Division of Endocrinology, Division of Nephrology, Endocrine Research Laboratory, Department of Medicine
Division of Endocrinology, Division of Nephrology, Endocrine Research Laboratory, Department of Medicine
Division of Endocrinology, Division of Nephrology, Endocrine Research Laboratory, Department of Medicine
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are significant similarities between the morbidity of Cushing's syndrome and renal failure (8, 9) . Thus, it is important to be able to properly assess the HPA axis in ESRD subjects. The current study was designed to evaluate the circadian rhythm of
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the biological clock oscillators, the pineal gland secretes melatonin into the blood with high level during the subjective night and low level during the subjective day ( 2 ) and is a typical model system for the study of circadian rhythm. Melatonin
Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
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Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
Department of Nursing Physiotherapy and Medicine, SPORT Research Group (CTS-1024), CERNEP Research Center, University of Almería, Almería, Spain
Biomedical Research Unit, Torrecárdenas University Hospital, Almería, Spain
CIBER de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Granada, Spain
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Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
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Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
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Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
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Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
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Department of Medicine, Huddinge, Karolinska Institutet Campus Flemingsberg, Neo Building, Huddinge, Sweden
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Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
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Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
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characteristics of this cohort has been extensively described elsewhere ( 12 ). To study the influence of circadian rhythm on cold-induced changes in serum GDF15 and FGF21 levels, a general linear model with repeated measures was used, with two within
Department of Physiology and Pharmacology V. Erspamer, Sapienza University of Rome, Rome, Italy
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that the exposure to EE ( 25 ) or to the odour of a phobic stimulus such as predator scent ( 26 ) induces an increase of plasma corticosterone concentrations in rats. We also assessed FCM circadian rhythm in socially isolated male and female rats in
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the male Sprague–Dawley rat . Chronobiology International 1993 10 244 – 258 . ( doi:10.1080/07420529309059707 ) 14 Meier AH Cincotta AH. Circadian rhythms regulate the- expression of the thrifty genotype/phenotype . Diabetes Reviews
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observed in control mice ( 57 ). This change in the circadian rhythm of feeding correlated with similar changes in physical activity and energy expenditure. These results suggested a critical role for Kiss1 ARC neurons in the regulation of circadian
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Department of Clinical Biochemistry (KB3014), Department of Technology, Department of Clinical Biochemistry, Department of Biomedical Sciences, Department of Clinical Medicine, Rigshospitalet, University of Copenhagen, 9 Blegdamsvej, DK-2100 Copenhagen, Denmark
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Department of Clinical Biochemistry (KB3014), Department of Technology, Department of Clinical Biochemistry, Department of Biomedical Sciences, Department of Clinical Medicine, Rigshospitalet, University of Copenhagen, 9 Blegdamsvej, DK-2100 Copenhagen, Denmark
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regulation of energy metabolism . Nature Reviews. Endocrinology 2014 10 157 – 163 . ( doi:10.1038/nrendo.2013.234 ). 8 Bray MS Young ME . Circadian rhythms in the development of obesity: potential role for the circadian
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Department of Clinical Biochemistry, Imperial College Healthcare NHS Trust, London, UK
Department of Investigative Medicine, Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK
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Department of Investigative Medicine, Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK
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profile with oral medication is a significant challenge because normal cortisol production is pulsatile and consists of a circadian rhythm and an ultradian rhythm ( 3 , 4 , 5 ). Under-replacement may cause lethargy and an increased risk of Addisonian
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
Department of Clinical Biochemistry, North West London Pathology, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
Department of Clinical Biochemistry, North West London Pathology, London, UK
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patients take prednisolone as early as possible upon wakening. Other studies are trialling glucocorticoid pump replacement therapy to mimic circadian rhythms; however, there is limited evidence for their use so far ( 24 , 25 ). The importance of pulsatile
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has been heavily studied ( 2 ). Serum levels of hGH vary considerably over the course of the day and during the night as it is dependent on a variety of factors including (and not limited to) the circadian rhythm, sleep–wake cycle, diet, metabolism