Keina Nishio
Keina Nishio
Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan
Search for other papers by Keina Nishio in
Google Scholar
PubMed
Search for other papers by Keina Nishio in
Google Scholar
PubMed
Akiko Tanabe
Akiko Tanabe
Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan
Search for other papers by Akiko Tanabe in
Google Scholar
PubMed
Search for other papers by Akiko Tanabe in
Google Scholar
PubMed
Risa Maruoka
Risa Maruoka
Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan
Search for other papers by Risa Maruoka in
Google Scholar
PubMed
Search for other papers by Risa Maruoka in
Google Scholar
PubMed
Kiyoko Nakamura
Kiyoko Nakamura
Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan
Search for other papers by Kiyoko Nakamura in
Google Scholar
PubMed
Search for other papers by Kiyoko Nakamura in
Google Scholar
PubMed
Masaaki Takai
Masaaki Takai
Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan
Search for other papers by Masaaki Takai in
Google Scholar
PubMed
Search for other papers by Masaaki Takai in
Google Scholar
PubMed
Tatsuharu Sekijima
Tatsuharu Sekijima
Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan
Search for other papers by Tatsuharu Sekijima in
Google Scholar
PubMed
Search for other papers by Tatsuharu Sekijima in
Google Scholar
PubMed
Satoshi Tunetoh
Satoshi Tunetoh
Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan
Search for other papers by Satoshi Tunetoh in
Google Scholar
PubMed
Search for other papers by Satoshi Tunetoh in
Google Scholar
PubMed
Yoshito Terai
Yoshito Terai
Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan
Search for other papers by Yoshito Terai in
Google Scholar
PubMed
Search for other papers by Yoshito Terai in
Google Scholar
PubMed
Masahide Ohmichi
Masahide Ohmichi
Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan
Search for other papers by Masahide Ohmichi in
Google Scholar
PubMed
Search for other papers by Masahide Ohmichi in
Google Scholar
PubMed
) . Osteoporosis is common in women with breast cancer who receive chemotherapy, hormone therapy, or surgical castration, because these treatments induce bone loss (8) . Atkinson et al . (9) reported that prepubertal children with lymphoblastic leukemia who
Kirsty G Pringle
Kirsty G Pringle
School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia
Hunter Medical Research Institute, New Lambton, Newcastle, New South Wales, Australia
Search for other papers by Kirsty G Pringle in
Google Scholar
PubMed
Hunter Medical Research Institute, New Lambton, Newcastle, New South Wales, Australia
Search for other papers by Kirsty G Pringle in
Google Scholar
PubMed
Sarah J Delforce
Sarah J Delforce
School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia
Hunter Medical Research Institute, New Lambton, Newcastle, New South Wales, Australia
Search for other papers by Sarah J Delforce in
Google Scholar
PubMed
Hunter Medical Research Institute, New Lambton, Newcastle, New South Wales, Australia
Search for other papers by Sarah J Delforce in
Google Scholar
PubMed
Yu Wang
Yu Wang
School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia
Hunter Medical Research Institute, New Lambton, Newcastle, New South Wales, Australia
Search for other papers by Yu Wang in
Google Scholar
PubMed
Hunter Medical Research Institute, New Lambton, Newcastle, New South Wales, Australia
Search for other papers by Yu Wang in
Google Scholar
PubMed
Katie A Ashton
Katie A Ashton
School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia
Hunter Medical Research Institute, New Lambton, Newcastle, New South Wales, Australia
Search for other papers by Katie A Ashton in
Google Scholar
PubMed
Hunter Medical Research Institute, New Lambton, Newcastle, New South Wales, Australia
Search for other papers by Katie A Ashton in
Google Scholar
PubMed
Anthony Proietto
Anthony Proietto
Hunter Centre for Gynaecological Cancer, John Hunter Hospital, Newcastle, New South Wales, Australia
Search for other papers by Anthony Proietto in
Google Scholar
PubMed
Search for other papers by Anthony Proietto in
Google Scholar
PubMed
Geoffrey Otton
Geoffrey Otton
Hunter Centre for Gynaecological Cancer, John Hunter Hospital, Newcastle, New South Wales, Australia
Search for other papers by Geoffrey Otton in
Google Scholar
PubMed
Search for other papers by Geoffrey Otton in
Google Scholar
PubMed
C Caroline Blackwell
C Caroline Blackwell
School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia
Hunter Medical Research Institute, New Lambton, Newcastle, New South Wales, Australia
Search for other papers by C Caroline Blackwell in
Google Scholar
PubMed
Hunter Medical Research Institute, New Lambton, Newcastle, New South Wales, Australia
Search for other papers by C Caroline Blackwell in
Google Scholar
PubMed
Rodney J Scott
Rodney J Scott
School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia
Hunter Medical Research Institute, New Lambton, Newcastle, New South Wales, Australia
Division of Molecular Medicine, Pathology North, Newcastle, New South Wales, Australia
Search for other papers by Rodney J Scott in
Google Scholar
PubMed
Hunter Medical Research Institute, New Lambton, Newcastle, New South Wales, Australia
Division of Molecular Medicine, Pathology North, Newcastle, New South Wales, Australia
Search for other papers by Rodney J Scott in
Google Scholar
PubMed
Eugenie R Lumbers
Eugenie R Lumbers
School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia
Hunter Medical Research Institute, New Lambton, Newcastle, New South Wales, Australia
Search for other papers by Eugenie R Lumbers in
Google Scholar
PubMed
Hunter Medical Research Institute, New Lambton, Newcastle, New South Wales, Australia
Search for other papers by Eugenie R Lumbers in
Google Scholar
PubMed
arm of the RAS has been found in several cancers such as lung, prostate, cervical and breast cancer ( 10 ). Epidemiological evidence also supports the proposal that the RAS is involved in neoplasia. Suppression of the RAS for hypertension treatment
Agnieszka Kosowska
Agnieszka Kosowska
Department of Biochemistry, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland
Search for other papers by Agnieszka Kosowska in
Google Scholar
PubMed
Search for other papers by Agnieszka Kosowska in
Google Scholar
PubMed
Enrique Gallego-Colon
Enrique Gallego-Colon
Department of Biochemistry, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland
Search for other papers by Enrique Gallego-Colon in
Google Scholar
PubMed
Search for other papers by Enrique Gallego-Colon in
Google Scholar
PubMed
Wojciech Garczorz
Wojciech Garczorz
Department of Biochemistry, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland
Search for other papers by Wojciech Garczorz in
Google Scholar
PubMed
Search for other papers by Wojciech Garczorz in
Google Scholar
PubMed
Agnieszka Kłych-Ratuszny
Agnieszka Kłych-Ratuszny
Department of Biochemistry, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland
Search for other papers by Agnieszka Kłych-Ratuszny in
Google Scholar
PubMed
Search for other papers by Agnieszka Kłych-Ratuszny in
Google Scholar
PubMed
Mohammad Reza F Aghdam
Mohammad Reza F Aghdam
Department of Biochemistry, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland
Search for other papers by Mohammad Reza F Aghdam in
Google Scholar
PubMed
Search for other papers by Mohammad Reza F Aghdam in
Google Scholar
PubMed
Michał Woz´niak
Michał Woz´niak
Department of Biochemistry, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland
Search for other papers by Michał Woz´niak in
Google Scholar
PubMed
Search for other papers by Michał Woz´niak in
Google Scholar
PubMed
Andrzej Witek
Andrzej Witek
Department of Gynaecology and Obstetrics, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland
Search for other papers by Andrzej Witek in
Google Scholar
PubMed
Search for other papers by Andrzej Witek in
Google Scholar
PubMed
Agnieszka Wróblewska-Czech
Agnieszka Wróblewska-Czech
Department of Gynaecology and Obstetrics, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland
Search for other papers by Agnieszka Wróblewska-Czech in
Google Scholar
PubMed
Search for other papers by Agnieszka Wróblewska-Czech in
Google Scholar
PubMed
Anna Cygal
Anna Cygal
Department of Gynaecology and Obstetrics, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland
Search for other papers by Anna Cygal in
Google Scholar
PubMed
Search for other papers by Anna Cygal in
Google Scholar
PubMed
Jerzy Wojnar
Jerzy Wojnar
Department of Internal Medicine and Oncological Chemotherapy, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland
Search for other papers by Jerzy Wojnar in
Google Scholar
PubMed
Search for other papers by Jerzy Wojnar in
Google Scholar
PubMed
Tomasz Francuz
Tomasz Francuz
Department of Biochemistry, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland
Search for other papers by Tomasz Francuz in
Google Scholar
PubMed
Search for other papers by Tomasz Francuz in
Google Scholar
PubMed
is yet to be elucidated. Incretins have shown to inhibit growth and enhance apoptosis of cancer cells through inhibition of the PI3K/Akt pathway for some cell lines of breast ( 17 ), colon cancer ( 18 ) and ovarian cancer ( 19 ). Thus, understating of
Marra Jai Aghajani
Marra Jai Aghajani
Ingham Institute for Applied Medical Research, Liverpool, New South Wales, Australia
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
Search for other papers by Marra Jai Aghajani in
Google Scholar
PubMed
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
Search for other papers by Marra Jai Aghajani in
Google Scholar
PubMed
Tao Yang
Tao Yang
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
Saint Vincent’s Clinical School, UNSW Sydney, Sydney, Australia
SydPath, Saint Vincent’s Hospital, Sydney, Australia
Search for other papers by Tao Yang in
Google Scholar
PubMed
Saint Vincent’s Clinical School, UNSW Sydney, Sydney, Australia
SydPath, Saint Vincent’s Hospital, Sydney, Australia
Search for other papers by Tao Yang in
Google Scholar
PubMed
Ulf Schmitz
Ulf Schmitz
Computational BioMedicine Laboratory Centenary Institute, The University of Sydney, Camperdown, New South Wales, Australia
Gene & Stem Cell Therapy Program Centenary Institute, The University of Sydney, Camperdown, New South Wales, Australia
Faculty of Medicine & Health, The University of Sydney, Camperdown, New South Wales, Australia
Search for other papers by Ulf Schmitz in
Google Scholar
PubMed
Gene & Stem Cell Therapy Program Centenary Institute, The University of Sydney, Camperdown, New South Wales, Australia
Faculty of Medicine & Health, The University of Sydney, Camperdown, New South Wales, Australia
Search for other papers by Ulf Schmitz in
Google Scholar
PubMed
Alexander James
Alexander James
Ingham Institute for Applied Medical Research, Liverpool, New South Wales, Australia
Search for other papers by Alexander James in
Google Scholar
PubMed
Search for other papers by Alexander James in
Google Scholar
PubMed
Charles Eugenio McCafferty
Charles Eugenio McCafferty
Ingham Institute for Applied Medical Research, Liverpool, New South Wales, Australia
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
Search for other papers by Charles Eugenio McCafferty in
Google Scholar
PubMed
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
Search for other papers by Charles Eugenio McCafferty in
Google Scholar
PubMed
Paul de Souza
Paul de Souza
Ingham Institute for Applied Medical Research, Liverpool, New South Wales, Australia
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
School of Medicine, University of Wollongong, New South Wales, Australia
Search for other papers by Paul de Souza in
Google Scholar
PubMed
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
School of Medicine, University of Wollongong, New South Wales, Australia
Search for other papers by Paul de Souza in
Google Scholar
PubMed
Navin Niles
Navin Niles
Ingham Institute for Applied Medical Research, Liverpool, New South Wales, Australia
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
Department of Head & Neck Surgery, Liverpool Hospital, Liverpool, New South Wales, Australia
Department of Clinical Medicine, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia
Search for other papers by Navin Niles in
Google Scholar
PubMed
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
Department of Head & Neck Surgery, Liverpool Hospital, Liverpool, New South Wales, Australia
Department of Clinical Medicine, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia
Search for other papers by Navin Niles in
Google Scholar
PubMed
Tara L Roberts
Tara L Roberts
Ingham Institute for Applied Medical Research, Liverpool, New South Wales, Australia
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
South West Sydney Clinical School, UNSW Sydney, Sydney, Australia
Search for other papers by Tara L Roberts in
Google Scholar
PubMed
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
South West Sydney Clinical School, UNSW Sydney, Sydney, Australia
Search for other papers by Tara L Roberts in
Google Scholar
PubMed
-converted OSCC cell lines expressing high levels of PD-L1 at both protein and mRNA levels were capable of inducing T‐cell apoptosis to a greater extent when compared to the original epithelial type tumour cells ( 44 ). In breast cancer cell lines, EMT-mediated PD
Simon Schimmack
Simon Schimmack
European Pancreas Center, Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany
Search for other papers by Simon Schimmack in
Google Scholar
PubMed
Search for other papers by Simon Schimmack in
Google Scholar
PubMed
Yongchao Yang
Yongchao Yang
European Pancreas Center, Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany
Department of General Surgery, Xiangya Hospital, Central South University, Changsha, China
Department of Burns and Plastic Surgery, The Third Xiangya Hospital, Central South University, Changsha, China
Search for other papers by Yongchao Yang in
Google Scholar
PubMed
Department of General Surgery, Xiangya Hospital, Central South University, Changsha, China
Department of Burns and Plastic Surgery, The Third Xiangya Hospital, Central South University, Changsha, China
Search for other papers by Yongchao Yang in
Google Scholar
PubMed
Klaus Felix
Klaus Felix
European Pancreas Center, Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany
Search for other papers by Klaus Felix in
Google Scholar
PubMed
Search for other papers by Klaus Felix in
Google Scholar
PubMed
Markus Herbst
Markus Herbst
European Pancreas Center, Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany
Search for other papers by Markus Herbst in
Google Scholar
PubMed
Search for other papers by Markus Herbst in
Google Scholar
PubMed
Yixiong Li
Yixiong Li
Department of General Surgery, Xiangya Hospital, Central South University, Changsha, China
Search for other papers by Yixiong Li in
Google Scholar
PubMed
Search for other papers by Yixiong Li in
Google Scholar
PubMed
Miriam Schenk
Miriam Schenk
European Pancreas Center, Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany
Search for other papers by Miriam Schenk in
Google Scholar
PubMed
Search for other papers by Miriam Schenk in
Google Scholar
PubMed
Frank Bergmann
Frank Bergmann
Institute of Pathology, Heidelberg University, Heidelberg, Germany
Search for other papers by Frank Bergmann in
Google Scholar
PubMed
Search for other papers by Frank Bergmann in
Google Scholar
PubMed
Thilo Hackert
Thilo Hackert
European Pancreas Center, Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany
Search for other papers by Thilo Hackert in
Google Scholar
PubMed
Search for other papers by Thilo Hackert in
Google Scholar
PubMed
Oliver Strobel
Oliver Strobel
European Pancreas Center, Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany
Search for other papers by Oliver Strobel in
Google Scholar
PubMed
Search for other papers by Oliver Strobel in
Google Scholar
PubMed
been observed in a growing number of human cancers, such as breast cancer, multiple myeloma, head and neck tumors and both ovarian and prostate cancers ( 18 , 19 , 20 , 21 ). Nothing is known about the role of STAT3 in pNEN. CRP and STAT3 may be part
Vita Birzniece
Vita Birzniece
School of Medicine, Western Sydney University, New South Wales, Australia
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Garvan Institute of Medical Research, New South Wales, Australia
School of Medical Sciences, University of New South Wales, New South Wales, Australia
Search for other papers by Vita Birzniece in
Google Scholar
PubMed
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Garvan Institute of Medical Research, New South Wales, Australia
School of Medical Sciences, University of New South Wales, New South Wales, Australia
Search for other papers by Vita Birzniece in
Google Scholar
PubMed
Teresa Lam
Teresa Lam
School of Medicine, Western Sydney University, New South Wales, Australia
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Department of Diabetes and Endocrinology, Westmead Hospital, New South Wales, Australia
Search for other papers by Teresa Lam in
Google Scholar
PubMed
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Department of Diabetes and Endocrinology, Westmead Hospital, New South Wales, Australia
Search for other papers by Teresa Lam in
Google Scholar
PubMed
Mark McLean
Mark McLean
School of Medicine, Western Sydney University, New South Wales, Australia
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Search for other papers by Mark McLean in
Google Scholar
PubMed
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Search for other papers by Mark McLean in
Google Scholar
PubMed
Navneeta Reddy
Navneeta Reddy
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Search for other papers by Navneeta Reddy in
Google Scholar
PubMed
Search for other papers by Navneeta Reddy in
Google Scholar
PubMed
Haleh Shahidipour
Haleh Shahidipour
School of Medicine, Western Sydney University, New South Wales, Australia
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Search for other papers by Haleh Shahidipour in
Google Scholar
PubMed
Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
Search for other papers by Haleh Shahidipour in
Google Scholar
PubMed
Amy Hayden
Amy Hayden
School of Medicine, Western Sydney University, New South Wales, Australia
Faculty of Medicine, Health and Human Sciences, Macquarie University, New South Wales, Australia
Crown Princess Mary Cancer Centre, Westmead Hospital, New South Wales, Australia
Search for other papers by Amy Hayden in
Google Scholar
PubMed
Faculty of Medicine, Health and Human Sciences, Macquarie University, New South Wales, Australia
Crown Princess Mary Cancer Centre, Westmead Hospital, New South Wales, Australia
Search for other papers by Amy Hayden in
Google Scholar
PubMed
Howard Gurney
Howard Gurney
Crown Princess Mary Cancer Centre, Westmead Hospital, New South Wales, Australia
Search for other papers by Howard Gurney in
Google Scholar
PubMed
Search for other papers by Howard Gurney in
Google Scholar
PubMed
Glenn Stone
Glenn Stone
School of Computing, Engineering and Mathematics, Western Sydney University, New South Wales, Australia
Search for other papers by Glenn Stone in
Google Scholar
PubMed
Search for other papers by Glenn Stone in
Google Scholar
PubMed
Rikke Hjortebjerg
Rikke Hjortebjerg
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
Steno Diabetes Center Odense, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
Search for other papers by Rikke Hjortebjerg in
Google Scholar
PubMed
Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
Steno Diabetes Center Odense, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
Search for other papers by Rikke Hjortebjerg in
Google Scholar
PubMed
Jan Frystyk
Jan Frystyk
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
Search for other papers by Jan Frystyk in
Google Scholar
PubMed
Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
Search for other papers by Jan Frystyk in
Google Scholar
PubMed
vitro studies in other cancer types have demonstrated high levels of IGFBP-3 in cancer cells, with IGFBP-3 stimulating breast cancer growth and being a poor prognostic marker for breast cancer patients ( 67 , 68 , 69 , 70 ). Thus, it is difficult to
Lukas Ochsner Ridder
Lukas Ochsner Ridder
Department of Endocrinology and Internal Medicine and Medical Research Laboratories, Aarhus University Hospital, Aarhus, Denmark
Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
Search for other papers by Lukas Ochsner Ridder in
Google Scholar
PubMed
Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
Search for other papers by Lukas Ochsner Ridder in
Google Scholar
PubMed
Agnethe Berglund
Agnethe Berglund
Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Clinical Genetics and Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
Search for other papers by Agnethe Berglund in
Google Scholar
PubMed
Department of Clinical Genetics and Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
Search for other papers by Agnethe Berglund in
Google Scholar
PubMed
Kirstine Stochholm
Kirstine Stochholm
Department of Endocrinology and Internal Medicine and Medical Research Laboratories, Aarhus University Hospital, Aarhus, Denmark
Search for other papers by Kirstine Stochholm in
Google Scholar
PubMed
Search for other papers by Kirstine Stochholm in
Google Scholar
PubMed
Simon Chang
Simon Chang
Department of Endocrinology and Internal Medicine and Medical Research Laboratories, Aarhus University Hospital, Aarhus, Denmark
Unit for Thrombosis Research, Hospital of South West Jutland and University of Southern Denmark, Esbjerg, Denmark
Search for other papers by Simon Chang in
Google Scholar
PubMed
Unit for Thrombosis Research, Hospital of South West Jutland and University of Southern Denmark, Esbjerg, Denmark
Search for other papers by Simon Chang in
Google Scholar
PubMed
Claus H Gravholt
Claus H Gravholt
Department of Endocrinology and Internal Medicine and Medical Research Laboratories, Aarhus University Hospital, Aarhus, Denmark
Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
Unit for Thrombosis Research, Hospital of South West Jutland and University of Southern Denmark, Esbjerg, Denmark
Search for other papers by Claus H Gravholt in
Google Scholar
PubMed
Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
Unit for Thrombosis Research, Hospital of South West Jutland and University of Southern Denmark, Esbjerg, Denmark
Search for other papers by Claus H Gravholt in
Google Scholar
PubMed
germ-cell neoplasia has not been observed more frequently in KS, only extra-gonadal GCTs derived from somatic cells are more frequent in KS ( 26 ). Based on KS prevalence among breast cancer patients, it is estimated that KS patients have a 50-fold
J Brossaud
J Brossaud
Université de Bordeaux, Nutrition et Neurobiologie Intégrée, Bordeaux, France
Department of Nuclear Medicine, CHU de Bordeaux, Pessac, France
INRA, Nutrition et Neurobiologie Intégrée, UMR1286, Bordeaux, France
Search for other papers by J Brossaud in
Google Scholar
PubMed
Department of Nuclear Medicine, CHU de Bordeaux, Pessac, France
INRA, Nutrition et Neurobiologie Intégrée, UMR1286, Bordeaux, France
Search for other papers by J Brossaud in
Google Scholar
PubMed
V Pallet
V Pallet
Université de Bordeaux, Nutrition et Neurobiologie Intégrée, Bordeaux, France
INRA, Nutrition et Neurobiologie Intégrée, UMR1286, Bordeaux, France
Search for other papers by V Pallet in
Google Scholar
PubMed
INRA, Nutrition et Neurobiologie Intégrée, UMR1286, Bordeaux, France
Search for other papers by V Pallet in
Google Scholar
PubMed
J-B Corcuff
J-B Corcuff
Université de Bordeaux, Nutrition et Neurobiologie Intégrée, Bordeaux, France
Department of Nuclear Medicine, CHU de Bordeaux, Pessac, France
INRA, Nutrition et Neurobiologie Intégrée, UMR1286, Bordeaux, France
Search for other papers by J-B Corcuff in
Google Scholar
PubMed
Department of Nuclear Medicine, CHU de Bordeaux, Pessac, France
INRA, Nutrition et Neurobiologie Intégrée, UMR1286, Bordeaux, France
Search for other papers by J-B Corcuff in
Google Scholar
PubMed
). Unfortunately, different studies did not report a clear usefulness for such a treatment in thyroid cancer ( 49 ). Though, for a similar expected action on NIS, RA is under consideration for the treatment of breast cancer ( 50 ). RA can also modulate the
Kjell Oberg
Kjell Oberg
Uppsala University, Uppsala, Sweden
Search for other papers by Kjell Oberg in
Google Scholar
PubMed
Search for other papers by Kjell Oberg in
Google Scholar
PubMed
Eric Krenning
Eric Krenning
Erasmus Medical Center, Rotterdam, Netherlands
Search for other papers by Eric Krenning in
Google Scholar
PubMed
Search for other papers by Eric Krenning in
Google Scholar
PubMed
Anders Sundin
Anders Sundin
Uppsala University, Uppsala, Sweden
Search for other papers by Anders Sundin in
Google Scholar
PubMed
Search for other papers by Anders Sundin in
Google Scholar
PubMed
Lisa Bodei
Lisa Bodei
Memorial Sloan Kettering Cancer Center, New York, New York, USA
Search for other papers by Lisa Bodei in
Google Scholar
PubMed
Search for other papers by Lisa Bodei in
Google Scholar
PubMed
Mark Kidd
Mark Kidd
Wren Laboratories, Branford, Connecticut, USA
Search for other papers by Mark Kidd in
Google Scholar
PubMed
Search for other papers by Mark Kidd in
Google Scholar
PubMed
Margot Tesselaar
Margot Tesselaar
Netherlands Cancer Institute, Amsterdam, Netherlands
Search for other papers by Margot Tesselaar in
Google Scholar
PubMed
Search for other papers by Margot Tesselaar in
Google Scholar
PubMed
Valentina Ambrosini
Valentina Ambrosini
University of Bologna, Bologna, Italy
Search for other papers by Valentina Ambrosini in
Google Scholar
PubMed
Search for other papers by Valentina Ambrosini in
Google Scholar
PubMed
Richard P Baum
Richard P Baum
Zentralklinik Bad Berka, Bad Berka, Germany
Search for other papers by Richard P Baum in
Google Scholar
PubMed
Search for other papers by Richard P Baum in
Google Scholar
PubMed
Matthew Kulke
Matthew Kulke
Dana Farber Cancer Institute, Boston, Massachusetts, USA
Search for other papers by Matthew Kulke in
Google Scholar
PubMed
Search for other papers by Matthew Kulke in
Google Scholar
PubMed
Marianne Pavel
Marianne Pavel
Charite Hospital, Berlin, Germany
Search for other papers by Marianne Pavel in
Google Scholar
PubMed
Search for other papers by Marianne Pavel in
Google Scholar
PubMed
Jaroslaw Cwikla
Jaroslaw Cwikla
University of Warmia and Mazury, Olsztyn, Poland
Search for other papers by Jaroslaw Cwikla in
Google Scholar
PubMed
Search for other papers by Jaroslaw Cwikla in
Google Scholar
PubMed
Ignat Drozdov
Ignat Drozdov
Wren Laboratories, Branford, Connecticut, USA
Search for other papers by Ignat Drozdov in
Google Scholar
PubMed
Search for other papers by Ignat Drozdov in
Google Scholar
PubMed
Massimo Falconi
Massimo Falconi
Ospedale San Raffaele, Milan, Italy
Search for other papers by Massimo Falconi in
Google Scholar
PubMed
Search for other papers by Massimo Falconi in
Google Scholar
PubMed
Nicola Fazio
Nicola Fazio
IEO (European Institute of Oncology), Milan, Italy
Search for other papers by Nicola Fazio in
Google Scholar
PubMed
Search for other papers by Nicola Fazio in
Google Scholar
PubMed
Andrea Frilling
Andrea Frilling
Imperial College London, London, UK
Search for other papers by Andrea Frilling in
Google Scholar
PubMed
Search for other papers by Andrea Frilling in
Google Scholar
PubMed
Robert Jensen
Robert Jensen
National Institutes of Health, Bethesda, Maryland, USA
Search for other papers by Robert Jensen in
Google Scholar
PubMed
Search for other papers by Robert Jensen in
Google Scholar
PubMed
Klaus Koopmans
Klaus Koopmans
Martini Ziekenhuis, Groningen, Netherlands
Search for other papers by Klaus Koopmans in
Google Scholar
PubMed
Search for other papers by Klaus Koopmans in
Google Scholar
PubMed
Tiny Korse
Tiny Korse
Netherlands Cancer Institute, Amsterdam, Netherlands
Search for other papers by Tiny Korse in
Google Scholar
PubMed
Search for other papers by Tiny Korse in
Google Scholar
PubMed
Dik Kwekkeboom
Dik Kwekkeboom
Erasmus Medical Center, Rotterdam, Netherlands
Search for other papers by Dik Kwekkeboom in
Google Scholar
PubMed
Search for other papers by Dik Kwekkeboom in
Google Scholar
PubMed
Helmut Maecke
Helmut Maecke
University Hospital Freiburg, Freiburg, Germany
Search for other papers by Helmut Maecke in
Google Scholar
PubMed
Search for other papers by Helmut Maecke in
Google Scholar
PubMed
Giovanni Paganelli
Giovanni Paganelli
Instituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Meldola, Italy
Search for other papers by Giovanni Paganelli in
Google Scholar
PubMed
Search for other papers by Giovanni Paganelli in
Google Scholar
PubMed
Ramon Salazar
Ramon Salazar
Instituto Catala d’Oncologia, Barcelona, Spain
Search for other papers by Ramon Salazar in
Google Scholar
PubMed
Search for other papers by Ramon Salazar in
Google Scholar
PubMed
Stefano Severi
Stefano Severi
Instituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Meldola, Italy
Search for other papers by Stefano Severi in
Google Scholar
PubMed
Search for other papers by Stefano Severi in
Google Scholar
PubMed
Jonathan Strosberg
Jonathan Strosberg
H. Lee Moffitt Cancer Center, Tampa, Florida, USA
Search for other papers by Jonathan Strosberg in
Google Scholar
PubMed
Search for other papers by Jonathan Strosberg in
Google Scholar
PubMed
Vikas Prasad
Vikas Prasad
Charite Hospital, Berlin, Germany
Search for other papers by Vikas Prasad in
Google Scholar
PubMed
Search for other papers by Vikas Prasad in
Google Scholar
PubMed
Aldo Scarpa
Aldo Scarpa
University of Verona, Verona, Italy
Search for other papers by Aldo Scarpa in
Google Scholar
PubMed
Search for other papers by Aldo Scarpa in
Google Scholar
PubMed
Ashley Grossman
Ashley Grossman
Univeristy of Oxford, Oxford, UK
Search for other papers by Ashley Grossman in
Google Scholar
PubMed
Search for other papers by Ashley Grossman in
Google Scholar
PubMed
Annemeik Walenkamp
Annemeik Walenkamp
University of Groningen, Groningen, Netherlands
Search for other papers by Annemeik Walenkamp in
Google Scholar
PubMed
Search for other papers by Annemeik Walenkamp in
Google Scholar
PubMed
Mauro Cives
Mauro Cives
H. Lee Moffitt Cancer Center, Tampa, Florida, USA
Search for other papers by Mauro Cives in
Google Scholar
PubMed
Search for other papers by Mauro Cives in
Google Scholar
PubMed
Irene Virgolini
Irene Virgolini
Medical University Innsbruck, Innsbruck, Austria
Search for other papers by Irene Virgolini in
Google Scholar
PubMed
Search for other papers by Irene Virgolini in
Google Scholar
PubMed
Andreas Kjaer
Andreas Kjaer
Copenhagen University, Copenhagen, Denmark
Search for other papers by Andreas Kjaer in
Google Scholar
PubMed
Search for other papers by Andreas Kjaer in
Google Scholar
PubMed
Irvin M Modlin
Irvin M Modlin
Yale University, New Haven, Connecticut, USA
Search for other papers by Irvin M Modlin in
Google Scholar
PubMed
Search for other papers by Irvin M Modlin in
Google Scholar
PubMed
biology interfaced with mathematical algorithms to facilitate interpretation have been developed for breast, lung and hematological malignancies ( 57 , 58 , 59 , 60 ). Therefore, a key unmet need that remains is the development of a clinically
K L Gatford
K L Gatford
School of Paediatrics and Reproductive Health, Robinson Research Institute, University of Adelaide, Adelaide, South Australia 5005, Australia
Search for other papers by K L Gatford in
Google Scholar
PubMed
Search for other papers by K L Gatford in
Google Scholar
PubMed
G K Heinemann
G K Heinemann
School of Paediatrics and Reproductive Health, Robinson Research Institute, University of Adelaide, Adelaide, South Australia 5005, Australia
Search for other papers by G K Heinemann in
Google Scholar
PubMed
Search for other papers by G K Heinemann in
Google Scholar
PubMed
S D Thompson
S D Thompson
School of Paediatrics and Reproductive Health, Robinson Research Institute, University of Adelaide, Adelaide, South Australia 5005, Australia
Search for other papers by S D Thompson in
Google Scholar
PubMed
Search for other papers by S D Thompson in
Google Scholar
PubMed
J V Zhang
J V Zhang
School of Paediatrics and Reproductive Health, Robinson Research Institute, University of Adelaide, Adelaide, South Australia 5005, Australia
Search for other papers by J V Zhang in
Google Scholar
PubMed
Search for other papers by J V Zhang in
Google Scholar
PubMed
S Buckberry
S Buckberry
School of Paediatrics and Reproductive Health, Robinson Research Institute, University of Adelaide, Adelaide, South Australia 5005, Australia
Search for other papers by S Buckberry in
Google Scholar
PubMed
Search for other papers by S Buckberry in
Google Scholar
PubMed
J A Owens
J A Owens
School of Paediatrics and Reproductive Health, Robinson Research Institute, University of Adelaide, Adelaide, South Australia 5005, Australia
Search for other papers by J A Owens in
Google Scholar
PubMed
Search for other papers by J A Owens in
Google Scholar
PubMed
G A Dekker
G A Dekker
School of Paediatrics and Reproductive Health, Robinson Research Institute, University of Adelaide, Adelaide, South Australia 5005, Australia
Search for other papers by G A Dekker in
Google Scholar
PubMed
Search for other papers by G A Dekker in
Google Scholar
PubMed
C T Roberts
C T Roberts
School of Paediatrics and Reproductive Health, Robinson Research Institute, University of Adelaide, Adelaide, South Australia 5005, Australia
Search for other papers by C T Roberts in
Google Scholar
PubMed
Search for other papers by C T Roberts in
Google Scholar
PubMed
on behalf of the SCOPE Consortium
on behalf of the SCOPE Consortium
School of Paediatrics and Reproductive Health, Robinson Research Institute, University of Adelaide, Adelaide, South Australia 5005, Australia
Search for other papers by on behalf of the SCOPE Consortium in
Google Scholar
PubMed
Search for other papers by on behalf of the SCOPE Consortium in
Google Scholar
PubMed
concentrations in other populations (23, 24, 25) . Consistent with a positive effect of the IGF1 rs7965399 C allele on IGF1, this allele was also associated with a trend towards higher IGF1 concentration in breast tumours (26) . Circulating IGF1 is also
