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Huiyuan Zhai
Huiyuan Zhai
Department of Pharmacy, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China
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Dongxu Wang
Dongxu Wang
Department of Geriatrics, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China
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Yong Wang
Yong Wang
Department of Pharmacy, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China
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Hongwei Gu
Hongwei Gu
Central Laboratory, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China
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Juan Jv
Juan Jv
Department of Cardiology, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China
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Liangliang Yuan
Liangliang Yuan
Department of Pharmacy, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China
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Chao Wang
Chao Wang
Department of Pharmacy, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China
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Leiyao Chen
Leiyao Chen
Department of Pharmacy, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China
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classified into two main phenotypes: classical M1 macrophages and alternatively activated macrophages M2. Although both M1 and M2 macrophages increase in adipose tissue during expansion, M1 macrophages tend to dominate, aggregating around apoptotic adipocytes
Yi Jia
Yi Jia
School of Health and Exercise, The Key Laboratory of Exercise and Health Sciences of Ministry of Education, Shanghai University of Sport, Shanghai, China
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Yanan Yang
Yanan Yang
School of Health and Exercise, The Key Laboratory of Exercise and Health Sciences of Ministry of Education, Shanghai University of Sport, Shanghai, China
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Jing Qu
Jing Qu
School of Health and Exercise, The Key Laboratory of Exercise and Health Sciences of Ministry of Education, Shanghai University of Sport, Shanghai, China
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Lijun Yin
Lijun Yin
School of Health and Exercise, The Key Laboratory of Exercise and Health Sciences of Ministry of Education, Shanghai University of Sport, Shanghai, China
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Xiaohui Wang
Xiaohui Wang
School of Health and Exercise, The Key Laboratory of Exercise and Health Sciences of Ministry of Education, Shanghai University of Sport, Shanghai, China
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= 4 mice/group. * P < 0.05, ** P < 0.01 vs WT. WT, wild-type mice; WT + EX, WT + exercise; chemerin (−/−), chemerin knockout mice; chemerin (−/−) + EX, chemerin (−/−) + exercise. Chemerin knockout lowered the adipocyte size of
Jing Li
Jing Li
School of Physical Education, Liaoning Normal University, Dalian, Liaoning, China
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Xuejie Yi
Xuejie Yi
Exercise and Health Research Center, Department of Kinesiology, Laboratory Management Center, Shenyang Sport University, Shenyang, Liaoning, China
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Tao Li
Tao Li
Exercise and Health Research Center, Department of Kinesiology, Laboratory Management Center, Shenyang Sport University, Shenyang, Liaoning, China
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Tingting Yao
Tingting Yao
School of Physical Education, Liaoning Normal University, Dalian, Liaoning, China
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Dongyang Li
Dongyang Li
Exercise and Health Research Center, Department of Kinesiology, Laboratory Management Center, Shenyang Sport University, Shenyang, Liaoning, China
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Guangxuan Hu
Guangxuan Hu
Exercise and Health Research Center, Department of Kinesiology, Laboratory Management Center, Shenyang Sport University, Shenyang, Liaoning, China
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Yongqi Ma
Yongqi Ma
Exercise and Health Research Center, Department of Kinesiology, Laboratory Management Center, Shenyang Sport University, Shenyang, Liaoning, China
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Bo Chang
Bo Chang
Exercise and Health Research Center, Department of Kinesiology, Laboratory Management Center, Shenyang Sport University, Shenyang, Liaoning, China
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Shicheng Cao
Shicheng Cao
Department of Sports Medicine, School of Public and Basic Sciences, China Medical University, Shenyang, Liaoning, China
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into a new type of adipocytes, beige adipocytes ( 2 , 3 ), which have a similar thermogenic function to that of BAT. Increased thermogenesis in skeletal muscle caused by exercise is related to peroxisome proliferator-activated receptor-gamma co
Yunyi Ding
Yunyi Ding
Department of Nephrology, Hangzhou TCM Hospital of Zhejiang Chinese Medical University, Hangzhou, China
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Siyao Lv
Siyao Lv
Department of Gastroenterology, Hangzhou TCM Hospital of Zhejiang Chinese Medical University, Hangzhou, China
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Ruijie Xie
Ruijie Xie
Division of Clinical Epidemiology and Aging Research, University of Heidelberg, Heidelberg, Germany
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Wei Ye
Wei Ye
Department of Gastroenterology, Hangzhou TCM Hospital, Hangzhou, China
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Yichen Luo
Yichen Luo
School of Mechanical Engineering, Zhejiang University, Hangzhou, China
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Yayu Li
Yayu Li
Department of Nephrology, Hangzhou TCM Hospital, Hangzhou, China
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adipocytes play an important role in the pathogenesis of DKD. A variety of adipokines secreted by adipocytes, such as adiponectin, leptin, resistin, visfatin, and chemerin, are related to the progression of DKD. Adiponectin is considered to have a
Marenao Tana
Marenao Tana
Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan
Tanaka Medical Clinic, Yoichi, Japan
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Tanaka Medical Clinic, Yoichi, Japan
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Tomohito Gohda
Tomohito Gohda
Department of Nephrology, Juntendo University Faculty of Medicine, Tokyo, Japan
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Nozomu Kamei
Nozomu Kamei
Department of Endocrinology and Metabolism, Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital, Hiroshima, Japan
Institute for Clinical Research, NHO Kure Medical Center and Chugoku Cancer Center, Hiroshima, Japan
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Institute for Clinical Research, NHO Kure Medical Center and Chugoku Cancer Center, Hiroshima, Japan
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Maki Murakoshi
Maki Murakoshi
Department of Nephrology, Juntendo University Faculty of Medicine, Tokyo, Japan
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Tatsuya Sato
Tatsuya Sato
Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan
Department of Cellular Physiology and Signal Transduction, Sapporo Medical University School of Medicine, Sapporo, Japan
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Department of Cellular Physiology and Signal Transduction, Sapporo Medical University School of Medicine, Sapporo, Japan
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Mitsunobu Kubota
Mitsunobu Kubota
Department of Endocrinology and Diabetology, NHO Kure Medical Center and Chugoku Cancer Center, Hiroshima, Japan
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Michiyoshi Sanuki
Michiyoshi Sanuki
Institute for Clinical Research, NHO Kure Medical Center and Chugoku Cancer Center, Hiroshima, Japan
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Erika Ishiwata
Erika Ishiwata
Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan
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Keisuke Endo
Keisuke Endo
Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan
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Yusuke Suzuki
Yusuke Suzuki
Department of Nephrology, Juntendo University Faculty of Medicine, Tokyo, Japan
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Masato Furuhashi
Masato Furuhashi
Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan
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). Fatty acid-binding protein 4 (FABP4) is expressed in adipocytes, macrophages, and capillary and injured arterial endothelial cells, and excessive expression of FABP4 is associated with the development of insulin resistance and atherosclerosis, leading to
Katrine M Lauritsen
Katrine M Lauritsen
Steno Diabetes Center Aarhus, Aarhus, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Danish Diabetes Academy, Odense University Hospital, Odense, Denmark
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Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Danish Diabetes Academy, Odense University Hospital, Odense, Denmark
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Jens Hohwü Voigt
Jens Hohwü Voigt
Steno Diabetes Center Aarhus, Aarhus, Denmark
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Steen Bønløkke Pedersen
Steen Bønløkke Pedersen
Steno Diabetes Center Aarhus, Aarhus, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
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Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
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Troels K Hansen
Troels K Hansen
Steno Diabetes Center Aarhus, Aarhus, Denmark
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Niels Møller
Niels Møller
Steno Diabetes Center Aarhus, Aarhus, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
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Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
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Niels Jessen
Niels Jessen
Steno Diabetes Center Aarhus, Aarhus, Denmark
Department of Biomedicine, Aarhus University, Aarhus, Denmark
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Department of Biomedicine, Aarhus University, Aarhus, Denmark
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Lars C Gormsen
Lars C Gormsen
Department of Nuclear Medicine and PET Centre, Aarhus University Hospital, Aarhus, Denmark
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Esben Søndergaard
Esben Søndergaard
Steno Diabetes Center Aarhus, Aarhus, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Danish Diabetes Academy, Odense University Hospital, Odense, Denmark
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Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Danish Diabetes Academy, Odense University Hospital, Odense, Denmark
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circulating ketone bodies which inhibit lipolysis through metabolite-sensing G-coupled receptors on adipocytes ( 3 , 9 ). In addition to the effects on lipolysis, reduced insulin concentrations could also affect lipid storage through its regulating effects on
Philippe Jean-Luc Gradidge
Philippe Jean-Luc Gradidge
Centre for Exercise Science and Sports Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
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Nicole G Jaff
Nicole G Jaff
Department of Chemical Pathology, National Health Laboratory Service, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
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Shane A Norris
Shane A Norris
SAMRC/Wits Developmental Pathways for Health Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Global Health Research Institute, School of Human Development and Health, University of Southampton, Southampton, UK
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Global Health Research Institute, School of Human Development and Health, University of Southampton, Southampton, UK
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Marketa Toman
Marketa Toman
Department of Chemical Pathology, National Health Laboratory Service, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
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Nigel J Crowther
Nigel J Crowther
Department of Chemical Pathology, National Health Laboratory Service, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
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fat mass causes adiponectin levels to rise, are not known. The physiological purpose of these opposing influences on adiponectin secretion is also not fully understood. Studies have shown that a number of factors do affect adipocyte secretion of
Xiaobing Lu
Xiaobing Lu
Department of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Jiang Yue
Jiang Yue
Department of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Qianjing Liu
Qianjing Liu
Department of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Shengyun He
Shengyun He
Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Ying Dong
Ying Dong
Department of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Ming Zhang
Ming Zhang
Department of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Yicheng Qi
Yicheng Qi
Department of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Minglan Yang
Minglan Yang
Department of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Wang Zhang
Wang Zhang
Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Hua Xu
Hua Xu
Department of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Qing Lu
Qing Lu
Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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Jing Ma
Jing Ma
Department of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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between human adipocytes and skeletal muscle cells. IMAT is characterized by a highly immunogenic and inflammatory secretome, associated with inflammatory cytokines, extracellular matrix proteins and increasing interstitial free fatty acid (FFA) levels in
Wang-shu Liu
Wang-shu Liu
Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China
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Ling-yan Hua
Ling-yan Hua
Department of Ophthalmology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China
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Su-xiang Zhu
Su-xiang Zhu
Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China
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Feng Xu
Feng Xu
Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China
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Xue-qin Wang
Xue-qin Wang
Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China
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Chun-feng Lu
Chun-feng Lu
Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China
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Jian-bin Su
Jian-bin Su
Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China
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Feng Qi
Feng Qi
Emergency Intensive Care Unit, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China
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( 13 ) and mediating insulin desensitization in adipocytes ( 14 ). Our previous study demonstrated that serum SDF-1 levels are closely related to hyperglycemia, hypercoagulability, and inflammation in patients with T2D ( 15 ). Since chronic
Chengnan Guo
Chengnan Guo
Division of Epidemiology and Health Statistics, Department of Preventive Medicine, School of Public Health & Management, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Yixi Xu
Yixi Xu
Division of Epidemiology and Health Statistics, Department of Preventive Medicine, School of Public Health & Management, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Yange Ma
Yange Ma
Division of Epidemiology and Health Statistics, Department of Preventive Medicine, School of Public Health & Management, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Xin Xu
Xin Xu
Wenzhou Medical University, Wenzhou, Zhejiang, China
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Fang Peng
Fang Peng
Division of Epidemiology and Health Statistics, Department of Preventive Medicine, School of Public Health & Management, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Hui-hui Li
Hui-hui Li
Division of Epidemiology and Health Statistics, Department of Preventive Medicine, School of Public Health & Management, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Dongzhen Jin
Dongzhen Jin
Division of Epidemiology and Health Statistics, Department of Preventive Medicine, School of Public Health & Management, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Shu-zhen Zhao
Shu-zhen Zhao
Division of Epidemiology and Health Statistics, Department of Preventive Medicine, School of Public Health & Management, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Zhezheng Xia
Zhezheng Xia
Division of Epidemiology and Health Statistics, Department of Preventive Medicine, School of Public Health & Management, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Mengyuan Lai
Mengyuan Lai
Division of Epidemiology and Health Statistics, Department of Preventive Medicine, School of Public Health & Management, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Mingzhu Che
Mingzhu Che
Division of Epidemiology and Health Statistics, Department of Preventive Medicine, School of Public Health & Management, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Ruogu Huang
Ruogu Huang
Division of Epidemiology and Health Statistics, Department of Preventive Medicine, School of Public Health & Management, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Yanan Wang
Yanan Wang
Division of Epidemiology and Health Statistics, Department of Preventive Medicine, School of Public Health & Management, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Depeng Jiang
Depeng Jiang
Department of Community Health Sciences, College of Medicine, University of Manitoba, Winnipeg, Canada
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Chao Zheng
Chao Zheng
The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
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Guangyun Mao
Guangyun Mao
Division of Epidemiology and Health Statistics, Department of Preventive Medicine, School of Public Health & Management, Wenzhou Medical University, Wenzhou, Zhejiang, China
Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China
National Clinical Research Center for Ocular Diseases, Wenzhou, Zhejiang, China
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Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China
National Clinical Research Center for Ocular Diseases, Wenzhou, Zhejiang, China
Search for other papers by Guangyun Mao in
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PubMed
suppresses mesenteric adipocyte hypertrophy, declines damaged glucose tolerance during the oral glucose tolerance test, and mitigates insulin resistance in both metabolic syndrome and obese mouse models ( 15 , 33 ). Available evidence reports that TREH may
