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. Estrogen plays its role mainly through the estrogen receptor (ER), which includes ER-α and ER-β; it plays a regulatory role by directly acting on the genome by binding to the ERE of the target gene ( 15 ). Building on these findings, we aimed to explore the
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the other hand, it has been shown that the sympathetic input activated by sexual behavior increases prostate DIO1 activity after consecutive ejaculations ( 13 ). In addition, DIO1 activity is under endocrine control; it is stimulated by T4, estrogens
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on weight was not well understood. In this study, higher FT3 and FT3/FT4 and lower FT4 increased the risk of central obesity; however, this was not found in females, which may be related to the protective effect of estrogen in females ( 26 , 27
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Xiong Q Liu F Yuan J Zhao X Wang R . Resveratrol downregulates PCSK9 expression and attenuates steatosis through estrogen receptor α-mediated pathway in L02 cells . European Journal of Pharmacology 2019 855 216 – 226 . ( https://doi.org/10