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A1; SRB1, scavenger receptor b1; FGF19/21, fibroblast growth factors 19/21; HMG-COA, 3-hydroxy-3-methyl glutaryl coenzyme A; ACC, acetyl-CoA carboxylase; FAS, fatty acid synthase; CPT1A, carnitine palmitoyltransferase Iα; WAT, white adipose tissue