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Institute of Clinical Endocrinology, Endocrinology Research Center, Moscow, Russian Federation
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Introduction Primary hyperparathyroidism (PHPT) is a common endocrine disorder, predominantly in postmenopausal women ( 1 ). Nevertheless, PHPT can occur at any age, and its incidence increases steadily after age 25 years in both sexes ( 2
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Clinical Research Centre, Medical University of Bialystok, Białystok, Poland
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2020 at the Department of Endocrinology, Diabetology, and Internal Medicine. We examined 25 women with PTC with a median age of 33 (interquartile range: 31–38). Each subject provided a full obstetric history and menstrual cycle details before and after
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-up of CH cases is of particular interest in the last decade. Although unfavorable outcome of untreated CH is well established, recent evidence suggests that many CH children are no longer treated after the age of 3 years ( 4 , 5 , 6 ). To distinguish
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Hospices Civils de Lyon, Hôpital Femme-Mère-Enfant, Service de psychopathologie du développement, Bron, France
Hospices Civils de Lyon, Hôpital Femme-Mère-Enfant, Centre de biologie et pathologie Est, Service d’hormonologie, d’endocrinologie moléculaire et des maladies rares, Bron, France
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Hospices Civils de Lyon, Hôpital Femme-Mère-Enfant, Centre de biologie et pathologie Est, Service d’hormonologie, d’endocrinologie moléculaire et des maladies rares, Bron, France
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Hospices Civils de Lyon, Hôpital Femme-Mère-Enfant, Service Endocrinologie Moléculaire et Maladies Rares, Bron, France
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Hospices Civils de Lyon, Hôpital Femme-Mère-Enfant, Service de chirurgie Uro-viscérale et de Transplantation de l’Enfant, Bron, France
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Hospices Civils de Lyon, Groupement Hospitalier Est, Service d’endocrinologie, Bron, France
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Centre National de Référence Maladies Rares du développement génital du fœtus à l’adulte DEV-GEN, Hospices Civils de Lyon, Bron, France
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Université Claude Bernard, Lyon, France
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Centre National de Référence Maladies Rares du développement génital du fœtus à l’adulte DEV-GEN, Hospices Civils de Lyon, Bron, France
Université Claude Bernard, Lyon, France
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Hospices Civils de Lyon, Hôpital Femme-Mère-Enfant, Service de chirurgie Uro-viscérale et de Transplantation de l’Enfant, Bron, France
Université Claude Bernard, Lyon, France
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Centre National de Référence Maladies Rares du développement génital du fœtus à l’adulte DEV-GEN, Hospices Civils de Lyon, Bron, France
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and age at molecular diagnosis according to the year of birth. Due to an insufficient number of patients, no statistical trend analysis was performed. However, regarding the timing of molecular diagnosis, a statistical comparison was made between two
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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glucuronidation of T due to a homozygous UGT2B17 deletion have altered T clearance, which may consequently influence the age at which boys develop androgen-dependent pubic hair. Figure 1 Predicted probability of age at PH2+ (onset of pubic hair Tanner
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serum TSH of <0.1 μIU/mL. The endpoint of this study was cause-specific survival rate (CSS), and the evaluation items were age at initial operation, sex, histopathology, time of lung metastasis detection, and maximum tumor diameter at the time of lung
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Department of Psychiatry, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan
School of Medicine, Tzu Chi University, Hualien, Taiwan
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eliminated from the case cohort. For each patient in the case cohort, one control subject matched by age, gender, index year, and Charlson Comorbidity Index (CCI) score was identified from the LHID2000 database (control cohort). Individuals diagnosed with
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Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Munich, Germany
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. Nevertheless, blood TL is used as an easily accessible and well-established surrogate tissue for TL in other cells of the entire organism, especially when analyzing systemic effects of chronic diseases ( 6 ). Typically, TL shortens with aging and shorter
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Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Sweden
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patients with APS1. Materials and methods Patients and controls We enrolled 23 patients (19 families) with APS1 [(median age 14 years; range 0.5–30 years); 12 males], diagnosed between 1996 and 2015. The study comprises 11 patients presenting to
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Section of Biostatistics, Department of Public Health, University of Copenhagen, Copenhagen, Denmark
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of which some were prepubertal at last follow-up), the follow-up times were limited (median age at last follow-up 14–19 years), and importantly, none of the studies included semen quality data. Moreover, no previous studies have investigated pubertal