Search for other papers by M Axelstad in
Google Scholar
PubMed
Search for other papers by U Hass in
Google Scholar
PubMed
Search for other papers by M Scholze in
Google Scholar
PubMed
Search for other papers by S Christiansen in
Google Scholar
PubMed
Search for other papers by A Kortenkamp in
Google Scholar
PubMed
Search for other papers by J Boberg in
Google Scholar
PubMed
-androgenic EDCs, another mixture of 4 estrogenic EDCs and a total mixture of all 12 EDCs and paracetamol were investigated. The mixture composition for the environmental EDCs was based on high-end human intakes, as described in detail by Christiansen and coworkers
Search for other papers by Xiaomin Li in
Google Scholar
PubMed
Search for other papers by Ling Fang in
Google Scholar
PubMed
Search for other papers by Hongjiang Li in
Google Scholar
PubMed
Search for other papers by Xiaoqin Yang in
Google Scholar
PubMed
, has gradually increased recently ( 1 , 2 ). In patients with breast cancer, abnormalities occur in estrogen metabolism, in particular in the level of estrogen and their metabolites. Hydroxylation of the carbon atoms at positions 2, 4, and 16 of the
Search for other papers by Herjan J T Coelingh Bennink in
Google Scholar
PubMed
Search for other papers by Jan Krijgh in
Google Scholar
PubMed
Search for other papers by Jan F M Egberts in
Google Scholar
PubMed
Search for other papers by Maria Slootweg in
Google Scholar
PubMed
Search for other papers by Harm H E van Melick in
Google Scholar
PubMed
Search for other papers by Erik P M Roos in
Google Scholar
PubMed
Search for other papers by Diederik M Somford in
Google Scholar
PubMed
Search for other papers by Yvette Zimmerman in
Google Scholar
PubMed
Search for other papers by Iman J Schultz in
Google Scholar
PubMed
Search for other papers by Noel W Clarke in
Google Scholar
PubMed
Search for other papers by R Jeroen A van Moorselaar in
Google Scholar
PubMed
Search for other papers by Frans M J Debruyne in
Google Scholar
PubMed
important estrogen in men, ADT causes serious estrogen deficiency, which is heavily underestimated and results in subjective symptoms such as hot flushes and sweats, arthralgia, fatigue, mood changes and depression, sleep disturbances, cognition problems and
Faculté de Chirurgie Dentaire, Université de Toulouse III, Toulouse, France
Search for other papers by Emmanuelle Noirrit in
Google Scholar
PubMed
Search for other papers by Mélissa Buscato in
Google Scholar
PubMed
Search for other papers by Marion Dupuis in
Google Scholar
PubMed
CHU de Toulouse, Laboratoire d’Hématologie, Toulouse, France
Search for other papers by Bernard Payrastre in
Google Scholar
PubMed
Search for other papers by Coralie Fontaine in
Google Scholar
PubMed
Search for other papers by Jean-François Arnal in
Google Scholar
PubMed
Faculté de Chirurgie Dentaire, Université de Toulouse III, Toulouse, France
Search for other papers by Marie-Cécile Valera in
Google Scholar
PubMed
Introduction Menopause is defined as the permanent cessation of menstruation and ovulation due to ovarian failure. The decline in estrogen and progesterone levels in women can lead to a number of bothersome symptoms. The most common include
Search for other papers by Yali Cheng in
Google Scholar
PubMed
Search for other papers by Qiaoying Lv in
Google Scholar
PubMed
Search for other papers by Bingying Xie in
Google Scholar
PubMed
Search for other papers by Bingyi Yang in
Google Scholar
PubMed
Search for other papers by Weiwei Shan in
Google Scholar
PubMed
Search for other papers by Chengcheng Ning in
Google Scholar
PubMed
Search for other papers by Bing Li in
Google Scholar
PubMed
Search for other papers by Liying Xie in
Google Scholar
PubMed
Search for other papers by Chao Gu in
Google Scholar
PubMed
Search for other papers by Xuezhen Luo in
Google Scholar
PubMed
Search for other papers by Xiaojun Chen in
Google Scholar
PubMed
Search for other papers by Qin Zhu in
Google Scholar
PubMed
Introduction Endometrial cancer (EC) is one of the most common malignant genital tumors among females worldwide, with an estimated 61,380 new cases in America in 2017 ( 1 ). It is known that type1 EC is estrogen-dependent tumor. Sustained
Search for other papers by Anastasia K Armeni in
Google Scholar
PubMed
Search for other papers by Konstantinos Assimakopoulos in
Google Scholar
PubMed
Search for other papers by Dimitra Marioli in
Google Scholar
PubMed
Search for other papers by Vassiliki Koika in
Google Scholar
PubMed
Search for other papers by Euthychia Michaelidou in
Google Scholar
PubMed
Search for other papers by Niki Mourtzi in
Google Scholar
PubMed
Search for other papers by Gregoris Iconomou in
Google Scholar
PubMed
Search for other papers by Neoklis A Georgopoulos in
Google Scholar
PubMed
moderate size. Data have shown that additive and non-additive genetic effects explained 21–35% of the variation in desire, 24–26% in subjective arousal and 16–25% in lubrication ( 1 , 2 ). Central regulatory role of estrogens in female sexuality is
Department of Molecular Endocrinology, National Research Institute for Child Health and Development, Setagaya, Tokyo, Japan
Search for other papers by Maki Igarashi in
Google Scholar
PubMed
Department of Molecular Endocrinology, National Research Institute for Child Health and Development, Setagaya, Tokyo, Japan
Search for other papers by Tadayuki Ayabe in
Google Scholar
PubMed
Search for other papers by Kiwako Yamamoto-Hanada in
Google Scholar
PubMed
Search for other papers by Keiko Matsubara in
Google Scholar
PubMed
Search for other papers by Hatoko Sasaki in
Google Scholar
PubMed
Search for other papers by Mayako Saito-Abe in
Google Scholar
PubMed
Search for other papers by Miori Sato in
Google Scholar
PubMed
Search for other papers by Nathan Mise in
Google Scholar
PubMed
Search for other papers by Akihiko Ikegami in
Google Scholar
PubMed
Search for other papers by Masayuki Shimono in
Google Scholar
PubMed
Search for other papers by Reiko Suga in
Google Scholar
PubMed
Research Center for Environment and Developmental Medical Sciences, Kyushu University, Higashi-ku, Fukuoka, Japan
Search for other papers by Shouichi Ohga in
Google Scholar
PubMed
Research Center for Environment and Developmental Medical Sciences, Kyushu University, Higashi-ku, Fukuoka, Japan
Search for other papers by Masafumi Sanefuji in
Google Scholar
PubMed
Search for other papers by Masako Oda in
Google Scholar
PubMed
Search for other papers by Hiroshi Mitsubuchi in
Google Scholar
PubMed
Search for other papers by Takehiro Michikawa in
Google Scholar
PubMed
Search for other papers by Shin Yamazaki in
Google Scholar
PubMed
Search for other papers by Shoji Nakayama in
Google Scholar
PubMed
Search for other papers by Yukihiro Ohya in
Google Scholar
PubMed
Department of Molecular Endocrinology, National Research Institute for Child Health and Development, Setagaya, Tokyo, Japan
Search for other papers by Maki Fukami in
Google Scholar
PubMed
Landersoe SK Petersen JH Andersen AN Vestergaard ET Schorring ME Linneberg A Sex-specific estrogen levels and reference intervals from infancy to late adulthood determined by LC-MS/MS . Journal of Clinical Endocrinology and Metabolism 2020 105
Search for other papers by Lauren R Cirrincione in
Google Scholar
PubMed
Search for other papers by Bridgit O Crews in
Google Scholar
PubMed
Search for other papers by Jane A Dickerson in
Google Scholar
PubMed
Search for other papers by Matthew D Krasowski in
Google Scholar
PubMed
Search for other papers by Jessica Rongitsch in
Google Scholar
PubMed
Search for other papers by Katherine L Imborek in
Google Scholar
PubMed
CUNY Graduate School of Public Health and Health Policy, New York, New York, USA
Search for other papers by Zil Goldstein in
Google Scholar
PubMed
Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA
Search for other papers by Dina N Greene in
Google Scholar
PubMed
time, and affordability ( 5 ). Despite these advantages, early reports established cross-reactivity between estrogenic metabolites (including unconjugated and conjugated estrone, a weak estrogen) and anti-estradiol antibodies used in immunoassays ( 4
Faculty of Medicine, University of Freiburg, Freiburg, Germany
Search for other papers by Jasmin Asberger in
Google Scholar
PubMed
Faculty of Medicine, University of Freiburg, Freiburg, Germany
Search for other papers by Thalia Erbes in
Google Scholar
PubMed
Faculty of Medicine, University of Freiburg, Freiburg, Germany
Search for other papers by Markus Jaeger in
Google Scholar
PubMed
Search for other papers by Gerta Rücker in
Google Scholar
PubMed
Faculty of Medicine, University of Freiburg, Freiburg, Germany
Search for other papers by Claudia Nöthling in
Google Scholar
PubMed
Faculty of Medicine, University of Freiburg, Freiburg, Germany
Search for other papers by Andrea Ritter in
Google Scholar
PubMed
Faculty of Medicine, University of Freiburg, Freiburg, Germany
Search for other papers by Kai Berner in
Google Scholar
PubMed
Faculty of Medicine, University of Freiburg, Freiburg, Germany
Search for other papers by Ingolf Juhasz-Böss in
Google Scholar
PubMed
Faculty of Medicine, University of Freiburg, Freiburg, Germany
Institute of Veterinary Medicine, Georg-August-University Goettingen, Goettingen, Germany
Search for other papers by Marc Hirschfeld in
Google Scholar
PubMed
can be categorized according to different endocrine effects: selective oestrogen-receptor modulators (SERMs), aromatase inhibitors (AIs), and selective estrogen-receptor downregulator (SERD) ( 7 ). The selective oestrogen receptor modulator (SERM
Search for other papers by Charissa van Zwol-Janssens in
Google Scholar
PubMed
Search for other papers by Aglaia Hage in
Google Scholar
PubMed
Search for other papers by Kim van der Ham in
Google Scholar
PubMed
Search for other papers by Birgitta K Velthuis in
Google Scholar
PubMed
Search for other papers by Ricardo P J Budde in
Google Scholar
PubMed
Search for other papers by Maria P H Koster in
Google Scholar
PubMed
Search for other papers by Arie Franx in
Google Scholar
PubMed
Search for other papers by Bart C J M Fauser in
Google Scholar
PubMed
Search for other papers by Eric Boersma in
Google Scholar
PubMed
Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands
Search for other papers by Daniel Bos in
Google Scholar
PubMed
Search for other papers by Joop S E Laven in
Google Scholar
PubMed
Search for other papers by Yvonne V Louwers in
Google Scholar
PubMed
Search for other papers by the CREW consortium in
Google Scholar
PubMed
risk for failure to attain peak bone mass or for early loss of BD, due to estrogen deficiency at an early age ( 1 , 2 , 3 , 4 , 5 ). Consequently, women with POI are advised to use hormone replacement therapy (HRT) ( 6 ). In contrast to POI, the