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Department of Endocrinology, The Affiliated Hospital of Guilin Medical University, Guilin, China
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that coupled oxidative phosphorylation and uncoupled respiration may play an important role in the impairment of mitochondrial energy metabolism in skeletal muscles ( 49 , 50 ). Excess thyroid hormone levels accelerate protein catabolism and reduce
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Introduction Thyroid hormones play an important role in almost all biological processes in humans such as energy metabolism, cell growth, development, cardiovascular system, CNS, immunity and bone metabolism ( 1 , 2 ). Importantly, several
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energy metabolism by activating the AMPK-SIRT1-PGC-1alpha pathway . PNAS 2010 107 12553 – 12558 . ( https://doi.org/10.1073/pnas.1006962107 ) 74 Iizuka K Takao K Kato T Horikawa Y Takeda J . ChREBP reciprocally regulates liver and plasma