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Reduced pituitary size in subjects with mutations in the THRB gene and thyroid hormone resistance

Marcus Heldmann

Marcus Heldmann Department of Neurology, University of Lübeck, Lübeck, Germany
Department of Psychology II, University of Lübeck, Lübeck, Germany

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Krishna Chatterjee

Krishna Chatterjee Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK

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Carla Moran

Carla Moran Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK

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Berenike Rogge

Berenike Rogge Department of Neurology, University of Lübeck, Lübeck, Germany

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Julia Steinhardt

Julia Steinhardt Department of Neurology, University of Lübeck, Lübeck, Germany

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Tobias Wagner-Altendorf

Tobias Wagner-Altendorf Department of Neurology, University of Lübeck, Lübeck, Germany

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Martin Göttlich

Martin Göttlich Department of Neurology, University of Lübeck, Lübeck, Germany

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Hannes Schacht

Hannes Schacht Department of Neuroradiology, University of Lübeck, Lübeck, Germany

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Peter Schramm

Peter Schramm Department of Neuroradiology, University of Lübeck, Lübeck, Germany

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Georg Brabant

Georg Brabant Department of Internal Medicine I, University of Lübeck, Lübeck, Germany
Department of Endocrinology, The Christie, University of Manchester, Manchester, UK

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Thomas F Münte

Thomas F Münte Department of Neurology, University of Lübeck, Lübeck, Germany
Department of Psychology II, University of Lübeck, Lübeck, Germany

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Anna Cirkel

Anna Cirkel Department of Neurology, University of Lübeck, Lübeck, Germany

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-iodothyronine (fT3)) and lipid profiles (total, LDL and HDL cholesterol). All participants were examined by an endocrinologist. Out of the nineteen RTHβ, only one patient received propranolol, one patient received calcidol postoperatively for hypoparathyroidism, one