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Anna Gorbacheva
Anna Gorbacheva
Endocrinology Research Center, Moscow, Russian Federation
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Anna Eremkina
Anna Eremkina
Endocrinology Research Center, Moscow, Russian Federation
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Daria Goliusova
Daria Goliusova
Endocrinology Research Center, Moscow, Russian Federation
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Julia Krupinova
Julia Krupinova
Endocrinology Research Center, Moscow, Russian Federation
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Natalia Mokrysheva
Natalia Mokrysheva
Endocrinology Research Center, Moscow, Russian Federation
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), where it is responsible for the conversion of osteoblasts into adipocyte-like cells ( 63 , 64 ) and their differentiation ( 65 ). Different PPARγ ligands can affect bone metabolism; for example, rosiglitazone inhibits the expression of Runx2/Cba1, the
Vita Birzniece
Vita Birzniece
School of Medicine, Western Sydney University, New South Wales, Australia
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Garvan Institute of Medical Research, New South Wales, Australia
School of Medical Sciences, University of New South Wales, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Garvan Institute of Medical Research, New South Wales, Australia
School of Medical Sciences, University of New South Wales, New South Wales, Australia
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Teresa Lam
Teresa Lam
School of Medicine, Western Sydney University, New South Wales, Australia
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Department of Diabetes and Endocrinology, Westmead Hospital, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Department of Diabetes and Endocrinology, Westmead Hospital, New South Wales, Australia
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Mark McLean
Mark McLean
School of Medicine, Western Sydney University, New South Wales, Australia
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
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Navneeta Reddy
Navneeta Reddy
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
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Haleh Shahidipour
Haleh Shahidipour
School of Medicine, Western Sydney University, New South Wales, Australia
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
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Amy Hayden
Amy Hayden
School of Medicine, Western Sydney University, New South Wales, Australia
Faculty of Medicine, Health and Human Sciences, Macquarie University, New South Wales, Australia
Crown Princess Mary Cancer Centre, Westmead Hospital, New South Wales, Australia
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Faculty of Medicine, Health and Human Sciences, Macquarie University, New South Wales, Australia
Crown Princess Mary Cancer Centre, Westmead Hospital, New South Wales, Australia
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Howard Gurney
Howard Gurney
Crown Princess Mary Cancer Centre, Westmead Hospital, New South Wales, Australia
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Glenn Stone
Glenn Stone
School of Computing, Engineering and Mathematics, Western Sydney University, New South Wales, Australia
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Rikke Hjortebjerg
Rikke Hjortebjerg
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
Steno Diabetes Center Odense, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
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Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
Steno Diabetes Center Odense, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
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Jan Frystyk
Jan Frystyk
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
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Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
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protein synthesis in muscle ( 73 ). In adipocytes, IGF-1R activation stimulates glucose uptake. This is likely to occur also in brown fat cells, where IGF-1R activation has been shown to be essential for full thermogenic capacity ( 74 ). The increase in
