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Applying precision medicine to the diagnosis and management of endocrine disorders

Martin Bidlingmaier

Martin Bidlingmaier Medizinische Klinik und Poliklinik IV, LMU Klinikum, Ludwig-Maximilians University, Munich, Germany

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Helena Gleeson

Helena Gleeson Department of Endocrinology, Queen Elizabeth Hospital, Birmingham, UK

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Ana-Claudia Latronico

Ana-Claudia Latronico Department of Internal Medicine, Discipline of Endocrinology and Metabolism, Sao Paulo Medical School, University of Sao Paulo, Sao Paulo, Brazil

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, and

Martin O Savage

Martin O Savage Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, London, UK

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on bone health. Högler et al . ( 46 ) reviewed the evidence relating to the impact of GH deficiency on bone and, in particular, reviewed all the available fracture studies. The fracture prevalence and incidence studies demonstrated evidence of

Article Type:: Review Article

Collections:: Paediatric Endocrinology

DOI:: https://doi.org/10.1530/EC-22-0177

Volume/Issue:: Volume 11: Issue 10

Open access

Functional hypogonadism in adolescence: an overlooked cause of secondary hypogonadism

Rebeca Esquivel-Zuniga

Rebeca Esquivel-Zuniga Department of Pediatrics, University of Virginia, Charlottesville, Virginia, USA

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and

Alan D Rogol

Alan D Rogol Department of Pediatrics, University of Virginia, Charlottesville, Virginia, USA

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disorder continues with time, it may become more difficult to re-gain cyclic ovarian function with bone loss or failure to accrue more (peak) bone mass being a major long-term consequence along with low bone mineral density and stress fractures, despite the