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glucose values (2h-PG) after 75 g oral glucose tolerance test (OGTT) levels between 7.8 and 11.0 mmol/L. However, the World Health Organization (WHO) and numerous other diabetes organizations define the IFG cutoff at 6.1 mmol/L ( 8 ). Additionally, ADA
International Research and Research Training Center in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen, Denmark
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The Child and Youth Clinic, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Research and Research Training Center in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen, Denmark
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International Research and Research Training Center in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen, Denmark
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International Research and Research Training Center in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen, Denmark
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lipids, leptin and adiponectin levels as well as to glucose and insulin levels during a two-h oral glucose tolerance test (OGTT). Methods Participants Subjects were recruited as part of the Copenhagen Puberty Study ( 15 , 16 ) from primary
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark
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Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Endocrinology and Nephrology, Nordsjællands University Hospital, Hillerød, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
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Steno Diabetes Center Copenhagen, Gentofte, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
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Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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D) (confirmed C-peptide negative and, therefore, without residual insulin secretion) and from healthy individuals during an oral glucose tolerance test (OGTT) and during an isoglycemic i.v. glucose infusion (IIGI), respectively. Secondly, in order to
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optimal method to detect potential dysglycemia ( 12 ). Moreover, the most accurate means for testing hyperglycemia including fasting plasma glucose (FPG), oral glucose tolerance test (OGTT), or hemoglobin A1c (HbA1c) has to be clarified ( 13 ). Several
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). Nevertheless, the time-consuming and labor-intensive feature of this technique limits its routine use. Instead, based on the indices from oral glucose tolerance test (OGTT), several mathematical models have been developed to generate indices that correlate well
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through the measurement of fasting plasma glucose (PG) and, if this result was normal, between the 24th and 28th weeks of gestation with the 75-g 2-h oral glucose tolerance test (OGTT). In this study, the GDM diagnosis was established in the presence of
University of Belgrade, Medical Faculty, Belgrade, Serbia
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Insitute of Medical Statistics and Informatics, Belgrade, Serbia
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tolerance test (OGTT, nadir >1.0 ng/mL) and elevated IGF-1 (above age-related reference range). Active acromegaly was excluded by suppressible GH in OGTT <1.0 ng/mL ( 29 ). All subjects were assessed by a physical examination and routine biochemical analysis
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Department of Medicine, Gentofte and Herlev Hospital, University of Copenhagen, Denmark
Steno Diabetes Center Copenhagen, Gentofte, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Center for Cancer and Organ Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Novartis Healthcare A/S, Copenhagen, Denmark
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Department of Medicine, Gentofte and Herlev Hospital, University of Copenhagen, Denmark
Novartis Healthcare A/S, Copenhagen, Denmark
Department of Nephrology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Subjects One hundred and four participants (34 females) from 8 separate studies in which the incretin effect had been investigated using OGTTs and IIGIs were included in the present study ( 4 , 34 , 36 , 37 , 38 , 39 , 40 , 41 ). Only individuals
Polish Mother’s Memorial Hospital–Research Institute, Lodz, Poland
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values (insulin plus glucose/triglycerides) with indices of IR derived from glucose and insulin measurements during 75 g oral glucose tolerance test (OGTT), such as Insulin Resistance (Belfiore) Index (IRI) ( 9 ), Matsuda index ( 10 ) and Stumvoll index
Institute of Clinical Research, University of Southern Denmark, Odense, Denmark
Department of Endocrinology, Hospital of Southwest Jutland, Esbjerg, Denmark
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finding in most of the previous studies of the glucose metabolism. Suzuki et al . ( 17 ) studied 10 non-DM and 14 DM m.3243A>G carriers and found a markedly reduced glucose-stimulated insulin secretion during an OGTT and lower 24-h urine c-peptide levels