Search for other papers by Leqi He in
Google Scholar
PubMed
Search for other papers by Xiaoying Li in
Google Scholar
PubMed
Search for other papers by Zaoping Chen in
Google Scholar
PubMed
Search for other papers by Wei Wang in
Google Scholar
PubMed
Search for other papers by Kai Wang in
Google Scholar
PubMed
Search for other papers by Xinmei Huang in
Google Scholar
PubMed
Search for other papers by Qian Yang in
Google Scholar
PubMed
Search for other papers by Wencai Ke in
Google Scholar
PubMed
Search for other papers by Jun Liu in
Google Scholar
PubMed
Search for other papers by Bingbing Zha in
Google Scholar
PubMed
protein kinase A (p-PKA) and phosphorylated versions of cAMP response element-binding protein (p-CREB) were purchased from Cell Signaling Technology. The antibodies against NIS were purchased from Proteintech (Chicago, IL, USA). Reverse transcription
Search for other papers by Giuseppe Lisco in
Google Scholar
PubMed
Search for other papers by Anna De Tullio in
Google Scholar
PubMed
Search for other papers by Olga Disoteo in
Google Scholar
PubMed
Search for other papers by Giuseppina Piazzolla in
Google Scholar
PubMed
Search for other papers by Edoardo Guastamacchia in
Google Scholar
PubMed
Search for other papers by Carlo Sabbà in
Google Scholar
PubMed
Search for other papers by Vincenzo De Geronimo in
Google Scholar
PubMed
Search for other papers by Enrico Papini in
Google Scholar
PubMed
Search for other papers by Vincenzo Triggiani in
Google Scholar
PubMed
conditions. It also stimulates the synthesis and secretion of calcitonin in a cAMP-dependent manner. Therefore, GLP-1 may promote rodent thyroid carcinogenesis ( 10 ), but insufficient evidence indicates the potential cancerogenic effect in humans ( 11 , 12
Search for other papers by Caiyan Mo in
Google Scholar
PubMed
Search for other papers by Tao Tong in
Google Scholar
PubMed
Search for other papers by Ying Guo in
Google Scholar
PubMed
Search for other papers by Zheng Li in
Google Scholar
PubMed
Search for other papers by Liyong Zhong in
Google Scholar
PubMed
ability of the patient's IgG to block TSH binding and induce the production of cyclic adenosine monophosphate (cAMP), and the activity index and symptom of GD improved after surgical remission of acromegaly, confirming the hypothesis that the GH−IGF-1 axis
Department of Diabetes & Endocrinology, Skåne University Hospital, Malmö, Sweden
Search for other papers by Bushra Shahida in
Google Scholar
PubMed
Department of Diabetes & Endocrinology, Skåne University Hospital, Malmö, Sweden
Search for other papers by Tereza Planck in
Google Scholar
PubMed
Search for other papers by Tania Singh in
Google Scholar
PubMed
Department of Ophthalmology, Skåne University Hospital, Malmö, Sweden
Search for other papers by Peter Åsman in
Google Scholar
PubMed
Department of Diabetes & Endocrinology, Skåne University Hospital, Malmö, Sweden
Search for other papers by Mikael Lantz in
Google Scholar
PubMed
subsequently activating adenylate cyclase. This activation leads to the generation of cyclic adenosine monophosphate (cAMP). Elevated levels of cAMP induce the proliferation of thyrocytes, thereby fostering thyroid growth and the secretion of thyroid hormones T
Search for other papers by Weiwei Liang in
Google Scholar
PubMed
Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
Search for other papers by Yilin Zhang in
Google Scholar
PubMed
Search for other papers by Yan Guo in
Google Scholar
PubMed
Search for other papers by Pengyuan Zhang in
Google Scholar
PubMed
Search for other papers by Jiewen Jin in
Google Scholar
PubMed
Search for other papers by Hongyu Guan in
Google Scholar
PubMed
Search for other papers by Yanbing Li in
Google Scholar
PubMed
relationship between FLNA expression and PTC patients’ prognosis. After using an X-tile (Robert L Camp, Yale University, New Haven, CT, USA) for separating patients into high or low FLNA expressions, the Kaplan–Meier curve methods were applied to produce
Search for other papers by Qian Yang in
Google Scholar
PubMed
Search for other papers by Wencai Ke in
Google Scholar
PubMed
Search for other papers by Fanfan Pan in
Google Scholar
PubMed
Search for other papers by Xinmei Huang in
Google Scholar
PubMed
Search for other papers by Jun Liu in
Google Scholar
PubMed
Search for other papers by Bingbing Zha in
Google Scholar
PubMed
number of factors. TSH binds TSHR to activate CREB phosphorylation of the cAMP pathway ( 13 , 14 ), which can bind to the upstream enhancer region of the NIS gene to promote NIS expression ( 15 ). In addition, many inflammatory factors such as
Search for other papers by Huixing Liu in
Google Scholar
PubMed
Search for other papers by Daoquan Peng in
Google Scholar
PubMed
and activity of HMGCR through the cAMP/PKA/CREB signaling pathway ( 49 ). TSH can also stimulate the expression of SREBP2 to regulate HMGCR ( 35 , 50 ). In adipocytes, TSHβ elevates HMGCR mRNA levels, and TSHβ expression levels in mice’s s
Search for other papers by Hui Li in
Google Scholar
PubMed
Search for other papers by Peng Wu in
Google Scholar
PubMed
methylation and transcriptome-related genes in thyroid carcinoma . Cancers 2022 14 . ( https://doi.org/10.3390/cancers14051163 ) 38 Yu Q Gong X Tong Y Wang M Duan K Zhang X Ge F Yu X & Li S . Phosphorylation of Jhd2 by the Ras-cAMP