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important estrogen in men, ADT causes serious estrogen deficiency, which is heavily underestimated and results in subjective symptoms such as hot flushes and sweats, arthralgia, fatigue, mood changes and depression, sleep disturbances, cognition problems and
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Diagnostic Clinic, University Hospital of North Norway, Tromso, Norway
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hormonal contraceptives (CHC), which includes an estrogenic component, has been consistently reported ( 3 , 11 ). Several tissues, including the parathyroid gland, can utilize DBP-bound 25(OH)D, possibly modifying the significance of free 25(OH)D levels
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that estrogen is strongly related to osteoporosis, and estrogen deficiency can lead to increased apoptosis on osteoblast, bone loss, and osteoporosis ( 7 , 31 ). We speculated that it might be related to changes in sex hormone levels after menopause
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and may have limitations. The role of sUA on BMD in postmenopausal women Postmenopausal women often show a higher prevalence of OP due to factors such as estrogen deficiency, and studies have shown a positive correlation between sUA and BMD in
Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
Department of Family Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
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Division of Musculoskeletal Section, Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan
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Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
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School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei, Taiwan
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Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
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Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
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Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
Department of Family Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
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Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
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Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
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( 11 ). Postmenopausal women have a higher prevalence of osteoporosis and a higher incidence of fractures than older men ( 12 ). The decline in estrogen during menopause accelerates bone loss in women, whereas men experience a more gradual decline in
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.2174/138945011793591617 ) 46 Wang J Zhou JJ Robertson GR & Lee VW . Vitamin D in vascular calcification: a double-edged sword? Nutrients 2018 10 652 . ( https://doi.org/10.3390/nu10050652 ) 47 Chakrabarti S Lekontseva O & Davidge ST . Estrogen is a
Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
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Kiel Institute for the World Economy, Kiel, Germany
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increasing trend is observed in the risk of fragility fractures. After menopause, rapid bone loss occurs in women due to reduced estrogen levels, followed by age-related bone loss in elderly women and men. However, in the population less than 50 years
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Center for Biochemistry, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany
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Center for Biochemistry, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany
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Center for Biochemistry, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany
Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany
Cologne Center for Musculoskeletal Biomechanics (CCMB), Cologne, Germany
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Bartlova M Lacinova Z Ticha I Krejci V Springer D Kleibl Z Haluzik M . Expression of adipokines and estrogen receptors in adipose tissue and placenta of patients with gestational diabetes mellitus . Molecular and Cellular Endocrinology 2010
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Paediatric Neurosciences Research Group, Royal Hospital for Children, NHS Greater Glasgow & Clyde, Glasgow, UK
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.1210/edrv.19.1.0324 ) 33 Venken K De Gendt K Boonen S Ophoff J Bouillon R Swinnen JV Verhoeven G Vanderschueren D . Relative impact of androgen and estrogen receptor activation in the effects of androgens on trabecular and cortical bone in
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CIC INSERM 1411, Hôpital Gui de Chauliac, CHU Montpellier, Montpellier Cedex 5, France
Institut de Génomique Fonctionnelle, CNRS UMR 5203/INSERM U661/Université Montpellier, Montpellier, France
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Département de Biochimie, Hôpital Lapeyronie, CHU Montpellier, Montpellier, France
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Département Endocrinologie, Nutrition, Diabète, Equipe Nutrition, Diabète, CHU Montpellier, Montpellier, France
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. Journal of Pediatrics 2002 141 64 – 70 . ( https://doi.org/10.1067/mpd.2002.125003 ) 6 Grinspoon S Miller K Coyle C Krempin J Armstrong C Pitts S Herzog D Klibanski A . Severity of osteopenia in estrogen-deficient women with anorexia