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Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy
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Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy
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Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy
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, secreted by adipocytes, acts as a permissive stimulus on GnRH pulsatile secretion ( 33 , 34 ). On the contrary, adiponectin inhibits GnRH release resulting in a delayed onset of puberty. TNF-α and IL-6 inhibit the production of adiponectin