Leqi He
Leqi He
Department of Clinical Laboratory Medicine, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Xiaoying Li
Xiaoying Li
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Zaoping Chen
Zaoping Chen
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Wei Wang
Wei Wang
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Kai Wang
Kai Wang
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Xinmei Huang
Xinmei Huang
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Qian Yang
Qian Yang
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Wencai Ke
Wencai Ke
Department of Clinical Laboratory Medicine, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Jun Liu
Jun Liu
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Bingbing Zha
Bingbing Zha
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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criteria: (i) miscarriage risk, (ii) iron deficiency, (iii) history of thyroid disease or other chronic diseases (e.g. autoimmune diseases, hypertension, cancer, and diabetes), and (iv) use of oral drugs affecting thyroid function (e.g. traditional Chinese
Bliss Anderson
Bliss Anderson
Department of Endocrinology, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK
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Daniel L Morganstein
Daniel L Morganstein
Department of Endocrinology, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK
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–8% (49) (with anti-PD-1) Seen less commonly in anti-CTLA-4 therapy (8, 9) Anti-thyroid drugs only in Graves’ disease (51, 52, 53, 54, 55) 14–20% (combined therapy) (49, 50) High dose steroids if severe thyroiditis seen (49
Qian Yang
Qian Yang
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Wencai Ke
Wencai Ke
Department of Clinical Laboratory Medicine, Fifth People's Hospital of Shanghai Fudan University, Shanghai, China
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Fanfan Pan
Fanfan Pan
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Xinmei Huang
Xinmei Huang
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Jun Liu
Jun Liu
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Bingbing Zha
Bingbing Zha
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Introduction Graves' disease (GD), also known as an organ-specific autoimmune disorder, is characterized by high radioactive iodine uptake (RAIU) and hyperthyroidism ( 1 ). Excessive production of thyroid hormones results in a substantially
Jiashu Li
Jiashu Li
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, Liaoning, China
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Aihua Liu
Aihua Liu
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, Liaoning, China
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Haixia Liu
Haixia Liu
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, Liaoning, China
Department of Endocrinology and Metabolism, The Second Hospital of Dalian Medical University, Dalian, Liaoning, China
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Department of Endocrinology and Metabolism, The Second Hospital of Dalian Medical University, Dalian, Liaoning, China
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Chenyan Li
Chenyan Li
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, Liaoning, China
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Weiwei Wang
Weiwei Wang
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, Liaoning, China
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Cheng Han
Cheng Han
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, Liaoning, China
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Xinyi Wang
Xinyi Wang
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, Liaoning, China
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Yuanyuan Zhang
Yuanyuan Zhang
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, Liaoning, China
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Weiping Teng
Weiping Teng
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, Liaoning, China
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Zhongyan Shan
Zhongyan Shan
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, Liaoning, China
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of gestation. Gestational age was determined by last menstruation period and ultrasound of fetus. Exclusion criteria applied to multiple pregnancies, patients with thyroid disease history, diabetes, abnormal liver enzymes and any other chronic
Catarina Tavares
Catarina Tavares
Instituto de Investigação e Inovação em Saúde (i3S), Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Medical Faculty of the University of Porto, Porto, Portugal
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Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Medical Faculty of the University of Porto, Porto, Portugal
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Maria João Coelho
Maria João Coelho
Instituto de Investigação e Inovação em Saúde (i3S), Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Institute of Biomedical Sciences of Abel Salazar (ICBAS), Porto, Portugal
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Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Institute of Biomedical Sciences of Abel Salazar (ICBAS), Porto, Portugal
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Catarina Eloy
Catarina Eloy
Instituto de Investigação e Inovação em Saúde (i3S), Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Medical Faculty of the University of Porto, Porto, Portugal
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Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Medical Faculty of the University of Porto, Porto, Portugal
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Miguel Melo
Miguel Melo
Instituto de Investigação e Inovação em Saúde (i3S), Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Department of Endocrinology, Diabetes and Metabolism, University and Hospital Center of Coimbra, Coimbra, Portugal
Medical Faculty, University of Coimbra, Coimbra, Portugal
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Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Department of Endocrinology, Diabetes and Metabolism, University and Hospital Center of Coimbra, Coimbra, Portugal
Medical Faculty, University of Coimbra, Coimbra, Portugal
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Adriana Gaspar da Rocha
Adriana Gaspar da Rocha
Instituto de Investigação e Inovação em Saúde (i3S), Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Public Health Unit, ACeS Baixo Mondego, Coimbra, Portugal
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Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Public Health Unit, ACeS Baixo Mondego, Coimbra, Portugal
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Ana Pestana
Ana Pestana
Instituto de Investigação e Inovação em Saúde (i3S), Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Medical Faculty of the University of Porto, Porto, Portugal
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Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Medical Faculty of the University of Porto, Porto, Portugal
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Rui Batista
Rui Batista
Instituto de Investigação e Inovação em Saúde (i3S), Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Medical Faculty of the University of Porto, Porto, Portugal
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Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Medical Faculty of the University of Porto, Porto, Portugal
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Luciana Bueno Ferreira
Luciana Bueno Ferreira
Instituto de Investigação e Inovação em Saúde (i3S), Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Medical Faculty of the University of Porto, Porto, Portugal
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Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Medical Faculty of the University of Porto, Porto, Portugal
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Elisabete Rios
Elisabete Rios
Instituto de Investigação e Inovação em Saúde (i3S), Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Medical Faculty of the University of Porto, Porto, Portugal
Department of Pathology, Medical Faculty of the University of Porto, Porto, Portugal
Department of Pathology, Hospital de S. João, Porto, Portugal
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Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Medical Faculty of the University of Porto, Porto, Portugal
Department of Pathology, Medical Faculty of the University of Porto, Porto, Portugal
Department of Pathology, Hospital de S. João, Porto, Portugal
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Samia Selmi-Ruby
Samia Selmi-Ruby
Inserm UMR-S1052, CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon, Lyon, France
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Bruno Cavadas
Bruno Cavadas
Instituto de Investigação e Inovação em Saúde (i3S), Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Institute of Biomedical Sciences of Abel Salazar (ICBAS), Porto, Portugal
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Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Institute of Biomedical Sciences of Abel Salazar (ICBAS), Porto, Portugal
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Luísa Pereira
Luísa Pereira
Instituto de Investigação e Inovação em Saúde (i3S), Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Medical Faculty of the University of Porto, Porto, Portugal
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Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Medical Faculty of the University of Porto, Porto, Portugal
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Manuel Sobrinho Simões
Manuel Sobrinho Simões
Instituto de Investigação e Inovação em Saúde (i3S), Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Medical Faculty of the University of Porto, Porto, Portugal
Department of Pathology, Medical Faculty of the University of Porto, Porto, Portugal
Department of Pathology, Hospital de S. João, Porto, Portugal
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Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Medical Faculty of the University of Porto, Porto, Portugal
Department of Pathology, Medical Faculty of the University of Porto, Porto, Portugal
Department of Pathology, Hospital de S. João, Porto, Portugal
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Paula Soares
Paula Soares
Instituto de Investigação e Inovação em Saúde (i3S), Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Medical Faculty of the University of Porto, Porto, Portugal
Department of Pathology, Medical Faculty of the University of Porto, Porto, Portugal
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Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Medical Faculty of the University of Porto, Porto, Portugal
Department of Pathology, Medical Faculty of the University of Porto, Porto, Portugal
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-driven PTCs, with RAS -like PTCs having relatively high thyroid differentiation score ( 30 ). Our results on the immunohistochemical NIS expression in normal thyroid and Graves’ disease (an autoimmune condition known to express high levels of NIS) ( 42
Avinaash Maharaj
Avinaash Maharaj
Centre for Endocrinology, John Vane Science Centre, Queen Mary University of London, London, UK
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Ruth Kwong
Ruth Kwong
Centre for Endocrinology, John Vane Science Centre, Queen Mary University of London, London, UK
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Jack Williams
Jack Williams
Centre for Endocrinology, John Vane Science Centre, Queen Mary University of London, London, UK
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Christopher Smith
Christopher Smith
Centre for Endocrinology, John Vane Science Centre, Queen Mary University of London, London, UK
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Helen Storr
Helen Storr
Centre for Endocrinology, John Vane Science Centre, Queen Mary University of London, London, UK
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Ruth Krone
Ruth Krone
Birmingham Children’s Hospital, Birmingham, UK
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Debora Braslavsky
Debora Braslavsky
Centro de Investigaciones Endocrinológicas ‘Dr. Cesar Bergadá’ (CEDIE) – CONICET – FEI – División de Endocrinología, Hospital de Niños ‘Ricardo Gutiérrez’, Buenos Aires, Argentina
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Maria Clemente
Maria Clemente
Paediatric Endocrinology, Growth and Development Research Unit, Vall d’Hebron Research Institute (VHIR), Hospital Vall d’Hebron, CIBERER, Instituto de Salud Carlos III, Barcelona, Spain
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Nanik Ram
Nanik Ram
Department of Endocrinology, The Aga Khan University Hospital, Karachi, Pakistan
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Indraneel Banerjee
Indraneel Banerjee
Department of Paediatric Endocrinology, Royal Manchester Children’s Hospital, Manchester, UK
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Semra Çetinkaya
Semra Çetinkaya
Health Sciences University, Dr. Sami Ulus Obstetrics and Gynaecology, Children’s Health and Disease Education and Research Hospital, Ankara, Turkey
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Federica Buonocore
Federica Buonocore
Genetics and Genomic Medicine Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK
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Tülay Güran
Tülay Güran
Department of Paediatric Endocrinology and Diabetes, Marmara University, School of Medicine, Istanbul, Turkey
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John C Achermann
John C Achermann
Genetics and Genomic Medicine Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK
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Louise Metherell
Louise Metherell
Centre for Endocrinology, John Vane Science Centre, Queen Mary University of London, London, UK
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Rathi Prasad
Rathi Prasad
Centre for Endocrinology, John Vane Science Centre, Queen Mary University of London, London, UK
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including renal disease and endocrinopathy ultimately affect growth, particularly if identified late or not adequately treated. The constellation of adrenal, gonadal and thyroid disease is described in one other non-autoimmune-inherited form of adrenal
Hana Vítková
Hana Vítková
Third Department of Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic
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Kateřina Anderlová
Kateřina Anderlová
Third Department of Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic
Department of Gynaecology, Obstetrics and Neonatology, First Faculty of Medicine Charles University and General University Hospital in Prague, Prague, Czech Republic
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Department of Gynaecology, Obstetrics and Neonatology, First Faculty of Medicine Charles University and General University Hospital in Prague, Prague, Czech Republic
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Jan Krátký
Jan Krátký
Third Department of Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic
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Radovan Bílek
Radovan Bílek
Institute of Endocrinology, Prague, Czech Republic
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Drahomíra Springer
Drahomíra Springer
Institute of Clinical Biochemistry and Laboratory Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic
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Felix Votava
Felix Votava
Department of Children and Adolescents, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Prague, Czech Republic
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Tomáš Brutvan
Tomáš Brutvan
Third Department of Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic
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Adéla Krausová
Adéla Krausová
Third Department of Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic
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Kristýna Žabková
Kristýna Žabková
Third Department of Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic
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Eliška Potluková
Eliška Potluková
University Center of Internal Medicine, Cantonal Hospital Baselland and University of Basel, Switzerland
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Jan Jiskra
Jan Jiskra
Third Department of Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic
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concentrations were collected, and all women completed a questionnaire focusing on a personal history of thyroid diseases, autoimmune and other diseases, medication, and iodine use during pregnancy. Women with GDM were followed, and data on diabetes compensation
Sílvia Santos Monteiro
Sílvia Santos Monteiro
Division of Endocrinology, Diabetes and Metabolism. Department of Medicine, Centro Hospitalar Universitário do Porto, Largo Professor Abel Salazar Porto, Portugal
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Tiago Silva Santos
Tiago Silva Santos
Division of Endocrinology, Diabetes and Metabolism. Department of Medicine, Centro Hospitalar Universitário do Porto, Largo Professor Abel Salazar Porto, Portugal
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Ana Martins Lopes
Ana Martins Lopes
Division of Endocrinology, Diabetes and Metabolism. Department of Medicine, Centro Hospitalar Universitário do Porto, Largo Professor Abel Salazar Porto, Portugal
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José Carlos Oliveira
José Carlos Oliveira
Department of Clinical Pathology, Centro Hospitalar Universitário do Porto, Largo Professor Abel Salazar Porto, Portugal
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Cláudia Freitas
Cláudia Freitas
Division of Endocrinology, Diabetes and Metabolism. Department of Medicine, Centro Hospitalar Universitário do Porto, Largo Professor Abel Salazar Porto, Portugal
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André Couto Carvalho
André Couto Carvalho
Division of Endocrinology, Diabetes and Metabolism. Department of Medicine, Centro Hospitalar Universitário do Porto, Largo Professor Abel Salazar Porto, Portugal
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.0 0.91 Postsurgical Celiac disease None None I 62 88.0 29.4 3.4 33.5 0.85 Postsurgical H. pylori infection H. pylori gastritis; ‘intestinal surgery’ PPI; CC J 52 82.0 30.6 3.1 6.0 1.61 Autoimmune
Ru-Xuan Zhao
Ru-Xuan Zhao
Department of Endocrinology, Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Ting-Ting Shi
Ting-Ting Shi
Department of Endocrinology, Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Sha Luo
Sha Luo
Department of Nuclear Medicine, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Yun-Fu Liu
Yun-Fu Liu
Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Zhong Xin
Zhong Xin
Department of Endocrinology, Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Jin-Kui Yang
Jin-Kui Yang
Department of Endocrinology, Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Introduction Graves’ orbitopathy (GO) is an autoimmune disease which frequently arises in patients suffering from Graves’ disease ( 1 , 2 ). GO, often involving both eyes, is one of the most common orbital diseases in adults ( 3 , 4 ). GO
Yue-Yue Wang
Yue-Yue Wang
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Qian Wu
Qian Wu
Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Lu Chen
Lu Chen
Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Wen Chen
Wen Chen
Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Tao Yang
Tao Yang
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Xiao-Quan Xu
Xiao-Quan Xu
Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Fei-Yun Wu
Fei-Yun Wu
Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Hao Hu
Hao Hu
Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Huan-Huan Chen
Huan-Huan Chen
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Introduction Thyroid-associated ophthalmopathy (TAO) is an autoimmune and inflammatory orbital disease ( 1 ). The natural course of TAO is composed of an initial active stage and a later static stage. Systemic immunosuppressive treatment is
