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Functional hypogonadism in adolescence: an overlooked cause of secondary hypogonadism

Rebeca Esquivel-Zuniga

Rebeca Esquivel-Zuniga Department of Pediatrics, University of Virginia, Charlottesville, Virginia, USA

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Alan D Rogol

Alan D Rogol Department of Pediatrics, University of Virginia, Charlottesville, Virginia, USA

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, inhibition of gonadotropin production/secretion, inhibition of steroidogenesis, increase in testosterone metabolism, oxidative stress and induction of apoptosis. AAS, anabolic–androgenic steroids; FSH, follicle-stimulating hormone; GnRH, gonadotropin