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-mediated RNA decay of the translated protein ( 20 ). It is notable that two patients were found to have breast cancer, which may be a MEN1-related tumour ( 21 ), but no other solid tumours or haematological malignancies not normally associated with MEN1 were
Chronic Disease Epidemiology Laboratory Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA
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as gender, birth date, age, birth weight, birth length, the mode of infant feeding within the first 6 months (exclusive formula, mixed breast and formula or exclusive breast) and lactation duration; history of diseases and medication; dietary habits
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differentiation of benign and malignant breast lesions ( 19 ). Nevertheless, the role of SMI in distinguishing MTNs and PTCs remains unknown. This study aimed to compare the SMI blood-flow features of MTNs and PTCs and to explore the diagnostic value of ACR
Department of Anatomy and UMIB (Unit for Multidisciplinary Biomedical Research) of ICBAS, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Department of Endocrinology, University of Porto, Porto, 4050-313, Portugal
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Department of Anatomy and UMIB (Unit for Multidisciplinary Biomedical Research) of ICBAS, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Department of Endocrinology, University of Porto, Porto, 4050-313, Portugal
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; colon carcinoma for p53 and Ki-67; breast cancer for IGF1R, MDM2, cyclin D1, and β-catenin; tonsil for p21 and p27, and lung adenocarcinoma for E-cadherin. Computerized image analysis Using the camera AxioCam MRC Zeiss, ten photos were taken for each
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Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA
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Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA
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variable concentrations ( 131 I therapy) 5 43-year-old female Lungs 203 mCi (age 77) 85 years old (local LN removal) >13 years b + PET activity (lungs) Died of metastatic breast cancer at the age of 90 years old. Stable
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differentiation of benign and malignant TNs and breast lesions ( 20 , 21 , 22 , 23 , 24 , 25 ). In particular, the 2 mm-perinodular stiffness of TNs measured by the Shell measurement function may be an accurate diagnostic index for differentiating malignant
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-onset nephropathy, and gonadoblastoma). His younger sister (P4b) was 46,XY DSD, presented with primary amenorrhea at 17 years of age and had female external genitalia with normal breast development on examination. At presentation, her gonads were non-localizable on
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). Polymorphisms of CYP17 T/C gene have been proved to result in increased synthesis of androgen and a higher risk of the development of several diseases, such as breast cancer ( 20 ), prostate cancer ( 21 ) and endometriosis ( 22 ) et al. , which was genotyped in
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the 5α-reductase enzymes. Administration of supraphysiological doses of testosterone thus results in increased levels of oestradiol and DHT. Elevated oestradiol levels are responsible for a number of side effects: they may stimulate breast glandular
Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands
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Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
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Department of Nuclear Medicine and Endocrine Tumors, Institute of Oncology ‘Prof. Dr. Ion Chiricuta’, Cluj-Napoca, Romania
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Endocrinology Clinic, Cluj County Emergency Hospital, Cluj-Napoca, Romania
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-AKT-mTOR pathway, obesity, and breast cancer disease-free survival . Breast Cancer Research and Treatment 2014 147 381 – 387 . ( https://doi.org/10.1007/s10549-014-3081-9 ) 25108739 31 Pfisterer K Fusi A Klinghammer K Knodler M Nonnenmacher A