Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
Department of Family Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
Search for other papers by Hsiao-Yun Yeh in
Google Scholar
PubMed
Division of Musculoskeletal Section, Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan
Search for other papers by Hung-Ta Hondar Wu in
Google Scholar
PubMed
Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
Search for other papers by Hsiao-Chin Shen in
Google Scholar
PubMed
School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei, Taiwan
Search for other papers by Tzu-Hao Li in
Google Scholar
PubMed
Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
Search for other papers by Ying-Ying Yang in
Google Scholar
PubMed
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
Search for other papers by Kuei-Chuan Lee in
Google Scholar
PubMed
Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
Department of Family Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
Search for other papers by Yi-Hsuan Lin in
Google Scholar
PubMed
Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
Search for other papers by Chia-Chang Huang in
Google Scholar
PubMed
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
Search for other papers by Ming-Chih Hou in
Google Scholar
PubMed
fractures with a more severe clinical impact in the elderly. Having a higher BMI might be a strategy to prevent osteoporosis, as studies have observed a correlation between higher BMI and a decrease in osteoporosis-related fractures in both women and men
Search for other papers by Martine Cohen-Solal in
Google Scholar
PubMed
Search for other papers by Thomas Funck-Brentano in
Google Scholar
PubMed
Department of Renal Physiology, Necker Hospital, Université de Paris, Paris, France
Search for other papers by Pablo Ureña Torres in
Google Scholar
PubMed
to clinical events related to calcium and phosphate metabolism such as fractures, biochemical abnormalities and cardiovascular events like vascular calcifications ( 1 ). The mineral disorders were added to the previous so-called renal osteodystrophy
Search for other papers by Lu Liu in
Google Scholar
PubMed
Search for other papers by Chunyan Li in
Google Scholar
PubMed
Search for other papers by Peng Yang in
Google Scholar
PubMed
Search for other papers by Jian Zhu in
Google Scholar
PubMed
Search for other papers by Dongmei Gan in
Google Scholar
PubMed
Search for other papers by Le Bu in
Google Scholar
PubMed
Search for other papers by Manna Zhang in
Google Scholar
PubMed
Search for other papers by Chunjun Sheng in
Google Scholar
PubMed
Search for other papers by Hong Li in
Google Scholar
PubMed
Search for other papers by Shen Qu in
Google Scholar
PubMed
increasingly high risk of osteoporosis (1) . Though osteoporosis is often thought of as an older person's disease, it can strike at any age. The disease causes a significant amount of morbidity and mortality in patients and is often diagnosed after a fracture
Department of Endocrinology, University of Manchester, School of Medical Sciences, Manchester, UK
Search for other papers by Victoria Chatzimavridou-Grigoriadou in
Google Scholar
PubMed
Department of Endocrinology, University of Manchester, School of Medical Sciences, Manchester, UK
Search for other papers by Lisa H Barraclough in
Google Scholar
PubMed
Search for other papers by Rohit Kochhar in
Google Scholar
PubMed
Search for other papers by Lucy Buckley in
Google Scholar
PubMed
Search for other papers by Nooreen Alam in
Google Scholar
PubMed
Search for other papers by Claire E Higham in
Google Scholar
PubMed
importance of cancer treatment late effects and survivorship is being increasingly recognised. Bone toxicity, and more specifically radiotherapy-related insufficiency fractures (RRIFs), are well-established late effects of pelvic radiotherapy, with
Search for other papers by Alessandro Brancatella in
Google Scholar
PubMed
Search for other papers by Claudio Marcocci in
Google Scholar
PubMed
fragility fractures. Bone mineral density (BMD) Bone mineral density (BMD) estimated by dual X-ray absorptiometry (DXA) is commonly used to evaluate bone health and fracture risk. Given the good reliability and reproducibility, and low costs, BMD
Search for other papers by Giuseppe Grande in
Google Scholar
PubMed
Search for other papers by Andrea Graziani in
Google Scholar
PubMed
Search for other papers by Antonella Di Mambro in
Google Scholar
PubMed
Search for other papers by Riccardo Selice in
Google Scholar
PubMed
Department of Medicine, University of Padova, Padova, Italy
Search for other papers by Alberto Ferlin in
Google Scholar
PubMed
increased risk of fracture, due to alterations in bone density and bone quality ( 19 ). Osteoporosis in subjects with KS: definition and prevalence Dual-energy x-ray absorptiometry (DXA) is the standard technique to measure bone mineral density (BMD
Search for other papers by Enrique Soto-Pedre in
Google Scholar
PubMed
Department of Endocrinology and Diabetes, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK
Search for other papers by Paul J Newey in
Google Scholar
PubMed
Search for other papers by John S Bevan in
Google Scholar
PubMed
Department of Endocrinology and Diabetes, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK
Search for other papers by Graham P Leese in
Google Scholar
PubMed
interest. Description Admissions (SMR) ICD-9 codes ICD-10 codes Bone fractures 800–829, E887 M484, M80, M81, S02, S12, S22, S32, S42, S52, S62, S72, S82, S92, bib2, bib8, T10, T12, T142 Osteoporotic bone fractures
Search for other papers by Herjan J T Coelingh Bennink in
Google Scholar
PubMed
Search for other papers by Jan Krijgh in
Google Scholar
PubMed
Search for other papers by Jan F M Egberts in
Google Scholar
PubMed
Search for other papers by Maria Slootweg in
Google Scholar
PubMed
Search for other papers by Harm H E van Melick in
Google Scholar
PubMed
Search for other papers by Erik P M Roos in
Google Scholar
PubMed
Search for other papers by Diederik M Somford in
Google Scholar
PubMed
Search for other papers by Yvette Zimmerman in
Google Scholar
PubMed
Search for other papers by Iman J Schultz in
Google Scholar
PubMed
Search for other papers by Noel W Clarke in
Google Scholar
PubMed
Search for other papers by R Jeroen A van Moorselaar in
Google Scholar
PubMed
Search for other papers by Frans M J Debruyne in
Google Scholar
PubMed
(E) Loss of bone, decreased bone mineral density and increased fracture risk (E) Fatigue ( T and E) Erection problems (T) Gynecomastia (T and E) Metabolic syndrome (E) Sleeping problems (T and E) Hot flushes and sweating (E
Search for other papers by E M Winter in
Google Scholar
PubMed
Search for other papers by A Ireland in
Google Scholar
PubMed
Search for other papers by N C Butterfield in
Google Scholar
PubMed
Search for other papers by M Haffner-Luntzer in
Google Scholar
PubMed
Search for other papers by M-N Horcajada in
Google Scholar
PubMed
Jan van Goyen Medical Center, Department of Internal Medicine, Amsterdam, the Netherlands
Search for other papers by A G Veldhuis-Vlug in
Google Scholar
PubMed
Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
Search for other papers by L Oei in
Google Scholar
PubMed
Search for other papers by G Colaianni in
Google Scholar
PubMed
Search for other papers by N Bonnet in
Google Scholar
PubMed
pregnancy and lactation, how fracture healing is affected in these situations, and the pathophysiology of pregnancy- and lactation-induced osteoporosis (PLO). Physiological adaptation of bone to pregnancy and lactation Hormonal changes during
Search for other papers by Ann-Kristin Picke in
Google Scholar
PubMed
Search for other papers by Graeme Campbell in
Google Scholar
PubMed
Division of Bone and Mineral Diseases, Washington University in St Louis, St Louis, Missouri, USA
Search for other papers by Nicola Napoli in
Google Scholar
PubMed
Search for other papers by Lorenz C Hofbauer in
Google Scholar
PubMed
Search for other papers by Martina Rauner in
Google Scholar
PubMed
complications, the increased risk for fragility fractures has recently been recognized as an important complication of both type 1 and type 2 diabetes mellitus (T1DM, T2DM) ( 3 , 4 , 5 ). While type 1 diabetics have low bone mineral density and a six- to