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Tiemo S Gerber, Arno Schad, Nils Hartmann, Erik Springer, Ulrich Zechner and Thomas J Musholt

Blood ETE TCF P53 status 1 m 76 8 III No Mx TT + RAI None Yes Yes Yes 60% Variant 2 w 78 8.5 III Yes Lung, bone TT + RAI Dyspnoea, dysphagia Yes Yes No 90% Wt 3 w 65 7

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Christian Høst, Anders Bojesen, Mogens Erlandsen, Kristian A Groth, Kurt Kristensen, Anne Grethe Jurik, Niels H Birkebæk and Claus H Gravholt

) and lean body mass (g) by dual X-ray densitometry (DEXA) using a Hologic 2000/w osteodensitometer (Hologic, Waltham, MA, USA). The system software provided the mass of lean body, fat and bone mineral for the whole body and specific regions

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Rolf Jorde and Guri Grimnes

importance in calcium metabolism and bone health, vitamin D may potentially also have a number of other health effects. Thus, low serum levels of 25-hydroxyvitamin D (25(OH)D), which is the currently accepted marker of vitamin D status, are associated with

Open access

Henrik Falhammar, Hedi Claahsen-van der Grinten, Nicole Reisch, Jolanta Slowikowska-Hilczer, Anna Nordenström, Robert Roehle, Claire Bouvattier, Baudewijntje P C Kreukels, Birgit Köhler and on behalf of the dsd-LIFE group

scarce. For example, for the rare XY-DSD conditions, almost no data on health status are available except that there is a high prevalence of decreased bone mineral density in CAIS women ( 2 , 3 ). The vast majority of reports have been published on the

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M S Elston, V B Crawford, M Swarbrick, M S Dray, M Head and J V Conaglen

D ). Abnormal bone marrow signal in pelvis and femur was consistent with bony metastases. A technetium-99 m 2,3-dicarboxypropane-1,1-diphosphonate isotope bone scan confirmed the presence of diffuse skeletal metastases and a technetium-99 m -HYNIC

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Samira M Sadowski, Emanuel Christ, Benoit Bédat, Attila Kollár, Wolfram Karenovics, Aurel Perren, Frédéric Triponez and on behalf of the SwissNET registry

. Additionally, 1 patient underwent bone scintigraphy. Those studies resulted in the diagnosis of primary lesions in 72 (66.7%) of the 108 patients who underwent imaging studies. Furthermore, in 3 patients, lymph-nodes were suspected, and 3 patients were

Open access

Josef Köhrle

classical topics such as ‘Pituitary and Hypothalamus’, ‘Thyroid’, ‘Reproduction’, ‘Adrenal Hormones’, ‘Bone and Mineral Metabolism’, ‘Metabolic Syndrome and Diabetes’, ‘Cardiovascular Endocrinology’ and ‘Hormones and Cancer’. These leading experts and their

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Catarina I Gonçalves, José M Aragüés, Margarida Bastos, Luísa Barros, Nuno Vicente, Davide Carvalho and Manuel C Lemos

heterozygous) 3 II-2 M 51 Delayed puberty. Tanner stage 1. Testicular volume 5 mL Normal Low bone mineral density (lumbar spine T -score −2.3; femoral neck T -score −2.8) FSH 1.1 IU/mL (1.0–8.0); LH 0.4 IU/mL (0.7–7.2); total testosterone

Open access

Lauren E Henke, John D Pfeifer, Thomas J Baranski, Todd DeWees and Perry W Grigsby

<0.001  Thyroid only 700 (54.2) 464 (48.6) 236 (70.0) <0.001  Thyroid and cervical LN 548 (42.4) 456 (47.8) 92 (27.3) <0.001  Lung metastases 38 (3.4) 29 (3.0) 9 (2.7) 0.735  Bone metastases 5 (0

Open access

Malachi J McKenna, Barbara F Murray, Myra O'Keane and Mark T Kilbane

to be the group at most risk of hypercalcemia due to overreplacement (29, 30) . For the elderly, meanwhile, a prudent approach to vitamin D supplementation is likely to yield benefits for bone health, ( 9 , http://www.nice.org.uk/guidance/ph56