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Yao Su Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Li Chen Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Dong-Yao Zhang Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Xu-Pei Gan Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Yan-Nan Cao Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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De-Cui Cheng Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Wen-Yu Liu Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Fei-Fei Li Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Xian-Ming Xu Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Hong-Kun Wang Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Introduction Gestational diabetes mellitus (GDM) is one of the most common complications during pregnancy, and the incidence rate is increasing every year and is currently approximately 17.5% in China ( 1 ). GDM is harmful to the long- and

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Kjersti S Bakken Women’s Clinic, Innlandet Hospital Trust, Lillehammer, Norway
Center for International Health, University of Bergen, Bergen, Norway

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Kristina Randjelovic Nermo Center for International Health, University of Bergen, Bergen, Norway
Department of Microbiology, Innlandet Hospital Trust, Lillehammer, Norway

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Bjørn Gunnar Nedrebø Department of Medicine, Haugesund Hospital, Haugesund, Norway
Department of Clinical Science, University of Bergen, Bergen, Norway

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Tim I M Korevaar Academic Center for Thyroid Diseases, Erasmus University Medical Center, Rotterdam, the Netherlands

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Tor A Strand Center for International Health, University of Bergen, Bergen, Norway
Department of Research, Innlandet Hospital Trust, Lillehammer, Norway

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Background Optimal thyroid function during pregnancy is essential for both the mother and the developing fetus since thyroid hormones regulate the metabolism, growth, maintenance of pregnancy and development of the fetal CNS ( 1 ). During

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Irasema Mendieta Facultad de Química, Universidad Autónoma de Querétaro, Querétaro, Mexico

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Rosa Elvira Nuñez-Anita Facultad de Medicina Veterinaria y Zootecnia, Universidad Michoacana de San Nicolás Hidalgo, Morelia, Michoacán, Mexico

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Gilberto Pérez-Sánchez Departmento de Psicoimunología, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Ciudad de México, Mexico

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Lenin Pavón Departmento de Psicoimunología, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Ciudad de México, Mexico

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Alfredo Rodríguez-Cruz Facultad de Química, Universidad Autónoma de Querétaro, Querétaro, Mexico

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Guadalupe García-Alcocer Facultad de Química, Universidad Autónoma de Querétaro, Querétaro, Mexico

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Laura Cristina Berumen Facultad de Química, Universidad Autónoma de Querétaro, Querétaro, Mexico

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Introduction Lung cancer is a leading cause of death due to cancer in both sexes worldwide ( 1 , 2 ). A primary concern of this disease is the neuroendocrine phenotype linked to decreased survival and increased peripheral tumour cells, drug

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Andrew R Dismukes Department of Human Development and Family Studies, Iowa State University, Ames, Iowa, USA
Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA

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Vanessa J Meyer Department of Human Development and Family Studies, Iowa State University, Ames, Iowa, USA
Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA

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Elizabeth A Shirtcliff Department of Human Development and Family Studies, Iowa State University, Ames, Iowa, USA

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Katherine P Theall Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA

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Kyle C Esteves Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA

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Stacy S Drury Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA

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Introduction Dehydroepiandrosterone (DHEA) is a steroid hormone that is sometimes called the ‘anti-aging hormone’ because of ts protective effects on memory, neuronal growth, and neuronal activity ( 1 ). DHEA is produced both centrally, as a

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June Young Choi Department of Surgery, Seoul National University Bundang Hospital, Seongnam-si, Korea

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Jin Wook Yi Department of Surgery, Seoul National University Hospital and College of Medicine, Seoul, Korea

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Jun Hyup Lee Department of Surgery, Seoul National University Hospital and College of Medicine, Seoul, Korea

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Ra-Yeong Song Department of Surgery, Seoul National University Hospital and College of Medicine, Seoul, Korea

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Hyeongwon Yu Department of Surgery, Seoul National University Bundang Hospital, Seongnam-si, Korea

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Hyungju Kwon Department of Surgery, Seoul National University Hospital and College of Medicine, Seoul, Korea

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Young Jun Chai Department of Surgery, Seoul National University Boramae Hospital, Seoul, Korea

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Su-jin Kim Department of Surgery, Seoul National University Hospital and College of Medicine, Seoul, Korea

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Kyu Eun Lee Department of Surgery, Seoul National University Hospital and College of Medicine, Seoul, Korea

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controlling breast cancer cell proliferation . Lancet 1989 1 188 – 191 . ( doi:10.1016/S0140-6736(89)91204-X ) 26 Haussler MR Whitfield GK Haussler CA Hsieh JC Thompson PD Selznick SH Dominguez CE Jurutka PW. The

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Yuan Zhou Department of Endocrinology and Metabology, The First Affiliated Hospital of Shandong First Medical University, Ji-nan, China
Laboratory of Endocrinology, Medical Research Center, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, Ji-nan, China

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ShengNan Wang Department of Endocrinology and Metabology, The First Affiliated Hospital of Shandong First Medical University, Ji-nan, China
Laboratory of Endocrinology, Medical Research Center, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, Ji-nan, China

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Jing Wu Department of Endocrinology and Metabology, The First Affiliated Hospital of Shandong First Medical University, Ji-nan, China
Laboratory of Endocrinology, Medical Research Center, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, Ji-nan, China

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JianJun Dong Department of Endocrinology, Qilu Hospital of Shandong University, Ji-nan, China

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Lin Liao Department of Endocrinology and Metabology, The First Affiliated Hospital of Shandong First Medical University, Ji-nan, China
Department of Endocrinology and Metabology, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Ji-nan, China

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Introduction Currently, diabetes has become a public health problem that has garnered worldwide attention. In addition to the well-known type 1 diabetes (T1D) and type 2 diabetes (T2D), a growing number of special types of diabetes and their

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Adrian F Daly Department of Endocrinology, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium

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David A Cano Unidad de Gestión de Endocrinología y Nutrición, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain

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Eva Venegas-Moreno Unidad de Gestión de Endocrinología y Nutrición, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain

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Patrick Petrossians Department of Endocrinology, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium

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Elena Dios Unidad de Gestión de Endocrinología y Nutrición, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain

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Emilie Castermans Department of Human Genetics, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium

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Alvaro Flores-Martínez Unidad de Gestión de Endocrinología y Nutrición, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain

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Vincent Bours Department of Human Genetics, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium

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Albert Beckers Department of Endocrinology, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium

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Alfonso Soto-Moreno Unidad de Gestión de Endocrinología y Nutrición, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain

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MEN1 status 1 FIPA (2-member homogeneous prolactinoma) 60 15 MacroAd No No WT; MLPA normal WT; MLPA normal 2 FIPA (2-member homogeneous prolactinoma) 13 27 MacroAd No no p.D172D; polymorphism; MLPA normal

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Fernando Aprile-Garcia Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina
Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina

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María Antunica-Noguerol Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina
Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina

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Maia Ludmila Budziñski Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina

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Ana C Liberman Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina

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Eduardo Arzt Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina
Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina

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(ADP-ribose) polymerase-1 in CNS disease . Neuroscience 2007 145 1267 – 1272 . ( doi:10.1016/j.neuroscience.2006.09.034 ). 112 Eliasson MJ Sampei K Mandir AS Hurn PD Traystman RJ Bao J Pieper A Wang ZQ Dawson TM Snyder SH . Poly(ADP-ribose) polymerase gene disruption

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Wang Chengji College of Physical Education, Chaohu University, Anhui Province, China

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Fan Xianjin College of Physical Education, Chaohu University, Anhui Province, China

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, report development and interpretation of study findings. Fan Xianjin participated in writing the report. References 1 Willi C Bodenmann P Ghali WA Faris PD Cornuz J . Active smoking and the risk

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E T Aristizabal Prada Department of Internal Medicine IV, Campus Grosshadern, University-Hospital, Ludwig-Maximilians-University of Munich, Munich, Germany

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C J Auernhammer Department of Internal Medicine IV, Campus Grosshadern, University-Hospital, Ludwig-Maximilians-University of Munich, Munich, Germany

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–Raf–MEK–ERK pathway were obtained with the PI3K inhibitor BKM120 and the PI3K/mTOR inhibitor BEZ235 in combination with the MEK inhibitor PD0325901 in human neuroendocrine BON1, H727 and QGP1 cells in vitro and a BON1 xenograft model in vivo ( 73 ) and with the

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