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Dario de Biase Department of Pharmacy and Biotechnology (Dipartimento di Farmacia e Biotecnologie) – Molecular Diagnostic Unit, Azienda USL di Bologna, University of Bologna, Bologna, Italy

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Federica Torricelli Laboratory of Translational Research, Azienda Unità Sanitaria Locale AUSL-IRCCS, Reggio Emilia, Italy

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Moira Ragazzi Pathology Unit, Azienda Unità Sanitaria Locale AUSL-IRCCS, Reggio Emilia, Italy

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Benedetta Donati Laboratory of Translational Research, Azienda Unità Sanitaria Locale AUSL-IRCCS, Reggio Emilia, Italy

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Elisabetta Kuhn Pathology Unit, Azienda Unità Sanitaria Locale AUSL-IRCCS, Reggio Emilia, Italy

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Michela Visani Department of Medicine (Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale) – Molecular Diagnostic Unit, Azienda USL di Bologna, University of Bologna School of Medicine, Bologna, Italy

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Giorgia Acquaviva Department of Medicine (Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale) – Molecular Diagnostic Unit, Azienda USL di Bologna, University of Bologna School of Medicine, Bologna, Italy

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Annalisa Pession Department of Pharmacy and Biotechnology (Dipartimento di Farmacia e Biotecnologie) – Molecular Diagnostic Unit, Azienda USL di Bologna, University of Bologna, Bologna, Italy

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Giovanni Tallini Department of Medicine (Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale) – Molecular Diagnostic Unit, Azienda USL di Bologna, University of Bologna School of Medicine, Bologna, Italy

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Simonetta Piana Pathology Unit, Azienda Unità Sanitaria Locale AUSL-IRCCS, Reggio Emilia, Italy

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Alessia Ciarrocchi Laboratory of Translational Research, Azienda Unità Sanitaria Locale AUSL-IRCCS, Reggio Emilia, Italy

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on supplementary data given at the end of this article). Table 1 Clinicopathological features of cases analyzed by NGS. Group Num of cases Age (mean) (years) Sex Histology Fu (range) FU (event) DM-PTC 29 53

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Jakob Høgild Langdahl Department of Clinical Genetics, Odense University Hospital, Odense, Denmark
Institute of Clinical Research, University of Southern Denmark, Odense, Denmark
Department of Endocrinology, Hospital of Southwest Jutland, Esbjerg, Denmark

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Anja Lisbeth Frederiksen Department of Clinical Genetics, Odense University Hospital, Odense, Denmark
Institute of Clinical Research, University of Southern Denmark, Odense, Denmark

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John Vissing Copenhagen Neuromuscular Center, Department of Neurology, Rigshospitalet, Copenhagen, Denmark

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Morten Frost Institute of Clinical Research, University of Southern Denmark, Odense, Denmark
Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark

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Knud Bonnet Yderstræde Institute of Clinical Research, University of Southern Denmark, Odense, Denmark
Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark

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Per Heden Andersen Department of Endocrinology, Hospital of Southwest Jutland, Esbjerg, Denmark

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BIGTT study ( 28 ) to calculate the insulin sensitivity index (BIGTT-S 1 ) and acute insulin response index (BIGTT-AIR). Differences between carriers and controls were compared for each measurement by unpaired Student’s t test or Mann–Whitney U test

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Anru Wang Department of Pediatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Department of Pediatrics, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China

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Xueqin Yan Department of Pediatrics, Boai Hospital of Zhongshan, Zhongshan, China

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Cai Zhang Department of Pediatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Caiqi Du Department of Pediatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Wenjun Long Department of Pediatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Di Zhan Department of Pediatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Xiaoping Luo Department of Pediatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Introduction The worldwide prevalence of obesity among children and adolescents has increased in past years ( 1 ). Obesity is associated with insulin resistance, type 2 diabetes mellitus (T2DM) and long-term cardiovascular complications

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Hoda Gad Department of Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar

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Einas Elgassim Department of Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar

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Ibrahim Mohammed Department of Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar
Department of Internal Medicine, Albany Medical Center Hospital, Albany, New York, USA

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Ahmad Yaser Alhaddad Department of Mechanical and Industrial Engineering, Qatar University, Doha, Qatar

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Hussein Ahmed Hussein Zaky Aly KINDI Center for computing research, Qatar University, Doha, Qatar

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John-John Cabibihan Department of Mechanical and Industrial Engineering, Qatar University, Doha, Qatar

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Abdulaziz Al-Ali KINDI Center for computing research, Qatar University, Doha, Qatar

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Kishor Kumar Sadasivuni Center for Advanced Materials, Qatar University, Doha, Qatar

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Aliyaa Haji Department of Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar

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Neila Lamine Department of Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar

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Adnan Khan Faculty of Healthy Sciences, Khyber Medical University, Peshawar, Pakistan

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Ioannis N Petropoulos Department of Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar

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Georgios Ponirakis Department of Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar

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Alise Kalteniece Institute of Cardiovascular Medicine, University of Manchester, Manchester, UK

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Maryam Ferdousi Institute of Cardiovascular Medicine, University of Manchester, Manchester, UK

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Shazli Azmi Institute of Cardiovascular Medicine, University of Manchester, Manchester, UK

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Uazman Alam Diabetes and Neuropathy Research, Department of Eye and Vision Sciences and Pain Research Institute, Institute of Ageing and Chronic Disease, University of Liverpool and Aintree University Hospital NHS Foundation Trust, Liverpool, UK
Department of Diabetes and Endocrinology, Royal Liverpool and Broadgreen University NHS Hospital Trust, Liverpool, UK
Division of Endocrinology, Diabetes and Gastroenterology, University of Manchester, Manchester, UK

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Wajeeha Abuhelaiqa Hamad Medical Corporation, National Diabetes Center, Doha, Qatar

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Amin Jayyousi Hamad Medical Corporation, National Diabetes Center, Doha, Qatar

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Dabia AlMohanadi Hamad Medical Corporation, National Diabetes Center, Doha, Qatar

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Khaled Baagar Hamad Medical Corporation, National Diabetes Center, Doha, Qatar

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Rayaz A Malik Department of Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar
Institute of Cardiovascular Medicine, University of Manchester, Manchester, UK

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Introduction Diabetic peripheral neuropathy (DPN) affects ~50% of people with diabetes mellitus (T1DM) and (T2DM) ( 1 , 2 ). It has an insidious onset, which can lead to painful diabetic neuropathy, erectile dysfunction, foot ulceration and

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Liangming Li Center for Scientific Research and Institute of Exercise and Health, Guangzhou Sport University, Guangzhou, China
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Yuan Wei Center for Scientific Research and Institute of Exercise and Health, Guangzhou Sport University, Guangzhou, China
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Chunlu Fang Center for Scientific Research and Institute of Exercise and Health, Guangzhou Sport University, Guangzhou, China
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Shujing Liu Center for Scientific Research and Institute of Exercise and Health, Guangzhou Sport University, Guangzhou, China
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Fu Zhou Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Ge Zhao Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Yaping Li Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Yuan Luo Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Ziyi Guo Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Weiqun Lin Department of Clinical Nutrition, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China

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Wenqi Yang Center for Scientific Research and Institute of Exercise and Health, Guangzhou Sport University, Guangzhou, China
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Introduction Type 2 diabetes mellitus (T2DM) has become a pandemic and a major global health problem. Obesity, which has a rapidly increasing prevalence, is considered to be a primary cause of T2DM ( 1 , 2 ). Approximately 60%-90% of patients

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Xiang Hu Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Qiao Zhang Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Tian-Shu Zeng Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Jiao-Yue Zhang Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Jie Min Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Sheng-Hua Tian Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Hantao Huang Yiling Hospital, Yichang, China

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Miaomiao Peng Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Nan Zhang Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Mengjiao Li Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Qing Wan Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Fei Xiao Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Yan Chen Institute of Big Data and Internet Innovation, Hunan University of Commerce, Changsha, China

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Chaodong Wu Department of Nutrition and Food Science, Texas A&M University, College Station, Texas, USA

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Lu-Lu Chen Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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prediabetes. Thus, we were not able to provide the data in this investigation. Table 1 Prediabetes and diabetes prevalence and rate of diagnosis. The proportion in total participants The proportion in DM Normal Prediabetes DM

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Bharat Kumar All India Institute of Medical Sciences, Jodhpur, Rajasthan, India

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Madhukar Mittal All India Institute of Medical Sciences, Jodhpur, Rajasthan, India

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Maya Gopalakrishnan All India Institute of Medical Sciences, Jodhpur, Rajasthan, India

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Mahendra K Garg All India Institute of Medical Sciences, Jodhpur, Rajasthan, India

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Sanjeev Misra All India Institute of Medical Sciences, Jodhpur, Rajasthan, India

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( 32 ). The majority of DKA cases worldwide occur in patients with T2DM due to its higher prevalence, although ketoacidosis is typically associated with T1DM ( 33 ). A similar pattern has been observed in patients with COVID-19 in a systematic review

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Zherui Fu Department of Emergency, The First People’s Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China

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Yi Lai Department of Emergency, The First People’s Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China

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Qianfei Wang Department of Emergency, The First People’s Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China

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Feng Lin Department of Orthopedics, The First People's Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China

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Jiaping Fang Department of Emergency, The First People’s Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China

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.3%)  Female 185 (36.1%) 188 (36.7%) Age, n (%) 0.063  ≤45 111 (21.7%) 132 (25.8%)  >45 145 (28.3%) 124 (24.2%) Pathologic T stage, n (%) 0.554  T1 72 (14.1%) 71 (13.9%)  T2 91 (17

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Satoshi Higuchi Department of Diagnostic Radiology, Tohoku University Hospital, Sendai, Miyagi, Japan

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Hideki Ota Department of Diagnostic Radiology, Tohoku University Hospital, Sendai, Miyagi, Japan
Department of Advanced MRI Collaboration Research, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan

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Yuta Tezuka Division of Nephrology, Endocrinology and Vascular Medicine, Department of Medicine, Tohoku University Hospital, Sendai, Miyagi, Japan
Department of Radiology, The University of British Columbia, Vancouver, Canada

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Kazumasa Seiji Department of Diagnostic Radiology, Tohoku University Hospital, Sendai, Miyagi, Japan

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Hidenobu Takagi Department of Diagnostic Radiology, Tohoku University Hospital, Sendai, Miyagi, Japan
Department of Radiology, The University of British Columbia, Vancouver, Canada

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Jongmin Lee Department of Radiology, School of Medicine, Kyungpook National University, Daegu, Korea

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Yi-Wei Lee Department of Radiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan

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Kei Omata Division of Nephrology, Endocrinology and Vascular Medicine, Department of Medicine, Tohoku University Hospital, Sendai, Miyagi, Japan
Department of Radiology, The University of British Columbia, Vancouver, Canada

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Yoshikiyo Ono Division of Nephrology, Endocrinology and Vascular Medicine, Department of Medicine, Tohoku University Hospital, Sendai, Miyagi, Japan
Department of Radiology, The University of British Columbia, Vancouver, Canada

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Ryo Morimoto Division of Nephrology, Endocrinology and Vascular Medicine, Department of Medicine, Tohoku University Hospital, Sendai, Miyagi, Japan

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Masataka Kudo Division of Nephrology, Endocrinology and Vascular Medicine, Department of Medicine, Tohoku University Hospital, Sendai, Miyagi, Japan

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Fumitoshi Satoh Division of Nephrology, Endocrinology and Vascular Medicine, Department of Medicine, Tohoku University Hospital, Sendai, Miyagi, Japan
Division of Clinical Hypertension, Endocrinology and Metabolism, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan

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Kei Takase Department of Diagnostic Radiology, Tohoku University Hospital, Sendai, Miyagi, Japan

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275 – 2 86 . ( https://doi.org/10.1148/radiol.2019190651 ) 30 Banypersad SM Fontana M Maestrini V Sado DM Captur G Petrie A Piechnik SK Whelan CJ Herrey AS Gillmoreet JD T1 mapping and survival in systemic light

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Xiaoxia Jia Center for Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Yaxin An Center for Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Yuechao Xu Center for Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Yuxian Yang Center for Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Chang Liu Center for Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Dong Zhao Center for Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Jing Ke Center for Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Introduction Osteoporosis and related fractures commonly exist in patients with type 2 diabetes mellitus (T2DM), which results in a great economic and social burden in the aging society ( 1 ). It has been reported that diabetes mellitus was an

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