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Department of Endocrinology, Trondheim University Hospital (St Olavs Hospital), Trondheim, Norway
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Medical Clinic, Trondheim University Hospital (St Olavs Hospital), Trondheim, Norway
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Department of Gastroenterology, Trondheim University Hospital (St Olavs Hospital), Trondheim, Norway
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K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Trondheim, Norway
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Medical Clinic, Trondheim University Hospital (St Olavs Hospital), Trondheim, Norway
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osteoporosis and fractures and secondary osteoporosis due to various underlying systemic disorders ( 9 ). Accumulation of advanced glycation end products (AGEs) has been proposed to affect bone quality in subjects with diabetes ( 3 , 10 ). Pentosidine is a
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expressed in all human tissues. In addition to regulating adenosine concentration by catalyzing the irreversible deamination of adenosine to inosine ( 5 ), ADA is also essential for the differentiation and maturation of T lymphocytes and is a general marker
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, serum creatinine (SCr), serum calcium, serum inorganic phosphate, urinary calcium and PTH, as well as bone turnover markers (BTMs), including bone-specific alkaline phosphatase (bALP), N-terminal propeptide of type 1 collagen (P1NP), type I collagen
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tumour removal ( 53 ), therefore systemic inflammation may also influence our results. We are aware of the limitations of our study. PHEO is a rare disease, and we are not able to enroll a larger number of patients into the study. Moreover, speckle
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AITDs and disease progression ( 7 , 8 ). AITDs mainly have two types of symptoms, Graves’ disease (GD) and Hashimoto’s thyroiditis (HT). HT is the most common thyroid inflammation characterized by abnormally elevated thyroglobulin antibodies (TGAb) and
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levels of TNF-α in the serum of GD patients may be affect to a systemic response to disease or to an intrathyroidal antigen–antibody reciprocity. Increase of cytokines in the thyroid gland may lead to the production of other cytokines by autoreactive
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inhibit the systemic inflammatory response and regulate the function of pancreatic islets based on this pancreas–inflammation–intestine regulatory axis, which once again clarifies the inseparable relationship between the pancreas, inflammation, and
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guidelines ( 11 ). In fact, there is currently no adjuvant systemic treatment that can eliminate residual disease and R0 resection is pivotal. For inoperable cases or frequent structural recurrence after repetitive surgery, external beam radiation (EBRT) is
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Department of Pharmacology, Department of Biology, Toxicology and Therapeutics, School of Medicine, University of Kansas Medical Center, Room 4061 of KLSIC Building, 2146 West 39th Street, Kansas City, Kansas 66160, USA
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) Histological changes in H/E-stained tissue sections. (E) The severity of skin inflammation on the back of mice at 8 days after first sensitization with DNCB. It should be noted that in the data shown in this figure, mice labeled as group ‘E 3 ’ received E 3
Department of Research and Development, Region Kronoberg, Växjö, Sweden
Region Kronoberg, Primary Care, Växjö, Sweden
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Department of Research and Development, Region Kronoberg, Växjö, Sweden
Department of Internal Medicine, Endocrinology and Diabetes, Central Hospital, Växjö, Sweden
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activation of the innate immune system causing systemic inflammation ( 2 , 3 , 5 , 6 , 7 ). We have previously shown in these patients with T1D that depression was associated with inadequate glycaemic control ( 8 ), and with high midnight salivary