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considered; the receptor is regulated by E2, and clinical studies have shown it to be a protective factor ( 34 ). In addition, progesterone in vitro reduces cell number and increases apoptosis in ovarian cancer cells ( 35 , 36 ). There is also a need to
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limited. Menin and NFκB NFκB is a transcription factor that functions as an important regulator of apoptosis and proto-oncogene. In intact cells, NFκB is predominantly localized in the cytoplasm in an inactive form, bound to the inhibitor protein IkB
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. Thyroid hormone, cancer, and apoptosis . Comprehensive Physiology 2016 6 1221 – 1237 . ( https://doi.org/10.1002/cphy.c150035 ) 23 Leopoldo S Lorena B Cinzia A Gabriella DC Angela Luciana B Renato C Antonio M Carlo S Cristina P Stefano