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Ruth Therese Casey Department of Endocrinology, University of Cambridge, Cambridge Biomedical Research Centre, Addenbrooke’s Hospital, Cambridge, UK

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Deborah Saunders East Anglian Regional Radiation Protection Service, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK

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Benjamin George Challis Department of Endocrinology, University of Cambridge, Cambridge Biomedical Research Centre, Addenbrooke’s Hospital, Cambridge, UK

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Deborah Pitfield Department of Endocrinology, University of Cambridge, Cambridge Biomedical Research Centre, Addenbrooke’s Hospital, Cambridge, UK

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Heok Cheow Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK

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Ashley Shaw Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK

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Helen Lisa Simpson Wolfson Diabetes and Endocrine Clinic, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK

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-mediated RNA decay of the translated protein ( 20 ). It is notable that two patients were found to have breast cancer, which may be a MEN1-related tumour ( 21 ), but no other solid tumours or haematological malignancies not normally associated with MEN1 were

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Jing Wang Tianjin Women’s and Children’s Health Center Tianjin, China
Chronic Disease Epidemiology Laboratory Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA

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Leishen Wang Tianjin Women’s and Children’s Health Center Tianjin, China

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Huikun Liu Tianjin Women’s and Children’s Health Center Tianjin, China

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Shuang Zhang Tianjin Women’s and Children’s Health Center Tianjin, China

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Junhong Leng Tianjin Women’s and Children’s Health Center Tianjin, China

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Weiqin Li Tianjin Women’s and Children’s Health Center Tianjin, China

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Tao Zhang Tianjin Women’s and Children’s Health Center Tianjin, China

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Nan Li Tianjin Women’s and Children’s Health Center Tianjin, China

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Wei Li Tianjin Women’s and Children’s Health Center Tianjin, China

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Andrea A Baccarelli Department of Environmental Health Sciences Columbia University Mailman School of Public Health, New York, New York, USA

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Lifang Hou Department of Preventive Medicine Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA

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Gang Hu Chronic Disease Epidemiology Laboratory Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA

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as gender, birth date, age, birth weight, birth length, the mode of infant feeding within the first 6 months (exclusive formula, mixed breast and formula or exclusive breast) and lactation duration; history of diseases and medication; dietary habits

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Jiali Tian Ultrasound Department, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China

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Jinlei Liang Ultrasound Department, Zhuhai People's Hospital, Zhuhai, China

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Yuhong Lin Ultrasound Department, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China

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Liping Wang Ultrasound Department, Zhuhai Xiangzhou District People's Hospital, Zhuhai, China

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Xiaobo Chen Ultrasound Department, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, China

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differentiation of benign and malignant breast lesions ( 19 ). Nevertheless, the role of SMI in distinguishing MTNs and PTCs remains unknown. This study aimed to compare the SMI blood-flow features of MTNs and PTCs and to explore the diagnostic value of ACR

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Sofia S Pereira Department of Anatomy and UMIB (Unit for Multidisciplinary Biomedical Research) of ICBAS, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Department of Endocrinology, University of Porto, Porto, 4050-313, Portugal
Department of Anatomy and UMIB (Unit for Multidisciplinary Biomedical Research) of ICBAS, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Department of Endocrinology, University of Porto, Porto, 4050-313, Portugal

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Tiago Morais Department of Anatomy and UMIB (Unit for Multidisciplinary Biomedical Research) of ICBAS, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Department of Endocrinology, University of Porto, Porto, 4050-313, Portugal

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Madalena M Costa Department of Anatomy and UMIB (Unit for Multidisciplinary Biomedical Research) of ICBAS, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Department of Endocrinology, University of Porto, Porto, 4050-313, Portugal

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Mariana P Monteiro Department of Anatomy and UMIB (Unit for Multidisciplinary Biomedical Research) of ICBAS, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Department of Endocrinology, University of Porto, Porto, 4050-313, Portugal

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Duarte Pignatelli Department of Anatomy and UMIB (Unit for Multidisciplinary Biomedical Research) of ICBAS, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Department of Endocrinology, University of Porto, Porto, 4050-313, Portugal
Department of Anatomy and UMIB (Unit for Multidisciplinary Biomedical Research) of ICBAS, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Department of Endocrinology, University of Porto, Porto, 4050-313, Portugal

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; colon carcinoma for p53 and Ki-67; breast cancer for IGF1R, MDM2, cyclin D1, and β-catenin; tonsil for p21 and p27, and lung adenocarcinoma for E-cadherin. Computerized image analysis Using the camera AxioCam MRC Zeiss, ten photos were taken for each

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Norra Kwong Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA

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Ellen Marqusee Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA

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Michael S Gordon Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA
Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA

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P Reed Larsen Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA

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Jeffrey R Garber Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA
Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA

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Matthew I Kim Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA

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Erik K Alexander Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA

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variable concentrations ( 131 I therapy) 5 43-year-old female Lungs 203 mCi (age 77) 85 years old (local LN removal) >13 years b + PET activity (lungs) Died of metastatic breast cancer at the age of 90 years old. Stable

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Lei Hu Department of Ultrasound, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China

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Xiao Liu Department of Ultrasound, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China

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Chong Pei Department of Respiratory and Critical Care Medicine, The First People’s Hospital of Hefei City, The Third Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China

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Li Xie Department of Ultrasound, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China

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Nianan He Department of Ultrasound, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China

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differentiation of benign and malignant TNs and breast lesions ( 20 , 21 , 22 , 23 , 24 , 25 ). In particular, the 2 mm-perinodular stiffness of TNs measured by the Shell measurement function may be an accurate diagnostic index for differentiating malignant

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Sneha Arya Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

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Sandeep Kumar Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

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Anurag R Lila Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

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Vijaya Sarathi Department of Endocrinology, Vydehi Institute of Medical Sciences and Research Centre, Bangalore, India

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Saba Samad Memon Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

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Rohit Barnabas Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

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Hemangini Thakkar Department of Radiology, Seth G S Medical College & KEM Hospital, Mumbai, India

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Virendra A Patil Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

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Nalini S Shah Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

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Tushar R Bandgar Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

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-onset nephropathy, and gonadoblastoma). His younger sister (P4b) was 46,XY DSD, presented with primary amenorrhea at 17 years of age and had female external genitalia with normal breast development on examination. At presentation, her gonads were non-localizable on

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Xingyan Liu Department of Obstetrics & Gynecology, General Hospital of PLA Eastern Theater (Nanjing General Hospital of Nanjing Military Command), Command, Nanjing, China

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Mei Xu Department of Obstetrics & Gynecology, General Hospital of PLA Eastern Theater (Nanjing General Hospital of Nanjing Military Command), Command, Nanjing, China

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Min Qian Department of Obstetrics & Gynecology, General Hospital of PLA Eastern Theater (Nanjing General Hospital of Nanjing Military Command), Command, Nanjing, China

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Lindong Yang Department of Obstetrics & Gynecology, General Hospital of PLA Eastern Theater (Nanjing General Hospital of Nanjing Military Command), Command, Nanjing, China

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). Polymorphisms of CYP17 T/C gene have been proved to result in increased synthesis of androgen and a higher risk of the development of several diseases, such as breast cancer ( 20 ), prostate cancer ( 21 ) and endometriosis ( 22 ) et al. , which was genotyped in

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Willem de Ronde Department of Internal Medicine, Spaarne Gasthuis, Haarlem, the Netherlands

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Diederik L Smit Department of Internal Medicine, Spaarne Gasthuis, Haarlem, the Netherlands

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the 5α-reductase enzymes. Administration of supraphysiological doses of testosterone thus results in increased levels of oestradiol and DHT. Elevated oestradiol levels are responsible for a number of side effects: they may stimulate breast glandular

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Thomas Crezee Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands
Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands

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Mirela Petrulea Department of Endocrinology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania

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Doina Piciu Department of Endocrinology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands

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Martin Jaeger Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands
Department of Nuclear Medicine and Endocrine Tumors, Institute of Oncology ‘Prof. Dr. Ion Chiricuta’, Cluj-Napoca, Romania

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Jan W A Smit Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands

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Theo S Plantinga Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands
Department of Nuclear Medicine and Endocrine Tumors, Institute of Oncology ‘Prof. Dr. Ion Chiricuta’, Cluj-Napoca, Romania

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Carmen E Georgescu Department of Endocrinology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
Endocrinology Clinic, Cluj County Emergency Hospital, Cluj-Napoca, Romania

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Romana Netea-Maier Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands
Department of Nuclear Medicine and Endocrine Tumors, Institute of Oncology ‘Prof. Dr. Ion Chiricuta’, Cluj-Napoca, Romania

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-AKT-mTOR pathway, obesity, and breast cancer disease-free survival . Breast Cancer Research and Treatment 2014 147 381 – 387 . ( https://doi.org/10.1007/s10549-014-3081-9 ) 25108739 31 Pfisterer K Fusi A Klinghammer K Knodler M Nonnenmacher A

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