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Marieke Stientje Velema Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands

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Aline de Nooijer Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands

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Ad R M M Hermus Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands

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Henri J L M Timmers Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands

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Jacques W M Lenders Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands
Department of Internal Medicine III, University Hospital Carl Gustav Carus at the Technical University Dresden, Dresden, Germany

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Olga Husson Division of Clinical Studies, Institute of Cancer Research, London, UK

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Jaap Deinum Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands
Department of Internal Medicine III, University Hospital Carl Gustav Carus at the Technical University Dresden, Dresden, Germany

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values ( 5 , 6 ) and improvement in HRQoL after ADX ( 5 ) and during MRA-based treatment ( 6 ). Furthermore, psychological symptoms impairing HRQoL in patients with PA have been reported: occurrence of anxiety disorders and stress is higher than in the

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Kimberly Kuiper Clinical Neurodevelopmental Sciences, Leiden University, Leiden, The Netherlands
Leiden Institute for Brain and Cognition, Leiden, The Netherlands

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Hanna Swaab Clinical Neurodevelopmental Sciences, Leiden University, Leiden, The Netherlands
Leiden Institute for Brain and Cognition, Leiden, The Netherlands

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Nicole Tartaglia eXtraordinarY Kids Clinic, Developmental Pediatrics, Children’s Hospital Colorado, Aurora, Colorado
Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado

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Sophie van Rijn Clinical Neurodevelopmental Sciences, Leiden University, Leiden, The Netherlands
Leiden Institute for Brain and Cognition, Leiden, The Netherlands

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to adequately influence the occurrence and cope with the intensity, duration, and expression of emotions ( 7 ). In this study, physiological arousal (as an indicator of emotional stress response) and behavioral regulation will be evaluated

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Mohammed S Albreiki Department of Biochemistry and Physiology, Centre for Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK

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Benita Middleton Department of Biochemistry and Physiology, Centre for Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK

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Shelagh M Hampton Department of Biochemistry and Physiology, Centre for Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK

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lipase (LPL). A majority of the previous studies investigating the effect of light on hormone and metabolic responses have either been carried out on experimental animals ( 14 ) or under-restricted conditions in humans such as constant routine ( 16

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Gareth Leng Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK

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Zuckerman ( 6 ) cut the neural stalk, and their case rested on results from two of them, two that had come into heat in response to artificial light even though, from their histological evidence, all connections between brain and pituitary had been

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Jesper Krogh Department of Endocrinology & Metabolism, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark

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Peter Plomgaard Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Biochemistry, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark

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Ruth Frikke-Schmidt Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Biochemistry, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark

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Sten Velschow Fluisense ApS, Lillerød, Denmark

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Jesper Johannesen Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
Department of Pediatrics, Copenhagen University Hospital - Herlev & Gentofte, Copenhagen, Denmark

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Linda Maria Hilsted Department of Clinical Biochemistry, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark

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Malene Schrøder Fluisense ApS, Lillerød, Denmark

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Ulla Feldt-Rasmussen Department of Endocrinology & Metabolism, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark

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first sample was 203.8 nmol/L compared to 218.0 nmol/L in the second sample ( P  = 0.64), suggesting a minimal stress response to the insertion of the Fluispotter catheter, which must be considered one of the clinically important exploratory outcomes of

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Arno Téblick Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium

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Lies Langouche Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium

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Greet Van den Berghe Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium

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hallmark of critical illness, is the immediate initiation of multiple physiologic processes in an attempt to rebalance the complex dynamic equilibrium, commonly known as homeostasis. This so-called ‘stress response’ comprises many tightly controlled neural

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D A Dart Cardiff China Medical Research Collaborative, Cardiff University School of Medicine, Cardiff, Wales, UK
Imperial College London, London, UK

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K Ashelford Division of Cancer and Genetics, Wales Gene Park, School of Medicine, Cardiff University, Cardiff, Wales, UK

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W G Jiang Cardiff China Medical Research Collaborative, Cardiff University School of Medicine, Cardiff, Wales, UK

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, to test whether the AR ‘splicing’ event was unique to AR pathway inhibition or was a more general stress response, we subjected LNCaP cells to a variety of cellular stresses including hypoxia (mimicked by CoCl 2 ), DNA damaging stress (by

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Clara Lundetoft Clausen Center of Research & Disruption of Infectious Diseases, Department of Infectious Diseases, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark

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Trine Holm Johannsen Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark

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Niels Erik Skakkebæk Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark

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Hanne Frederiksen Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark

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Anders Juul Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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Thomas Benfield Center of Research & Disruption of Infectious Diseases, Department of Infectious Diseases, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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glucocorticoid treatment has been effective in improving outcomes in patients with hypoxemic COVID-19 ( 9 ). This suggests an inadequate physiological stress response in COVID-19 patients. Our findings do not support the presence of CIRCI at an enzymatic level in

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Xiaohui Weng School of Mechanical and Aerospace Engineering, Jilin University, Changchun, China
Weihai Institute for Bionics, Jilin University, Weihai, China

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Gehong Li School of Mathematics, Jilin University, Changchun, China

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Ziwei Liu Department of endocrinology, Jinshan Branch of Shanghai Sixth People's Hospital, Shanghai, China

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Rui Liu Department of VIP Unit, China-Japan Union Hospital of Jilin University, Changchun, China

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Zhaoyang Liu Digital Intelligent Cockpit Department, Intelligent Connected Vehicle Development Institute, China FAW Group Co LTD, Changchun, China

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Songyang Wang Digital Intelligent Cockpit Department, Intelligent Connected Vehicle Development Institute, China FAW Group Co LTD, Changchun, China

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Shishun Zhao School of Mathematics, Jilin University, Changchun, China

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Xiaotong Ma School of Mathematics, Jilin University, Changchun, China

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Zhiyong Chang Weihai Institute for Bionics, Jilin University, Weihai, China
College of Biological and Agricultural Engineering, Jilin University, Changchun, China
Key Laboratory of Bionic Engineering, Ministry of Education, Jilin University, Changchun, China

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the baseline level before the next set of sampling. Table 1 Summary of the sensor array. Number The gas sensor The response characteristics S1 TGS2612 Butane, methane, propane. S2 TGS2611 Methane, natural

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Sarah Christine Sentis Institute for Endocrinology and Diabetes, Center of Brain, Behavior and Metabolism (CBBM), University of Lübeck, Lübeck, Germany

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Rebecca Oelkrug Institute for Endocrinology and Diabetes, Center of Brain, Behavior and Metabolism (CBBM), University of Lübeck, Lübeck, Germany

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Jens Mittag Institute for Endocrinology and Diabetes, Center of Brain, Behavior and Metabolism (CBBM), University of Lübeck, Lübeck, Germany

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of great relevance in humans, which possess a large surface area that unlike in rodents is only sparsely covered with fur or hair. Therefore, vasodilation is an important response to dissipate excess heat, that is, during physical exercise, and

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