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–8% (49) (with anti-PD-1) Seen less commonly in anti-CTLA-4 therapy (8, 9) Anti-thyroid drugs only in Graves’ disease (51, 52, 53, 54, 55) 14–20% (combined therapy) (49, 50) High dose steroids if severe thyroiditis seen (49
Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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that their kit is up to date Provide the patient with a Steroid Emergency Card www.endocrinology.org/adrenal-crisis and encourage them to wear medical alert bracelets, in addition to keeping the steroid emergency card with them at all times and
Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA
Veterans Affairs Medical Center, Ann Arbor, Michigan, USA
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-0540 ) 4 Baggish AL Weiner RB Kanayama G Hudson JI Lu MT Hoffmann U Pope Jr HG . Cardiovascular toxicity of illicit anabolic-androgenic steroid use . Circulation 2017 135 1991 – 2002 . ( https://doi.org/10.1161/CIRCULATIONAHA.116
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Department of Physiology, Faculty of Science, Charles University, Prague, Czech Republic
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Department of Physiology, Faculty of Science, Charles University, Prague, Czech Republic
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biologically inactive 11-oxo steroids (cortisone and 11-dehydrocorticosterone) to cortisol and corticosterone, amplifying the cellular glucocorticoid action ( 5 ). 11HSD1 is expressed in many organs and tissues, including lymphoid organs and immune cells ( 6
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CUNY Graduate School of Public Health and Health Policy, New York, New York, USA
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Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA
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Introduction Estradiol (17β-estradiol) is a natural sex steroid available in several exogenous preparations. The Endocrine Society recommended high-dose exogenous estradiol treatment as one part of feminizing hormone therapy for transgender
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Serviço de Endocrinologia, Departamento de Endocrinologia, Faculdade de Medicina da Universidade do Porto, Al. Prof. Hernâni Monteiro, 4200-319 Porto, Portugal
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) and ethinyl oestradiol (EE) (20) , as well as non-steroidal anti-inflammatory drugs (NSAID) and acetaminophen (21) . Natural chemicals such as genistein, a phytoestrogen (22) and heavy metals (23) can also have endocrine-disruptive effects
Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
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continuous infusion of the labeled steroid in a dialysate matrix. The abundance was compared between a dialysate matrix and mobile phase at the retention time of testosterone. Total imprecision was assessed by an adapted CLSI EP5 protocol with pooled
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, more evidence demonstrates estrogen could influence cell proliferation and migration elicited by combining steroid hormone receptors such as G protein-coupled estrogen receptor 1 (GPER), ERβ or estrogen-related receptors ( 7 , 8 , 9 , 10 ). GPER
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Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Diamant M. Steroid diabetes: from mechanism to treatment? Netherlands Journal of Medicine 2014 72 62 – 72 . 2 Ellis ME Weiss RB Korzun AH Rice MA Norton L Perloff M Lesnick GJ Wood WC . Hyperglycemic complications associated
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tissues, particularly on adipose tissue. The sexual dimorphism of androgens in the pathophysiology of T2DM is emphasized. Sex hormone differences between the sexes Males and females produce the same steroid hormones in a similar way. Regarding
