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Dipartimento di Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno-infantili, Università di Genova, Genova, Italy
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Dipartimento di Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno-infantili, Università di Genova, Genova, Italy
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have also shown that the best GH peak cut-off ranges from 5.1 to 6.8 μg/L, depending on the stimulation test ( 13 ). Measurement of IGF1 is also an important step in the diagnostic process ( 10 , 14 ). IGF1 is a small polypeptide hormone, whose
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-2000i, Shenzhen, China), with intra- and inter-assay CVs of LH, FSH, and E2 less than 10%. Insulin-like growth factor-1 (IGF-1) was tested by chemiluminescence (BIOBASE, MAGLUMI 4000 plus, Shandong, China). The serum MKRN3 and kisspeptin levels were
Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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.0%). Recovery of GH/IGF-I axis was confirmed in 28.2% of all patients in this cohort (40/142). The prevalence of GH/IGF-I axis recovery was greatest in the IDOP subgroup (31/43; 72%). TUMC and CONG groups demonstrated a significantly lower prevalence of
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( 14 ). It is well known that GH and insulin-like growth factor (IGF-I) have also an impact on bone age ( 4 , 26 , 27 ). Therefore, deficiencies in GH and IGF-I lead to growth impairment and bone age delay, while overproduction or administration of GH
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-Nardi J . The roles of insulin sensitivity, insulin-like growth factor I (IGF-I), and IGF-binding protein-1 and -3 in the hyperandrogenism of African-American and Caribbean Hispanic girls with premature adrenarche . Journal of Clinical Endocrinology and
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Section of Biostatistics, Department of Public Health, University of Copenhagen, Copenhagen, Denmark
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– 186 . ( https://doi.org/10.1016/j.cca.2017.03.002 ) 14 Mieritz MG Rakêt LL Hagen CP Nielsen JE Talman MLM Petersen JH Sommer SH Main KM Jørgensen N Juul A . A longitudinal study of growth, sex steroids, and IGF-1 in boys with
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Department of Pediatrics, China-Japan Friendship Hospital, Beijing, China
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. Growth Hormone and IGF Research 2018 38 29 – 33 . ( https://doi.org/10.1016/j.ghir.2017.12.003 ) 26 Silventoinen K Determinants of variation in adult body height . Journal of Biosocial Science 2003 35 263 – 285 . ( https://doi.org/10