Filter

Refine by collections

  • Paediatric Endocrinology Collection (21)

Refine by date

—
  • Print
  • Save

Search Results

You are looking at 1 - 10 of 21 items for :

  • "development" x
  • Paediatric Endocrinology Collection x
Clear All
Britt J van Keulen Emma Children’s Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Pediatric Endocrinology, Amsterdam, The Netherlands

Search for other papers by Britt J van Keulen in
Google Scholar
PubMed Close
,
Conor V Dolan Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands

Search for other papers by Conor V Dolan in
Google Scholar
PubMed Close
,
Bibian van der Voorn Department of Pediatric Endocrinology, Sophia Kinderziekenhuis, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands

Search for other papers by Bibian van der Voorn in
Google Scholar
PubMed Close
,
Ruth Andrew Centre for Cardiovascular Science, University of Edinburgh, Queen’s Medical Research Institute, Edinburgh, UK

Search for other papers by Ruth Andrew in
Google Scholar
PubMed Close
,
Brian R Walker Centre for Cardiovascular Science, University of Edinburgh, Queen’s Medical Research Institute, Edinburgh, UK
Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK

Search for other papers by Brian R Walker in
Google Scholar
PubMed Close
,
Hilleke Hulshoff Pol Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands

Search for other papers by Hilleke Hulshoff Pol in
Google Scholar
PubMed Close
,
Dorret I Boomsma Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands

Search for other papers by Dorret I Boomsma in
Google Scholar
PubMed Close
,
Joost Rotteveel Emma Children’s Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Pediatric Endocrinology, Amsterdam, The Netherlands

Search for other papers by Joost Rotteveel in
Google Scholar
PubMed Close
, and
Martijn J J Finken Emma Children’s Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Pediatric Endocrinology, Amsterdam, The Netherlands

Search for other papers by Martijn J J Finken in
Google Scholar
PubMed Close

, there are no studies that have reported on HPA-axis activity across pubertal development. HPA-axis activity is determined by the net effect of cortisol production and metabolism. Cortisol is metabolized by various enzymes ( Fig. 1 ). The A

Article Type:
Research Article
Collections:
Paediatric Endocrinology Collection
DOI:
https://doi.org/10.1530/EC-20-0123
Volume/Issue:
Volume 9: Issue 6
Open access
Letícia Ribeiro Oliveira Interdisciplinary Group for Studies of Sex Determination and Differentiation (GIEDDS), School of Medical Sciences (FCM), State University of Campinas (UNICAMP), Campinas, Sao Paulo, Brazil
Department of Pediatrics, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais, Brazil

Search for other papers by Letícia Ribeiro Oliveira in
Google Scholar
PubMed Close
,
Carlos Alberto Longui Pediatric Endocrinology Unit, School of Medical Sciences, Irmandade da Santa Casa de Misericordia de Sao Paulo, Sao Paulo, Brazil

Search for other papers by Carlos Alberto Longui in
Google Scholar
PubMed Close
,
Guilherme Guaragna-Filho Interdisciplinary Group for Studies of Sex Determination and Differentiation (GIEDDS), School of Medical Sciences (FCM), State University of Campinas (UNICAMP), Campinas, Sao Paulo, Brazil
Department of Pediatrics, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil

Search for other papers by Guilherme Guaragna-Filho in
Google Scholar
PubMed Close
,
José Luiz Costa School of Pharmaceutical Sciences, UNICAMP, Campinas, Sao Paulo, Brazil
Poison Control Center, FCM, UNICAMP, Campinas, Sao Paulo, Brazil

Search for other papers by José Luiz Costa in
Google Scholar
PubMed Close
,
Rafael Lanaro Poison Control Center, FCM, UNICAMP, Campinas, Sao Paulo, Brazil

Search for other papers by Rafael Lanaro in
Google Scholar
PubMed Close
,
David Antônio Silva Laboratory of Physiology, Division of Clinical Pathology, Clinical Hospital, UNICAMP, Campinas, Sao Paulo, Brazil

Search for other papers by David Antônio Silva in
Google Scholar
PubMed Close
,
Maria Izabel Chiamolera Fleury Group, Sao Paulo, Brazil

Search for other papers by Maria Izabel Chiamolera in
Google Scholar
PubMed Close
,
Maricilda Palandi de Mello Interdisciplinary Group for Studies of Sex Determination and Differentiation (GIEDDS), School of Medical Sciences (FCM), State University of Campinas (UNICAMP), Campinas, Sao Paulo, Brazil
Laboratory of Human Molecular Genetics, Center for Molecular Biology and Genetics Engineering (CBMEG), UNICAMP, Campinas, Sao Paulo, Brazil

Search for other papers by Maricilda Palandi de Mello in
Google Scholar
PubMed Close
,
André Moreno Morcillo Department of Pediatrics, FCM, UNICAMP, Campinas, Sao Paulo, Brazil

Search for other papers by André Moreno Morcillo in
Google Scholar
PubMed Close
,
Andrea Trevas Maciel-Guerra Interdisciplinary Group for Studies of Sex Determination and Differentiation (GIEDDS), School of Medical Sciences (FCM), State University of Campinas (UNICAMP), Campinas, Sao Paulo, Brazil
Department of Medical Genetics and Genomic Medicine, FCM, UNICAMP, Campinas, Sao Paulo, Brazil

Search for other papers by Andrea Trevas Maciel-Guerra in
Google Scholar
PubMed Close
, and
Gil Guerra-Junior Interdisciplinary Group for Studies of Sex Determination and Differentiation (GIEDDS), School of Medical Sciences (FCM), State University of Campinas (UNICAMP), Campinas, Sao Paulo, Brazil
Department of Pediatrics, FCM, UNICAMP, Campinas, Sao Paulo, Brazil

Search for other papers by Gil Guerra-Junior in
Google Scholar
PubMed Close

Introduction The determination of steroid hormone concentration, which is part of the initial approach in the diagnosis of disorders of sex development (DSD), is one of the challenges in pediatric endocrinology ( 1 , 2 , 3 ). Based on the

Article Type:
Research Article
Collections:
Paediatric Endocrinology Collection
DOI:
https://doi.org/10.1530/EC-20-0454
Volume/Issue:
Volume 9: Issue 11
Open access
Britt J van Keulen Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands
Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands

Search for other papers by Britt J van Keulen in
Google Scholar
PubMed Close
,
Michelle Romijn Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands
Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands

Search for other papers by Michelle Romijn in
Google Scholar
PubMed Close
,
Bibian van der Voorn Department of Pediatric Endocrinology, Sophia Kinderziekenhuis, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands

Search for other papers by Bibian van der Voorn in
Google Scholar
PubMed Close
,
Marita de Waard Emma Children’s Hospital, Amsterdam University Medical Centers, locations AMC and VUmc, Amsterdam, The Netherlands

Search for other papers by Marita de Waard in
Google Scholar
PubMed Close
,
Michaela F Hartmann Steroid Research and Mass Spectrometry Unit, Laboratory for Translational Hormone Analytics, Pediatric Endocrinology & Diabetology, Center of Child and Adolescent Medicine, Justus-Liebig-University, Giessen, Germany

Search for other papers by Michaela F Hartmann in
Google Scholar
PubMed Close
,
Johannes B van Goudoever Emma Children’s Hospital, Amsterdam University Medical Centers, locations AMC and VUmc, Amsterdam, The Netherlands

Search for other papers by Johannes B van Goudoever in
Google Scholar
PubMed Close
,
Stefan A Wudy Steroid Research and Mass Spectrometry Unit, Laboratory for Translational Hormone Analytics, Pediatric Endocrinology & Diabetology, Center of Child and Adolescent Medicine, Justus-Liebig-University, Giessen, Germany

Search for other papers by Stefan A Wudy in
Google Scholar
PubMed Close
,
Joost Rotteveel Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands

Search for other papers by Joost Rotteveel in
Google Scholar
PubMed Close
, and
Martijn J J Finken Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands
Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands

Search for other papers by Martijn J J Finken in
Google Scholar
PubMed Close

seems warranted. Secondly, urine samples were only collected at 10 days post-partum. Preferably, urine samples would have been collected at multiple days during the first weeks of life for a more precise assessment of HPA axis development. Thirdly, we

Article Type:
Research Article
Collections:
Paediatric Endocrinology Collection
DOI:
https://doi.org/10.1530/EC-20-0587
Volume/Issue:
Volume 10: Issue 2
Open access
Maki Igarashi Medical Support Center for Japan Environmental and Children’s Study, National Center for Child Health and Development, Setagaya, Tokyo, Japan
Department of Molecular Endocrinology, National Research Institute for Child Health and Development, Setagaya, Tokyo, Japan

Search for other papers by Maki Igarashi in
Google Scholar
PubMed Close
,
Tadayuki Ayabe Medical Support Center for Japan Environmental and Children’s Study, National Center for Child Health and Development, Setagaya, Tokyo, Japan
Department of Molecular Endocrinology, National Research Institute for Child Health and Development, Setagaya, Tokyo, Japan

Search for other papers by Tadayuki Ayabe in
Google Scholar
PubMed Close
,
Kiwako Yamamoto-Hanada Medical Support Center for Japan Environmental and Children’s Study, National Center for Child Health and Development, Setagaya, Tokyo, Japan

Search for other papers by Kiwako Yamamoto-Hanada in
Google Scholar
PubMed Close
,
Keiko Matsubara Department of Molecular Endocrinology, National Research Institute for Child Health and Development, Setagaya, Tokyo, Japan

Search for other papers by Keiko Matsubara in
Google Scholar
PubMed Close
,
Hatoko Sasaki Medical Support Center for Japan Environmental and Children’s Study, National Center for Child Health and Development, Setagaya, Tokyo, Japan

Search for other papers by Hatoko Sasaki in
Google Scholar
PubMed Close
,
Mayako Saito-Abe Medical Support Center for Japan Environmental and Children’s Study, National Center for Child Health and Development, Setagaya, Tokyo, Japan

Search for other papers by Mayako Saito-Abe in
Google Scholar
PubMed Close
,
Miori Sato Medical Support Center for Japan Environmental and Children’s Study, National Center for Child Health and Development, Setagaya, Tokyo, Japan

Search for other papers by Miori Sato in
Google Scholar
PubMed Close
,
Nathan Mise Department of Environmental and Preventive Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan

Search for other papers by Nathan Mise in
Google Scholar
PubMed Close
,
Akihiko Ikegami Department of Environmental and Preventive Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan

Search for other papers by Akihiko Ikegami in
Google Scholar
PubMed Close
,
Masayuki Shimono Regional Center for Pilot Study of Japan Environment and Children’s Study, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan

Search for other papers by Masayuki Shimono in
Google Scholar
PubMed Close
,
Reiko Suga Regional Center for Pilot Study of Japan Environment and Children’s Study, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan

Search for other papers by Reiko Suga in
Google Scholar
PubMed Close
,
Shouichi Ohga Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Higashi-ku, Fukuoka, Japan
Research Center for Environment and Developmental Medical Sciences, Kyushu University, Higashi-ku, Fukuoka, Japan

Search for other papers by Shouichi Ohga in
Google Scholar
PubMed Close
,
Masafumi Sanefuji Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Higashi-ku, Fukuoka, Japan
Research Center for Environment and Developmental Medical Sciences, Kyushu University, Higashi-ku, Fukuoka, Japan

Search for other papers by Masafumi Sanefuji in
Google Scholar
PubMed Close
,
Masako Oda Department of Public Health, Faculty of Life Sciences, Kumamoto University, Chuo-ku, Kumamoto, Japan

Search for other papers by Masako Oda in
Google Scholar
PubMed Close
,
Hiroshi Mitsubuchi Department of Neonatology, Kumamoto University Hospital, Chuo-ku, Kumamoto, Japan

Search for other papers by Hiroshi Mitsubuchi in
Google Scholar
PubMed Close
,
Takehiro Michikawa Japan Environment and Children’s Study Programme Office, National Institute for Environmental Studies, Tsukuba, Ibaraki, Japan

Search for other papers by Takehiro Michikawa in
Google Scholar
PubMed Close
,
Shin Yamazaki Japan Environment and Children’s Study Programme Office, National Institute for Environmental Studies, Tsukuba, Ibaraki, Japan

Search for other papers by Shin Yamazaki in
Google Scholar
PubMed Close
,
Shoji Nakayama Japan Environment and Children’s Study Programme Office, National Institute for Environmental Studies, Tsukuba, Ibaraki, Japan

Search for other papers by Shoji Nakayama in
Google Scholar
PubMed Close
,
Yukihiro Ohya Medical Support Center for Japan Environmental and Children’s Study, National Center for Child Health and Development, Setagaya, Tokyo, Japan

Search for other papers by Yukihiro Ohya in
Google Scholar
PubMed Close
, and
Maki Fukami Medical Support Center for Japan Environmental and Children’s Study, National Center for Child Health and Development, Setagaya, Tokyo, Japan
Department of Molecular Endocrinology, National Research Institute for Child Health and Development, Setagaya, Tokyo, Japan

Search for other papers by Maki Fukami in
Google Scholar
PubMed Close

Objective

Ultra-sensitive hormone assays have detected slight sex differences in blood estradiol (E2) levels in young children before adrenarche. However, the origin of circulating E2 in these individuals remains unknown. This study aimed to clarify how E2 is produced in young girls before adrenarche.

Design

This is a satellite project of the Japan Environment and Children’s Study organized by the National Institute for Environmental Studies.

Methods

We collected blood samples from healthy 6-year-old Japanese children (79 boys and 71 girls). Hormone measurements and data analysis were performed in the National Institute for Environmental Studies and the Medical Support Center of the Japan Environment and Children’s Study, respectively.

Results

E2 and follicle stimulating hormone (FSH) levels were significantly higher in girls than in boys, while dehydroepiandrosterone sulfate (DHEA-S) and testosterone levels were comparable between the two groups. Girls showed significantly higher E2/testosterone ratios than boys. In children of both sexes, a correlation was observed between E2 and testosterone levels and between testosterone and DHEA-S levels. Moreover, E2 levels were correlated with FSH levels only in girls.

Conclusions

The results indicate that in 6-year-old girls, circulating E2 is produced primarily in the ovary from adrenal steroids through FSH-induced aromatase upregulation. This study provides evidence that female-dominant E2 production starts several months or years before adrenarche. The biological significance of E2 biosynthesis in these young children needs to be clarified in future studies.

Article Type:
Research Article
Collections:
Paediatric Endocrinology Collection
DOI:
https://doi.org/10.1530/EC-21-0134
Volume/Issue:
Volume 10: Issue 10
Open access
Valentina Guarnotta Dipartimento di Promozione della Salute, Materno-Infantile, Medicina Interna e Specialistica di Eccellenza ‘G. D’Alessandro’ (PROMISE), Sezione di Malattie Endocrine, del Ricambio e della Nutrizione, Università di Palermo, Palermo, Italy

Search for other papers by Valentina Guarnotta in
Google Scholar
PubMed Close
,
Silvia Lucchese Dipartimento di Promozione della Salute, Materno-Infantile, Medicina Interna e Specialistica di Eccellenza ‘G. D’Alessandro’ (PROMISE), Sezione di Malattie Endocrine, del Ricambio e della Nutrizione, Università di Palermo, Palermo, Italy

Search for other papers by Silvia Lucchese in
Google Scholar
PubMed Close
,
Mariagrazia Irene Mineo Dipartimento di Promozione della Salute, Materno-Infantile, Medicina Interna e Specialistica di Eccellenza ‘G. D’Alessandro’ (PROMISE), Sezione di Malattie Endocrine, del Ricambio e della Nutrizione, Università di Palermo, Palermo, Italy

Search for other papers by Mariagrazia Irene Mineo in
Google Scholar
PubMed Close
,
Donatella Mangione Dipartimento di Promozione della Salute, Materno-Infantile, Medicina Interna e Specialistica di Eccellenza ‘G. D’Alessandro’ (PROMISE), Sezione di Ostetricia e Ginecologia, Università di Palermo, Palermo, Italy

Search for other papers by Donatella Mangione in
Google Scholar
PubMed Close
,
Renato Venezia Dipartimento di Promozione della Salute, Materno-Infantile, Medicina Interna e Specialistica di Eccellenza ‘G. D’Alessandro’ (PROMISE), Sezione di Ostetricia e Ginecologia, Università di Palermo, Palermo, Italy

Search for other papers by Renato Venezia in
Google Scholar
PubMed Close
,
Piero Luigi Almasio Dipartimento di Promozione della Salute, Materno-Infantile, Medicina Interna e Specialistica di Eccellenza ‘G. D’Alessandro’ (PROMISE), Sezione di Gastroenterologia ed Epatologia, Università di Palermo, Palermo, Italy

Search for other papers by Piero Luigi Almasio in
Google Scholar
PubMed Close
, and
Carla Giordano Dipartimento di Promozione della Salute, Materno-Infantile, Medicina Interna e Specialistica di Eccellenza ‘G. D’Alessandro’ (PROMISE), Sezione di Malattie Endocrine, del Ricambio e della Nutrizione, Università di Palermo, Palermo, Italy

Search for other papers by Carla Giordano in
Google Scholar
PubMed Close

with PP that are associated with the development of PCOS and to establish predictive factors for PCOS in this population. Materials and methods This retrospective cohort study was carried out in patients with PP who developed or did not develop

Article Type:
Research Article
Collections:
Paediatric Endocrinology Collection
DOI:
https://doi.org/10.1530/EC-21-0118
Volume/Issue:
Volume 10: Issue 7
Open access
Isabelle Flechtner Center for Rare Gynecological Disorders, Centre des Pathologies Gynécologiques Rares, Paris, France
Department of Paediatric Endocrinology, Gynaecology, and Diabetology, AP-HP, Necker-Enfants Malades University Hospital, IMAGINE Institute affiliate, Paris, France

Search for other papers by Isabelle Flechtner in
Google Scholar
PubMed Close
,
Magali Viaud Center for Rare Gynecological Disorders, Centre des Pathologies Gynécologiques Rares, Paris, France
Department of Paediatric Endocrinology, Gynaecology, and Diabetology, AP-HP, Necker-Enfants Malades University Hospital, IMAGINE Institute affiliate, Paris, France

Search for other papers by Magali Viaud in
Google Scholar
PubMed Close
,
Dulanjalee Kariyawasam Department of Paediatric Endocrinology, Gynaecology, and Diabetology, AP-HP, Necker-Enfants Malades University Hospital, IMAGINE Institute affiliate, Paris, France

Search for other papers by Dulanjalee Kariyawasam in
Google Scholar
PubMed Close
,
Marie Perrissin-Fabert Center for Rare Gynecological Disorders, Centre des Pathologies Gynécologiques Rares, Paris, France
Department of Paediatric Endocrinology, Gynaecology, and Diabetology, AP-HP, Necker-Enfants Malades University Hospital, IMAGINE Institute affiliate, Paris, France

Search for other papers by Marie Perrissin-Fabert in
Google Scholar
PubMed Close
,
Maud Bidet Center for Rare Gynecological Disorders, Centre des Pathologies Gynécologiques Rares, Paris, France
Department of Paediatric Endocrinology, Gynaecology, and Diabetology, AP-HP, Necker-Enfants Malades University Hospital, IMAGINE Institute affiliate, Paris, France

Search for other papers by Maud Bidet in
Google Scholar
PubMed Close
,
Anne Bachelot Center for Rare Gynecological Disorders, Centre des Pathologies Gynécologiques Rares, Paris, France
Department of Endocrinology and Reproductive Medicine, AP-HPIE3M, Hôpital Pitié-Salpêtrière, ICAN, Paris, France

Search for other papers by Anne Bachelot in
Google Scholar
PubMed Close
,
Philippe Touraine Center for Rare Gynecological Disorders, Centre des Pathologies Gynécologiques Rares, Paris, France
Department of Endocrinology and Reproductive Medicine, AP-HPIE3M, Hôpital Pitié-Salpêtrière, ICAN, Paris, France

Search for other papers by Philippe Touraine in
Google Scholar
PubMed Close
,
Philippe Labrune Department of Pediatrics, APHP, Centre de Référence des Maladies héréditaires du Métabolisme Hépatique, Hopital Antoine Béclère and Paris Sud University, Clamart, France

Search for other papers by Philippe Labrune in
Google Scholar
PubMed Close
,
Pascale de Lonlay Reference Center of Inherited Metabolic Diseases, Université de Paris, Necker Enfants Malades, University Hospital, Paris, France
Centre for Rare Gynecological Disorders, Hospital Universitaire Necker-Enfants Malades, Paediatric Endocrinology, Gynaecology and Diabetology, AP-HP, Université de Paris, Paris, France

Search for other papers by Pascale de Lonlay in
Google Scholar
PubMed Close
, and
Michel Polak Center for Rare Gynecological Disorders, Centre des Pathologies Gynécologiques Rares, Paris, France
Department of Paediatric Endocrinology, Gynaecology, and Diabetology, AP-HP, Necker-Enfants Malades University Hospital, IMAGINE Institute affiliate, Paris, France
Centre for Rare Gynecological Disorders, Hospital Universitaire Necker-Enfants Malades, Paediatric Endocrinology, Gynaecology and Diabetology, AP-HP, Université de Paris, Paris, France

Search for other papers by Michel Polak in
Google Scholar
PubMed Close

prevent the development of long-term complications including neurological impairments (developmental delay, particularly affecting speech, low intellectual quotient and sometimes epilepsy) ( 7 ), osteoporosis and premature ovarian insufficiency (POI) ( 8

Article Type:
Research Article
Collections:
Paediatric Endocrinology Collection
DOI:
https://doi.org/10.1530/EC-21-0013
Volume/Issue:
Volume 10: Issue 2
Open access
Teodoro Durá-Travé Department of Pediatrics, School of Medicine, University of Navarra, Pamplona, Spain
Department of Pediatrics, Navarra Hospital Complex, Pamplona, Spain
Navarra Institute for Health Research (IdisNA), Pamplona, Spain

Search for other papers by Teodoro Durá-Travé in
Google Scholar
PubMed Close
,
Fidel Gallinas-Victoriano Department of Pediatrics, Navarra Hospital Complex, Pamplona, Spain

Search for other papers by Fidel Gallinas-Victoriano in
Google Scholar
PubMed Close
,
María Malumbres-Chacon Department of Pediatrics, Navarra Hospital Complex, Pamplona, Spain

Search for other papers by María Malumbres-Chacon in
Google Scholar
PubMed Close
,
Lotfi Ahmed-Mohamed Department of Pediatrics, Navarra Hospital Complex, Pamplona, Spain

Search for other papers by Lotfi Ahmed-Mohamed in
Google Scholar
PubMed Close
,
María Jesús Chueca -Guindulain Department of Pediatrics, Navarra Hospital Complex, Pamplona, Spain
Navarra Institute for Health Research (IdisNA), Pamplona, Spain

Search for other papers by María Jesús Chueca -Guindulain in
Google Scholar
PubMed Close
, and
Sara Berrade-Zubiri Department of Pediatrics, Navarra Hospital Complex, Pamplona, Spain
Navarra Institute for Health Research (IdisNA), Pamplona, Spain

Search for other papers by Sara Berrade-Zubiri in
Google Scholar
PubMed Close

Introduction Central precocious puberty (CPP) is defined as the premature activation of the hypothalamic–pituitary–gonadal axis (HPG) with the onset of breast development before 8 years of age in girls and an increase in testicular size in

Article Type:
Research Article
Collections:
Paediatric Endocrinology Collection
DOI:
https://doi.org/10.1530/EC-20-0651
Volume/Issue:
Volume 10: Issue 2
Open access
Enora Le Roux Université de Paris, ECEVE UMR 1123, Inserm, Paris, France
AP-HP.Nord-Université de Paris, Hôpital Universitaire Robert Debré, Unité d’Épidémiologie Clinique, Inserm, Paris, France

Search for other papers by Enora Le Roux in
Google Scholar
PubMed Close
,
Florence Menesguen AP-HP. Sorbonne Université, Hôpital Universitaire Pitié Salpêtrière-Charles Foix, Service d’Endocrinologie et Médecine de la Reproduction, Centre de Maladies Endocriniennes Rares de la Croissance et du Développement, Centre de Pathologies Gynécologiques Rares, Paris, France

Search for other papers by Florence Menesguen in
Google Scholar
PubMed Close
,
Isabelle Tejedor AP-HP. Sorbonne Université, Hôpital Universitaire Pitié Salpêtrière-Charles Foix, Service d’Endocrinologie et Médecine de la Reproduction, Centre de Maladies Endocriniennes Rares de la Croissance et du Développement, Centre de Pathologies Gynécologiques Rares, Paris, France

Search for other papers by Isabelle Tejedor in
Google Scholar
PubMed Close
,
Marc Popelier AP-HP. Sorbonne Université, Hôpital Universitaire Pitié Salpêtrière-Charles Foix, Service de Diabétologie, Paris, France

Search for other papers by Marc Popelier in
Google Scholar
PubMed Close
,
Marine Halbron AP-HP. Sorbonne Université, Hôpital Universitaire Pitié Salpêtrière-Charles Foix, Service de Diabétologie, Paris, France

Search for other papers by Marine Halbron in
Google Scholar
PubMed Close
,
Pauline Faucher AP-HP. Sorbonne Université, Hôpital Universitaire Pitié Salpêtrière-Charles Foix, Service de Nutrition, Centre du Syndrome de Prader-Willi et Autres Obésités Rares, Paris, France

Search for other papers by Pauline Faucher in
Google Scholar
PubMed Close
,
Sabine Malivoir AP-HP. Sorbonne Université, Hôpital Universitaire Pitié Salpêtrière-Charles Foix, Service d’Endocrinologie et Médecine de la Reproduction, Centre de Maladies Endocriniennes Rares de la Croissance et du Développement, Centre de Pathologies Gynécologiques Rares, Paris, France

Search for other papers by Sabine Malivoir in
Google Scholar
PubMed Close
,
Graziella Pinto AP-HP.Université de Paris Centre, Hôpital Universitaire Necker Enfants Malades, Département d’Endocrinologie, Diabétologie et Gynécologie Pédiatrique, Paris, France; Centre de Maladies Endocriniennes Rares de la Croissance et du Développement, Centre de Pathologies Gynécologiques Rares, Paris, France

Search for other papers by Graziella Pinto in
Google Scholar
PubMed Close
,
Juliane Léger AP-HP.Nord-Université de Paris, Hôpital Universitaire Robert Debré, Service d’Endocrinologie Diabétologie Pédiatrique, Centre de Référence des Maladies Endocriniennes de la Croissance et du Développement, Paris, France

Search for other papers by Juliane Léger in
Google Scholar
PubMed Close
,
Stephane Hatem Institute of Cardiology and Nutrition, Paris, France

Search for other papers by Stephane Hatem in
Google Scholar
PubMed Close
,
Michel Polak AP-HP.Université de Paris Centre, Hôpital Universitaire Necker Enfants Malades, Département d’Endocrinologie, Diabétologie et Gynécologie Pédiatrique, Paris, France; Centre de Maladies Endocriniennes Rares de la Croissance et du Développement, Centre de Pathologies Gynécologiques Rares, Paris, France

Search for other papers by Michel Polak in
Google Scholar
PubMed Close
,
Christine Poitou AP-HP. Sorbonne Université, Hôpital Universitaire Pitié Salpêtrière-Charles Foix, Service de Nutrition, Centre du Syndrome de Prader-Willi et Autres Obésités Rares, Paris, France

Search for other papers by Christine Poitou in
Google Scholar
PubMed Close
, and
Philippe Touraine AP-HP. Sorbonne Université, Hôpital Universitaire Pitié Salpêtrière-Charles Foix, Service d’Endocrinologie et Médecine de la Reproduction, Centre de Maladies Endocriniennes Rares de la Croissance et du Développement, Centre de Pathologies Gynécologiques Rares, Paris, France

Search for other papers by Philippe Touraine in
Google Scholar
PubMed Close

this context that a new programme of transition based on case management has been developed in a French adult hospital for young people with various endocrine and metabolic diseases. The development project was based on a survey, conducted by the team

Article Type:
Research Article
Collections:
Paediatric Endocrinology Collection
DOI:
https://doi.org/10.1530/EC-20-0520
Volume/Issue:
Volume 10: Issue 1
Open access
Mei Li Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

Search for other papers by Mei Li in
Google Scholar
PubMed Close
,
Yanfei Chen Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

Search for other papers by Yanfei Chen in
Google Scholar
PubMed Close
,
Binrong Liao Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

Search for other papers by Binrong Liao in
Google Scholar
PubMed Close
,
Jing Tang Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

Search for other papers by Jing Tang in
Google Scholar
PubMed Close
,
Jingzi Zhong Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

Search for other papers by Jingzi Zhong in
Google Scholar
PubMed Close
, and
Dan Lan Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

Search for other papers by Dan Lan in
Google Scholar
PubMed Close

luteinizing hormone (LH) and follicle stimulating hormone (FSH). Central precocious puberty (CPP) is a common pediatric endocrine disease due to premature reactivation of the HPG axis leading to the development of secondary sexual characteristics before the

Article Type:
Research Article
Collections:
Paediatric Endocrinology Collection
DOI:
https://doi.org/10.1530/EC-21-0182
Volume/Issue:
Volume 10: Issue 9
Open access
Raja Padidela Royal Manchester Children’s Hospital and Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK

Search for other papers by Raja Padidela in
Google Scholar
PubMed Close
,
Moira S Cheung Evelina London Children’s Hospital, London, UK

Search for other papers by Moira S Cheung in
Google Scholar
PubMed Close
,
Vrinda Saraff Birmingham Women’s and Children’s Hospital, Birmingham, UK

Search for other papers by Vrinda Saraff in
Google Scholar
PubMed Close
, and
Poonam Dharmaraj Alder Hey Children’s NHS Foundation Trust, Liverpool, UK

Search for other papers by Poonam Dharmaraj in
Google Scholar
PubMed Close

monitor development and progression of nephrocalcinosis. On an annual basis, blood pressure should be checked. A clinical assessment of skeletal deformity, including craniosynostosis when age appropriate, should also be made at every clinic visit and, if

Article Type:
Research Article
Collections:
Paediatric Endocrinology Collection
DOI:
https://doi.org/10.1530/EC-20-0291
Volume/Issue:
Volume 9: Issue 10
Open access