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mucosa ( 40 ). Pseudohypoparathyroidism In pseudohypoparathyroidism (PHP), symptoms of parathyroid hypofunction (hypoparathyroidism) appear without a deficiency of parathyroid hormone (PTH) in the blood. The parathormone effect is absent due to
Department of Nutrition, Institute of Life Sciences, Federal University of Juiz de Fora, Governador Valadares, Minas Gerais, Brazil
Department of Nutrition, Faculty of Health and Medical Sciences, University of Surrey, University of Surrey, Guildford, UK
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for bone health in adults include the suppression of parathyroid hormone secretion, higher bone mineral density, reduced rates of bone loss, and decreases in fractures and falls ( 10 , 54 ). There is a general comprehension that circulating 25(OH
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nutrient with a threshold and influence on bone turnover under conditions of vitamin D insufficiency. The mechanism of the association may be that the parathyroid hormone (PTH) mediates vitamin D and bone turnover. A continuous elevation in serum PTH with
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period, with or without biochemical marker improvement (alkaline phosphatase, serum parathyroid hormone, calcium, phosphate). Regarding ethical considerations, this study was approved by the institutional review board Research Advisory Council at King
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Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands
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. Osteoporosis International 1999 9 351 – 35 7 . ( https://doi.org/10.1007/s001980050158 ) 16 Roof BS Piel CF Hansen J Fudenberg HH Serum parathyroid hormone levels and serum calcium levels from birth to senescence . Mechanisms of Ageing and
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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of OP is influenced by many factors, such as sex hormone deficiency, calcium and vitamin D deficiency, elevated parathyroid hormone (PTH) levels, disturbance of inflammatory cytokines induced by inflammatory diseases, etc., resulting in decreased
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Faculty of Life Sciences and Medicine, Kings College London, London, UK
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Department of Clinical Biochemistry, King’s College Hospital NHS Foundation Trust, Denmark Hill, London, UK
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Neuroendocrine Tumour Unit, Kings Health Partners ENETS Centre of Excellence, Denmark Hill, London, UK
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Barts and the London School of Medicine, Centre for Endocrinology, William Harvey Institute, London, UK
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Faculty of Life Sciences and Medicine, Kings College London, London, UK
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Faculty of Life Sciences and Medicine, School of Life Course Sciences, Obesity Immunometabolism and Diabetes Group, King’s College London, London, UK
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, amines or cytokines isec more commonly seen by neoplasms that are formed in the gut ( 2 , 4 , 5 ). Endocrine PNS is the term used when PNS is from the ectopic secretion of a hormone, and can lead to diagnostic uncertainty, as it can manifest with
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Department of Emergency Medicine, CHU Nantes, Nantes, France
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. All other biochemical parameters such as total 25 OH vitamin D on LIAISONXL (DiaSorin), total protein and magnesium on Cobasc701(Roche Diagnostics) and intact parathyroid hormone (PTH) on Cobase602 (Roche Diagnostics) were measured according to the
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. Competency 4 : Endocrine dynamic function testing. Competency 5 : Growth hormone deficiency. Competency 6 : Hypo- and hyperparathyroidism. Competency 7 : Hypogonadism. Competency 8 : Hypopituitarism. Competency 9 : Osteoporosis. Competency 10 : Polycystic
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Réseau TenGen, Marseille, France
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Fédération d’Endocrinologie, Hospices Civils de Lyon, Université Lyon 1, France
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Service de Génétique, AP-HP, Hôpital européen Georges Pompidou, Paris, France
Université de Paris, PARCC, INSERM, Paris, France
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Department of Endocrinology, Assistance Publique-Hôpitaux de Marseille (AP-HM), Hôpital de la Conception, Centre de Référence des Maladies Rares de l’hypophyse HYPO, Marseille, France
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Aix Marseille Univ, APHM, INSERM, MMG, Laboratory of Molecular Biology, Hospital La Conception, Marseille, France
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Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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endocrine work-up and was judged by the MEN 2 experts participating in the study. PHPT had to be both biochemically (hypercalcemia and an elevated or inappropriately normal parathyroid hormone level ( 30 )) and histologically proven, while MTC