Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Garvan Institute of Medical Research, New South Wales, Australia
School of Medical Sciences, University of New South Wales, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Department of Diabetes and Endocrinology, Westmead Hospital, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
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Faculty of Medicine, Health and Human Sciences, Macquarie University, New South Wales, Australia
Crown Princess Mary Cancer Centre, Westmead Hospital, New South Wales, Australia
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Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
Steno Diabetes Center Odense, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
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Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
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this study of metformin treatment was to assess a change in the IGF/IGFBP system: IGF-1 and -2, IGF bioactivity, IGFBP-1 to -3, and IGFBP activity modulators PAPP-A and STC2. Glucose and insulin indices Glucose metabolism was assessed using the
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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with T2DM suffer from obesity ( 3 , 4 ). Overloaded energy intake and physical inactivity result in obesity characterized by rapid expansion of adipose tissue. As obesity progresses, adipose expansion outpaces the growth of vasculature, leading to
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.3 ( 2 ), which is consistent with the susceptible sites for metabolic syndrome (MS). It has a wide range of physiological functions such as regulating blood glucose and lipid metabolism and inhibiting tissue calcification ( 3 , 4 , 5 ). Previous
Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Ministry of Education of the People’s Republic of China, Hefei, Anhui, China
NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, Anhui, China
Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, Anhui, China
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Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Ministry of Education of the People’s Republic of China, Hefei, Anhui, China
NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, Anhui, China
Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, Anhui, China
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Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Ministry of Education of the People’s Republic of China, Hefei, Anhui, China
NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, Anhui, China
Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, Anhui, China
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Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Ministry of Education of the People’s Republic of China, Hefei, Anhui, China
NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, Anhui, China
Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, Anhui, China
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Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Ministry of Education of the People’s Republic of China, Hefei, Anhui, China
NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, Anhui, China
Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, Anhui, China
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Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Ministry of Education of the People’s Republic of China, Hefei, Anhui, China
NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, Anhui, China
Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, Anhui, China
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Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Ministry of Education of the People’s Republic of China, Hefei, Anhui, China
NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, Anhui, China
Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, Anhui, China
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glucose abnormality ( 11 ). In addition, T3 can exert an important effect on the control of energy expenditure. For instance, under the effect of T3, skeletal muscle energy metabolism is switched into oxidative mitochondrial metabolism mediated by PGC-1α
Université Côte d'Azur, INSERM, C3M, Team Cellular and Molecular Physiopathology of Obesity and Diabetes, Nice, France
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is to regulate energy homeostasis through the regulation of cellular metabolism. This adipokine has important additional effects, as in fact it is able to trigger a series of downstream signaling pathways, including both canonical (JAK2/STATs, MAPK
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little is known about lipoprotein and glucose metabolism in middle-aged and older woman with a prior history of GDM. We hypothesized that pre- and postmenopausal women who have a history of GDM would be more obese with lower aerobic fitness, have greater
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and prevent the development of chronic complications. Excessive energy intake is one of the contributing factors that play a part in the observed weight gain in patients with type 2 diabetes mellitus ( 2 ). In addition, many antidiabetic agents
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have received extensive attention and been widely researched, but few studies have focused on adipo-IR. Thyroid hormones play a core part in energy metabolism and body weight balance ( 7 ). Mild deviation of thyroid function within the reference range
Developmental Endocrinology Research Group, University of Glasgow, Glasgow, UK
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Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK
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Centre for Endocrinology, William Harvey Research Institute, Barts and The London Medical School, Queen Mary University of London, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, Hammersmith Hospital, London, UK
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Department of Paediatric Endocrinology, Makarios Children's Hospital, Nicosia, Cyprus
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Sussex Community NHS Trust, Brighton, UK
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Developmental Endocrinology Research Group, University of Glasgow, Glasgow, UK
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The University of Dublin, Trinity College Dublin, Dublin, Republic of Ireland
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.2147/AHMT.S214893 ) 31 Alsaif M Elliot SA MacKenzie ML Prado CM Field CJ & Haqq AM . Energy Metabolism profile in individuals with Prader-Willi syndrome and implications for clinical management: a systematic review . Advances in Nutrition
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and of energy disposal ( 38 ). To further support this association, studies conducted in patients with prostate cancer undergoing androgen deprivation therapy (ADT) have shown that lack of testosterone production is responsible for metabolic effects