EndoERN, APHP Consortium Pitie Salpetriere Hospital, Necker Hospital, Paris, France
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EndoERN, APHP Consortium Pitie Salpetriere Hospital, Necker Hospital, Paris, France
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EndoERN, APHP Consortium Pitie Salpetriere Hospital, Necker Hospital, Paris, France
Sorbonne University, Paris, France
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Introduction Growth hormone (GH) is a pituitary hormone with pleiotropic effects. After being secreted into the general circulation, GH binds to its receptor with subsequent direct effects and insulin-like growth factor (IGF)-mediated effects
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, insulin-like growth factor-1 (IGF-1), insulin) have shown potential roles in the diagnosis of CPP ( 10 , 11 , 12 ). Recently, Kutlu et al. ( 13 ) reported the role of another novel adipomyokine, irisin, in the diagnosis of CPP, and their study implied
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childhood, followed by a sharp acceleration from the onset of puberty onward, up to early adulthood. During puberty, the growth hormone (GH)/insulin-like growth factor (IGF)-1 axis and sex steroids become the main determinants of bone development, acting on
Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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Endocrinology and Metabolism 1998 271 – 276 . ( https://doi.org/10.1016/s1043-2760(9800069-132 ) 32 Aksglaede L Skakkebaek NE & Juul A . Abnormal sex chromosome constitution and longitudinal growth: serum levels of insulin-like growth factor (IGF
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Department of Medicine, University of Padova, Padova, Italy
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F Sinnesael M Gielen E Boonen S & Vanderschueren D . Skeletal sexual dimorphism: relative contribution of sex steroids, GH–IGF1, and mechanical loading . Journal of Endocrinology 2010 207 127 – 134 . ( https://doi.org/10.1677/JOE-10
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Section of Biostatistics, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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. Archives of Disease in Childhood 1999 81 10 – 15 . ( https://doi.org/10.1136/adc.81.1.10 ) 45 Aksglaede L Skakkebaek NE & Juul A . Abnormal sex chromosome constitution and longitudinal growth: serum levels of insulin-like growth factor (IGF
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2019 186 79 – 88 . ( https://doi.org/10.1016/j.jsbmb.2018.09.019 ) 14 Halhali A Diaz L Barrera D Avila E & Larrea F . Placental calcitriol synthesis and IGF-I levels in normal and preeclamptic pregnancies . Journal of Steroid