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Division of Endocrinology, Mid and South Essex NHS Trust, Broomfield, UK
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Introduction Coronavirus disease 2019 (COVID19) is a multisystem disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and has been a major public health challenge across the globe since its emergence in late 2019. The
Department of Clinical Research, University of Basel, Basel, Switzerland
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Department of Clinical Research, University of Basel, Basel, Switzerland
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Department of Clinical Research, University of Basel, Basel, Switzerland
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University Center of Cardiovascular Science & Department of Cardiology, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
German Center for Cardiovascular Research (DZHK), Partner Site Hamburg–Kiel–Lübeck, Hamburg, Germany
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. Methods Study design and participants This prospective, observational cohort study included consecutively enrolled patients aged 18 years and older presenting with clinically suspected or confirmed SARS-CoV-2 infection to the Emergency Department (ED
Department of Infectious Diseases, Copenhagen University Hospital – Amager and Hvidovre, Hvidovre, Denmark
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Centre for Physical Activity Research, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
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Centre for Physical Activity Research, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
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Centre for Physical Activity Research, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Center for Clinical Research and Prevention, Copenhagen University Hospital – Bispebjerg and Frederiksberg, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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cohort) were included. The two cohorts were separated by those who were introduced to remdesivir and dexamethasone as standard-of-care. Inclusion criteria for patients with COVID-19 were (i) presence of SARS-CoV-2 RNA confirmed by reverse
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in both groups. Furthermore, we have previously shown no difference in the prevalence of anti-SARS-CoV-2 IgM and IgG antibody positivity between IGHD subjects and matched normal stature individuals in October 2020, during the acceleration of the
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Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy
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Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy
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Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy
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years in males, equivalent to 2 s.d. below the mean age at the onset of puberty ( 16 ). At the end of 2019, a novel coronavirus identified as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing atypical pneumonia defined as