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Wei Sun Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning Province, China

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Boyuan Zheng Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning Province, China

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Zhihong Wang Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning Province, China

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Wenwu Dong Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning Province, China

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Yuan Qin Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning Province, China

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Hao Zhang Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning Province, China

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and Zheng BY) independently completed the selection process. Differences were resolved via discussion Selection criteria The meta-analysis included studies that met these criteria: (a) Retrospective or prospective cohort studies; (b) the lesion

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Nadine M Vaninetti Division of Endocrinology and Metabolism, Dalhousie University, Halifax, Nova Scotia, Canada

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David B Clarke Division of Neurosurgery, Dalhousie University, Halifax, Nova Scotia, Canada

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Deborah A Zwicker Cape Breton Regional Hospital, Sydney, Nova Scotia, Canada

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Churn-Ern Yip Division of Endocrinology and Metabolism, Dalhousie University, Halifax, Nova Scotia, Canada

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Barna Tugwell Division of Endocrinology and Metabolism, Dalhousie University, Halifax, Nova Scotia, Canada

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Steve Doucette Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada

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Chris Theriault Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada

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Khaled Aldahmani Department of Medicine, Tawam Hospital in Affiliation with Johns Hopkins, AI Ain, UAE

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Syed Ali Imran Division of Endocrinology and Metabolism, Dalhousie University, Halifax, Nova Scotia, Canada

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standardized criteria by a single team comprising an endocrinologist and neurosurgeon as well as specialized nurses from endocrinology and neurosurgery. Study design A retrospective analysis was carried out on all patients within HNP database meeting

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Dorte Glintborg Department of Endocrinology, Odense University Hospital, Odense, Denmark
Institute of Clinical Research, University of Southern Denmark, Odense, Denmark

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Katrine Hass Rubin Open Patient Data Explorative Network, Department of Clinical Research, University of Southern Denmark and Odense University Hospital, Odense, Denmark

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Simon Bang Mohr Kristensen Open Patient Data Explorative Network, Department of Clinical Research, University of Southern Denmark and Odense University Hospital, Odense, Denmark

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Øjvind Lidegaard Department of Gynecology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark

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Guy T’Sjoen Department of Endocrinology and Center for Sexology and Gender, Ghent University Hospital, Gent, Belgium

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Aisa Burgwal Department of Endocrinology and Center for Sexology and Gender, Ghent University Hospital, Gent, Belgium

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Malene Hilden Department of Gynecology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Centre for Gender Identity, Department of Gynaecology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Marianne Skovsager Andersen Department of Endocrinology, Odense University Hospital, Odense, Denmark
Institute of Clinical Research, University of Southern Denmark, Odense, Denmark

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with general wellbeing ( 10 ). Previous studies regarding SES in transgender cohorts examined selected sub-cohorts of transgender populations ( 10 , 11 , 13 ). One previous national study in Belgium showed that a high proportion of transgender persons

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Yang Lv Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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Ning Pu Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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Wei-lin Mao Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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Wen-qi Chen Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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Huan-yu Wang Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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Xu Han Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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Yuan Ji Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai, China

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Lei Zhang Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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Da-yong Jin Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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Wen-Hui Lou Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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Xue-feng Xu Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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Supplementary data (see section on supplementary data given at the end of this article). Results Comparison of the clinical characteristics of rectal NECs between SEER cohort and our center In this study, the clinical data of 41 patients and 1355

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Timothy J Morris Directorate of Biochemistry, Manchester University NHS Foundation Trust, Manchester, UK
Faculty of Biology Medicine and Health, University of Manchester, Manchester, UK

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Andrew Whatmore Division of Developmental Biology and Medicine, University of Manchester, Royal Manchester Children’s Hospital, Manchester, UK

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Laura Hamilton Pathology Department, Clinical Biochemistry, Huddersfield Royal Infirmary, Lindley, Huddersfield, UK

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Beverly Hird Directorate of Biochemistry, Manchester University NHS Foundation Trust, Manchester, UK

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Eric S Kilpatrick Directorate of Biochemistry, Manchester University NHS Foundation Trust, Manchester, UK

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Lesley Tetlow Directorate of Biochemistry, Manchester University NHS Foundation Trust, Manchester, UK

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Peter Clayton Division of Developmental Biology and Medicine, University of Manchester, Royal Manchester Children’s Hospital, Manchester, UK

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were obtained retrospectively from the laboratory computer system (APEX). The assay methodology was changed from PRA to PRC in May 2015. Two cohorts were established: one comprised the last 50 PRA measurements made before the switch and the other

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Agnieszka Adamska Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Bialystok, Poland

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Vitalii Ulychnyi Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Bialystok, Poland

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Katarzyna Siewko Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Bialystok, Poland

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Anna Popławska-Kita Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Bialystok, Poland

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Małgorzata Szelachowska Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Bialystok, Poland

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Marcin Adamski Faculty of Computer Science, Bialystok University of Technology, Białystok, Poland

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Angelika Buczyńska Clinical Research Centre, Medical University of Bialystok, Bialystok, Poland

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Adam Jacek Krętowski Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Bialystok, Poland
Clinical Research Centre, Medical University of Bialystok, Bialystok, Poland

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. Materials and methods Subjects In this study, we retrospectively analysed the records of 335 patients with adrenal incidentaloma referred to the Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, between

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Daniel Bell Department of Pharmacy, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK

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Julia Hale Department of Endocrinology, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK

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Cara Go Department of Endocrinology, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK

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Ben G Challis Department of Endocrinology, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK

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Tilak Das Department of Radiology, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK

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Brian Fish Department of Head and Neck Surgery, Cambridge University NHS Foundation Trust, Cambridge, UK

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Ruth T Casey Department of Endocrinology, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK
Department of Medical Genetics, Cambridge University, Cambridge, UK

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with a higher final dose of cinacalcet, in line with our study findings. Thresholds for initiation at a higher dose of cinacalcet were not discussed in the literature. Discussion We have retrospectively analysed a large cohort of patients who

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Marie Lindhardt Ljubicic Department of Growth and Reproduction, Copenhagen University Hospital – Rigshospitalet, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Trine Holm Johannsen Department of Growth and Reproduction, Copenhagen University Hospital – Rigshospitalet, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Margit Bistrup Fischer Department of Growth and Reproduction, Copenhagen University Hospital – Rigshospitalet, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Emmie N Upners Department of Growth and Reproduction, Copenhagen University Hospital – Rigshospitalet, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Alexander S Busch Department of Growth and Reproduction, Copenhagen University Hospital – Rigshospitalet, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Katharina M Main Department of Growth and Reproduction, Copenhagen University Hospital – Rigshospitalet, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark

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Anna-Maria Andersson Department of Growth and Reproduction, Copenhagen University Hospital – Rigshospitalet, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Casper P Hagen Department of Growth and Reproduction, Copenhagen University Hospital – Rigshospitalet, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Anders Juul Department of Growth and Reproduction, Copenhagen University Hospital – Rigshospitalet, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark

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in girls, at 1 year of age ( 9 , 10 ). Thus, the LH/FSH ratio in a larger cohort of patients with DSD during the entire first year of life remains to be examined. The aim of this study was therefore to explore and describe the LH/FSH ratio in

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Sarah Byberg Department of Medical Endocrinology, Copenhagen University Hospital, Copenhagen, Denmark

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Jesper Futtrup Panum Institute, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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Mikkel Andreassen Department of Medical Endocrinology, Copenhagen University Hospital, Copenhagen, Denmark

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Jesper Krogh Department of Medical Endocrinology, Copenhagen University Hospital, Copenhagen, Denmark

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Introduction In recent large cohort studies, high prolactin levels within and above the normal physiological range have been associated with increased risk of cardiovascular mortality ( 1 , 2 , 3 ). It is speculated whether this association

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Elena Izkhakov Institute of Endocrinology, Metabolism and Hypertension, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
School of Public Health, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel

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Joseph Meyerovitch Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Community Division, Clalit Health Services, Tel Aviv, Israel
The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children’s Medical Center of Israel, Petah Tikva, Israel

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Micha Barchana School of Public Health, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel

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Yacov Shacham Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Department of Cardiology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

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Naftali Stern Institute of Endocrinology, Metabolism and Hypertension, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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Lital Keinan-Boker School of Public Health, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel
National Cancer Registry, Israel Center for Disease Control, Ministry of Health, Israel, Ramat Gan, Israel

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retrospective cohort study did reveal increased cerebrovascular events in both hyperthyroid and euthyroid patients treated with radioiodine for benign thyroid disorders ( 21 ). This supports the possible contribution of radioiodine treatment to cerebrovascular

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