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children and adolescents ( 1 ). The estimated incidence of type 1 diabetes per 100,000 persons years for all ages in China was 1.01 ( 2 ). However, the mean annual age-standardized incidence of type 2 diabetes in youth aged 5–19 years was 1
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. ( 25 ) found that 143 lipid molecules were expressed differently between the SCH and control groups. A study ( 26 ) about fatty acids and SCH showed that there was a correlation between serum fatty acid composition and pregnant Chinese women with SCH
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Introduction Estimated pulse wave velocity with arterial stiffness Radial arterial pulsation is a vital indicator in ancient Chinese that allowed experienced traditional practitioners to examine their patients. The ancient Chinese
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Introduction A genome-wide association study in Chinese population has shown that there is marked reduction in microbiota diversity in patients with T2DM. The main flora of the T2DM patients is characterized by an increase in mucus
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. Methods and materials Description of the cohort KTRs who underwent their first kidney transplant in West China Hospital between June 2020 and December 2020 were recruited as a prospective cohort to study the impacts of vitamin D supplementation on
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) were obtained from Shanghai Laboratory Animal Center (Shanghai, China) and used in the current study as the GDM mouse model ( 27 ). The animals were housed under standard rearing conditions (12 h light:12 h darkness cycle), and allowed access to food
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, cleared, covered and measured under a light microscope equipped with a digital camera (DM4000B, Leica). For immunofluorescence, sections of adipose tissue were treated with rabbit anti-TFAM (Mitochondrial Transcription Factor A, 1:50; Bioss, Beijing, China
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Animal Care and Use Committee of the Chaohu University (Anhui China). Treadmill exercise protocol Before beginning the formal 10-week exercise protocol, animals were familiarized to treadmill running (5–20 min/day) for five consecutive days. After
Key Laboratory of Medical Imaging of Gansu Province, Lanzhou, China
Second Clinical School, Lanzhou University, Lanzhou, China
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Key Laboratory of Medical Imaging of Gansu Province, Lanzhou, China
Second Clinical School, Lanzhou University, Lanzhou, China
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Key Laboratory of Medical Imaging of Gansu Province, Lanzhou, China
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Key Laboratory of Medical Imaging of Gansu Province, Lanzhou, China
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Key Laboratory of Medical Imaging of Gansu Province, Lanzhou, China
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Key Laboratory of Medical Imaging of Gansu Province, Lanzhou, China
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of these two tumors. Materials and methods Patients For this retrospective analysis, ethical approval was obtained from the Institutional Review Board of Lanzhou University Second Hospital (Lanzhou, China), and the need for informed
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, China) and infected KGN cells according to the instructions. To knockdown NEDD4L, si-NEDD4L was transfected into KGN cells by using Lipofectamine 3000. Briefly, KGN cells were transfected with 20 nM of si-NEDD4L (AGUCAUAAAUCUCGAGUCA) or si-control RNA