Marc Blondon
Marc Blondon
Division of Angiology and Hemostasis, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland
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Emmanuel Biver
Emmanuel Biver
Division of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland
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Olivia Braillard
Olivia Braillard
Division of Primary Care Medicine, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland
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Marc Righini
Marc Righini
Division of Angiology and Hemostasis, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland
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Pierre Fontana
Pierre Fontana
Division of Angiology and Hemostasis, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland
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Alessandro Casini
Alessandro Casini
Division of Angiology and Hemostasis, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland
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collection. Most variables, including race, smoking, fractures, and menopause status, were self-reported. The electronic medical chart, including all laboratory results, was extracted to evaluate for the presence of co-morbidities and prescribed medications
A Gizard
A Gizard
Department of Pediatric Orthopedic Surgery, Besançon University Hospital, Paris, France
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A Rothenbuhler
A Rothenbuhler
APHP, Department of Pediatric Endocrinology, Bicêtre Paris Sud, Le Kremlin Bicêtre, France
Reference Center for Rare Disorders of Calcium and Phosphate Metabolism, Le Kremlin Bicêtre, France
Plateforme d’Expertise Paris Sud Maladies Rares and Filière OSCAR, Bicêtre Paris Sud, Le Kremlin Bicêtre, France
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Reference Center for Rare Disorders of Calcium and Phosphate Metabolism, Le Kremlin Bicêtre, France
Plateforme d’Expertise Paris Sud Maladies Rares and Filière OSCAR, Bicêtre Paris Sud, Le Kremlin Bicêtre, France
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Z Pejin
Z Pejin
APHP, Department of Pediatric Orthopedic Surgery, Necker Hospital, Paris, France
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G Finidori
G Finidori
APHP, Department of Pediatric Orthopedic Surgery, Necker Hospital, Paris, France
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C Glorion
C Glorion
APHP, Department of Pediatric Orthopedic Surgery, Necker Hospital, Paris, France
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B de Billy
B de Billy
Department of Pediatric Orthopedic Surgery, Besançon University Hospital, Paris, France
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A Linglart
A Linglart
APHP, Department of Pediatric Endocrinology, Bicêtre Paris Sud, Le Kremlin Bicêtre, France
Reference Center for Rare Disorders of Calcium and Phosphate Metabolism, Le Kremlin Bicêtre, France
Plateforme d’Expertise Paris Sud Maladies Rares and Filière OSCAR, Bicêtre Paris Sud, Le Kremlin Bicêtre, France
INSERM U1169, Hôpital Bicêtre, Le Kremlin Bicêtre, et Université Paris-Saclay, Le Kremlin Bicêtre, France
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Reference Center for Rare Disorders of Calcium and Phosphate Metabolism, Le Kremlin Bicêtre, France
Plateforme d’Expertise Paris Sud Maladies Rares and Filière OSCAR, Bicêtre Paris Sud, Le Kremlin Bicêtre, France
INSERM U1169, Hôpital Bicêtre, Le Kremlin Bicêtre, et Université Paris-Saclay, Le Kremlin Bicêtre, France
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P Wicart
P Wicart
Reference Center for Rare Disorders of Calcium and Phosphate Metabolism, Le Kremlin Bicêtre, France
APHP, Department of Pediatric Orthopedic Surgery, Necker Hospital, Paris, France
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APHP, Department of Pediatric Orthopedic Surgery, Necker Hospital, Paris, France
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fractures ( 6 , 15 , 17 ). The main aims of our retrospective multicenter study were 1- to evaluate the long-term results of the orthopedic surgery performed during childhood in XLHR patients and 2- to identify factors predictive of the course
M Boering
M Boering
Isala, Diabetes Centre, Zwolle, The Netherlands
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P R van Dijk
P R van Dijk
Isala, Diabetes Centre, Zwolle, The Netherlands
Isala, Department of Internal Medicine, Zwolle, The Netherlands
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Isala, Department of Internal Medicine, Zwolle, The Netherlands
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S J J Logtenberg
S J J Logtenberg
Diakonessenhuis, Department of Internal Medicine, Utrecht, The Netherlands
Langerhans Medical Research group, Zwolle, The Netherlands
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Langerhans Medical Research group, Zwolle, The Netherlands
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K H Groenier
K H Groenier
Isala, Diabetes Centre, Zwolle, The Netherlands
Department of General Practice, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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Department of General Practice, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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B H R Wolffenbuttel
B H R Wolffenbuttel
Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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R O B Gans
R O B Gans
Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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N Kleefstra
N Kleefstra
Isala, Diabetes Centre, Zwolle, The Netherlands
Langerhans Medical Research group, Zwolle, The Netherlands
Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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Langerhans Medical Research group, Zwolle, The Netherlands
Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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H J G Bilo
H J G Bilo
Isala, Diabetes Centre, Zwolle, The Netherlands
Isala, Department of Internal Medicine, Zwolle, The Netherlands
Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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Isala, Department of Internal Medicine, Zwolle, The Netherlands
Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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, 27 , 28 ). Alterations found in SHBG and testosterone concentrations might be associated with disorders with an increased incidence among T1DM patients such as reproductive disorders, PCOS, increased risk of osteoporotic fractures in females, and a
Dafydd Aled Rees
Dafydd Aled Rees
Cardiff University, Cardiff, United Kingdom
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Deborah P Merke
Deborah P Merke
National Institutes of Health Clinical Center and the Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, USA
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Wiebke Arlt
Wiebke Arlt
MRC LMS, London, United Kingdom
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Aude Brac De La Perriere
Aude Brac De La Perriere
Hospices Civils de Lyon - GHE - Endocrinologie, Bron, France
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Angelica Linden Hirschberg
Angelica Linden Hirschberg
Karolinska Institute, Solna, Sweden
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Anders Juul
Anders Juul
Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark, and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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John Newell-Price
John Newell-Price
The University of Sheffield, Sheffield, United Kingdom
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Alessandro Prete
Alessandro Prete
University of Birmingham, Birmingham, United Kingdom
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Nicole Reisch
Nicole Reisch
Endokrinologie, Nephrologie und weitere Sektionen - Medizinische Klinik und Poliklinik IV - Campus Innenstadt, München, Germany
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Nike M Stikkelbroeck
Nike M Stikkelbroeck
Radboud University Nijmegen, Nijmegen, Netherlands
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Philippe A Touraine
Philippe A Touraine
University Hospitals Pitié Salpêtrière - Charles Foix, Paris, France
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Alex Lewis
Alex Lewis
Neurocrine Biosciences Inc, London, United Kingdom
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John Porter
John Porter
Neurocrine Biosciences Inc, London, United Kingdom
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Helen Coope
Helen Coope
Neurocrine Biosciences Inc, London, United Kingdom
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Richard J Ross
Richard J Ross
The University of Sheffield, Sheffield, United Kingdom
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glucocorticoid dose than hydrocortisone and a significantly lower final height. Metabolic outcomes were variably reported, with some studies reporting lower cardiovascular risk factors on prednisolone but a higher incidence of osteoporosis and fractures ( 16
Aleksandra Gilis-Januszewska
Aleksandra Gilis-Januszewska
Chair and Department of Endocrinology, Jagiellonian University Medical College, Krakow, Poland
Endocrinology Department, University Hospital in Krakow, Krakow, Poland
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Endocrinology Department, University Hospital in Krakow, Krakow, Poland
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Łukasz Kluczyński
Łukasz Kluczyński
Chair and Department of Endocrinology, Jagiellonian University Medical College, Krakow, Poland
Endocrinology Department, University Hospital in Krakow, Krakow, Poland
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Endocrinology Department, University Hospital in Krakow, Krakow, Poland
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Alicja Hubalewska-Dydejczyk
Alicja Hubalewska-Dydejczyk
Chair and Department of Endocrinology, Jagiellonian University Medical College, Krakow, Poland
Endocrinology Department, University Hospital in Krakow, Krakow, Poland
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Endocrinology Department, University Hospital in Krakow, Krakow, Poland
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in acute conditions and provides better visualization of skull fractures, MRI is far superior for assessment of intracranial hematomas, contusion, and shearing injuries, with an estimated sensitivity of 96.4% (compared to a sensitivity of 63.4% for CT
Jothydev Kesavadev
Jothydev Kesavadev
Jothydev’s Diabetes Research Centre, Trivandrum, Kerala, India
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Pradeep Babu Sadasivan Pillai
Pradeep Babu Sadasivan Pillai
Jothydev’s Diabetes Research Centre, Trivandrum, Kerala, India
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Arun Shankar
Arun Shankar
Jothydev’s Diabetes Research Centre, Trivandrum, Kerala, India
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Gopika Krishnan
Gopika Krishnan
Jothydev’s Diabetes Research Centre, Trivandrum, Kerala, India
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Sunitha Jothydev
Sunitha Jothydev
Jothydev’s Diabetes Research Centre, Trivandrum, Kerala, India
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decline in beta-cell function. SU can lose their effectiveness over time, while TZDs increase the risk of fracture and cardiac failure. Hence, new treatment options are sought. One recent approach is to target the incretin mimetic hormone GLP-1. GLP-1 is
S Westra
S Westra
Department of Internal Medicine, Medical Centre Alkmaar, Alkmaar, the Netherlands
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Y H M Krul-Poel
Y H M Krul-Poel
Department of Internal Medicine, Medical Centre Alkmaar, Alkmaar, the Netherlands
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H J van Wijland
H J van Wijland
Department of General Practice, DIAZON, Alkmaar, the Netherlands
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M M ter Wee
M M ter Wee
Department of Epidemiology and Biostatistics, VU Medical Centre, Amsterdam, the Netherlands
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F Stam
F Stam
Department of Internal Medicine, Medical Centre Alkmaar, Alkmaar, the Netherlands
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P Lips
P Lips
Department of Internal Medicine, Endocrine Section, VU Medical Centre, Amsterdam, the Netherlands
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F Pouwer
F Pouwer
Department of Medical and Clinical Psychology, Tilburg University, Tilburg, the Netherlands
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S Simsek
S Simsek
Department of Internal Medicine, Medical Centre Alkmaar, Alkmaar, the Netherlands
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component summary or mental component summary in elderly people >70 years with previous low trauma osteoporotic fracture using the SF-12 (shortened version of the SF-36) after 24–62 months of follow-up ( 29 ). Moreover, one recent double-blind, placebo
Mieke Van Hemelrijck
Mieke Van Hemelrijck
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Thurkaa Shanmugalingam
Thurkaa Shanmugalingam
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Cecilia Bosco
Cecilia Bosco
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Wahyu Wulaningsih
Wahyu Wulaningsih
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Sabine Rohrmann
Sabine Rohrmann
Cancer Epidemiology Group, Division of Chronic Disease Epidemiology, Division of Cancer Studies, King's College London, London, UK
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renal production of vitamin D, which increases calcium availability (5) . Low IGF1 levels have been linked to bone loss and risk of fracture (37, 38) . We found a positive association between IGF1 and IGFBP3 with calcium in those with normal BMD of the
Johanna Christina Penell
Johanna Christina Penell
Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden
Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden
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Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden
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Mark M Kushnir
Mark M Kushnir
Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA
ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA
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ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA
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Lars Lind
Lars Lind
Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden
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Jonatan Bergquist
Jonatan Bergquist
Department of Chemistry – BMC, Analytical Chemistry, Uppsala University, Uppsala, Sweden
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Jonas Bergquist
Jonas Bergquist
Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA
Department of Chemistry – BMC, Analytical Chemistry, Uppsala University, Uppsala, Sweden
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Department of Chemistry – BMC, Analytical Chemistry, Uppsala University, Uppsala, Sweden
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P Monica Lind
P Monica Lind
Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden
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Tord Naessen
Tord Naessen
Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden
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Associations between low levels of serum estradiol, bone density, and fractures among elderly women: the study of osteoporotic fractures . Journal of Clinical Endocrinology and Metabolism 1998 83 2239 – 2243 . ( https://doi.org/10.1210/jcem.83
Cheng Han Ng
Cheng Han Ng
Yong Loo Lin School of Medicine, National University of Singapore, Singapore
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Yip Han Chin
Yip Han Chin
Yong Loo Lin School of Medicine, National University of Singapore, Singapore
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Marcus Hon Qin Tan
Marcus Hon Qin Tan
Yong Loo Lin School of Medicine, National University of Singapore, Singapore
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Jun Xuan Ng
Jun Xuan Ng
Yong Loo Lin School of Medicine, National University of Singapore, Singapore
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Samantha Peiling Yang
Samantha Peiling Yang
Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Department of Medicine, National University Hospital, Singapore
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Department of Medicine, National University Hospital, Singapore
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Jolene Jiayu Kiew
Jolene Jiayu Kiew
Department of Medicine, National University Hospital, Singapore
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Chin Meng Khoo
Chin Meng Khoo
Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Department of Medicine, National University Hospital, Singapore
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Department of Medicine, National University Hospital, Singapore
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) syndrome. Patients with PHPT might present with cardinal signs of hypercalcemia with significant involvement from both renal and skeletal system presenting with recurrent nephrolithiasis, fragility fractures, or both ( 2 ). Parathyroidectomy is the
