bai
Xuefeng Bai
Department of Endocrinology, The Second affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China
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Lizhen Wu
Lizhen Wu
Department of Endocrinology, The Second affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China
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Huibin Huang
Huibin Huang
Department of Endocrinology, The Second affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China
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insight into the relationship between circRNAs and GD is still required. Cytokines are a group of small molecules secreted by a variety of tissue cells (mainly immune cells), which play a central role in initiating immune cascades through their receptors
Xiao-Shan Huang
Xiao-Shan Huang
Department of Radiology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China
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Ning Dai
Ning Dai
Zhejiang Chinese Medical University, Hangzhou, China
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Jian-Xia Xu
Jian-Xia Xu
Department of Radiology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China
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Jun-Yi Xiang
Jun-Yi Xiang
Department of Radiology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China
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Xiao-Zhong Zheng
Xiao-Zhong Zheng
Department of Radiology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China
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Tian-Yu Ke
Tian-Yu Ke
Department of Radiology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China
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Lin-Ying Ma
Lin-Ying Ma
Department of Radiology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China
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Qi-Hao Shi
Qi-Hao Shi
Zhejiang Chinese Medical University, Hangzhou, China
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Shu-Feng Fan
Shu-Feng Fan
Department of Radiology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China
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). Excess adipose tissue produces various cytokines and inflammatory markers, such as IL-1, IL-6, TNF-α, and leptin. These substances mediate immune and inflammatory responses ( 25 ), with leptin considered to mediate immune responses by shifting helper T
Fei Wu
Fei Wu
Department of Nuclear Medicine, Yancheng City No. 1 People’s Hospital, Yancheng, China
Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
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Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
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Chaoming Mao
Chaoming Mao
Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
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Xiao Mou
Xiao Mou
Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
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Chengcheng Xu
Chengcheng Xu
Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
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Tingting Zheng
Tingting Zheng
Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
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Ling Bu
Ling Bu
Department of Clinical Medicine, Jiangsu Health Vocational College, Nanjing, China
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Xuan Luo
Xuan Luo
Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
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Qingyan Lu
Qingyan Lu
Department of Laboratory Medicine, Xuzhou Central Hospital, Xuzhou, China
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Xuefeng Wang
Xuefeng Wang
Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
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Introduction Hashimoto’s thyroiditis (HT) is a very common organ-specific autoimmune disease in which the Th1-mediated immune response contributes to the destruction of thyroid follicular cells (TFCs) ( 1 ). In recent years, many studies have
Caiyan Mo
Caiyan Mo
Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Tao Tong
Tao Tong
Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Ying Guo
Ying Guo
Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Zheng Li
Zheng Li
Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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Liyong Zhong
Liyong Zhong
Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
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in patients with GHPA can contribute to the improvement of hyperthyroidism in GD. Several studies have confirmed the important role of GH in the pathogenesis of GD, which is involved in the immune regulation of cells by binding to receptors on the
Qian Yang
Qian Yang
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Wencai Ke
Wencai Ke
Department of Clinical Laboratory Medicine, Fifth People's Hospital of Shanghai Fudan University, Shanghai, China
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Fanfan Pan
Fanfan Pan
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Xinmei Huang
Xinmei Huang
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Jun Liu
Jun Liu
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Bingbing Zha
Bingbing Zha
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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the aim of the study. The mechanism of GD in patients with neutropenia is not completely clear. The current data cannot determine the relationship between the RAIU and the functional status of immune cells. Granulocyte colony-stimulating factor (G
Danzhou Fang
Danzhou Fang
Department of Nuclear Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Shiying Li
Shiying Li
Department of Infectious Diseases, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Changgu Zhou
Changgu Zhou
Department of Infectious Diseases, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Yirui Wang
Yirui Wang
Department of Nuclear Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Gengbiao Yuan
Gengbiao Yuan
Department of Nuclear Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
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HuiHui Zhang
HuiHui Zhang
Department of Nuclear Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Maohua Rao
Maohua Rao
Department of Nuclear Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
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( 15 ). For autoimmune hepatitis, the primary therapeutic approach is immunosuppressive therapy with glucocorticoids to quell the immune response causing liver inflammation. Monitoring of liver function, viral load, and disease progression is key to
