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Osteoporosis and vascular calcifications

Nancy Martini

Nancy Martini Laboratorio de Investigaciones en Osteopatías y Metabolismo Mineral (LIOMM-UNLP-CICPBA), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina

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Lucas Streckwall

Lucas Streckwall Laboratorio de Investigaciones en Osteopatías y Metabolismo Mineral (LIOMM-UNLP-CICPBA), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina

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, and

Antonio Desmond McCarthy

Antonio Desmond McCarthy Laboratorio de Investigaciones en Osteopatías y Metabolismo Mineral (LIOMM-UNLP-CICPBA), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina

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RANK–RANKL interaction ( 9 ). Chronic activation of the RAGE receptor (due to AGEs accumulated on the extracellular matrix under conditions of reduced renal clearance, oxidative stress, carbonyl stress and/or hyperglycaemia) stimulates osteogenic

Article Type:: Review Article

Collections:: Bone and Mineral Metabolism

DOI:: https://doi.org/10.1530/EC-23-0305

Volume/Issue:: Volume 12: Issue 11

Open access

Vitamin D deficiency in British South Asians, a persistent but avoidable problem associated with many health risks (including rickets, T2DM, CVD, COVID-19 and pregnancy complications): the case for correcting this deficiency

Barbara J Boucher

Barbara J Boucher The Blizard Institute, Queen Mary University of London, London, UK

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at least 80 nmol/L to normalise their insulin resistance ( 37 ). Also, in prediabetes with early hyperglycaemia, it took achieved 25(OH)D values of 100 nmol/L in the D2d trial for insulin resistance to be reduced ( 38 ), though 25(OH)D values of 25