Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina
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Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina
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Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina
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genes such as inflammatory cytokines (e.g. IL1β, IL6, and TNFα), cytokine receptors, adhesion molecules (e.g. ICAM1, VCAM, and E-selectin), and chemotactic proteins and thus are indispensable for the propagation of inflammation (29, 33) . All of these
Department of Surgery, The University of Melbourne, Parkville, Victoria, Australia
Department of Urology, Royal Melbourne Hospital, Parkville, Victoria, Australia
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Department of Urology, Royal Melbourne Hospital, Parkville, Victoria, Australia
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Department of Urology, Royal Melbourne Hospital, Parkville, Victoria, Australia
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Australian Prostate Cancer Research Centre Epworth, Richmond, Victoria, Australia
Ontario Institute for Cancer Research, Toronto, Canada
Princess Margaret Cancer Centre, University Health Network, Toronto, Canada
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Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia
Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia
Department of Mathematics and Statistics, University of Melbourne, Melbourne, Victoria, Australia
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Department of Urology, Royal Melbourne Hospital, Parkville, Victoria, Australia
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Department of Urology, Royal Melbourne Hospital, Parkville, Victoria, Australia
Department of Urology, Frankston Hospital, Frankston, Victoria, Australia
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60°C for 20 s. Expression levels of target genes were normalised to the geometric mean of GAPDH (Hs00266705_g1, Applied Biosystems), TBP (Hs00427621_m1, Applied Biosystems) and POLR2A (Hs00427621_m1, Applied Biosystems) using the formula 2 −ΔC
Institution of Cardiovascular Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Institution of Cardiovascular Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Institution of Cardiovascular Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Institution of Cardiovascular Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Institution of Cardiovascular Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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circumference (WC) was adopted as a factor that is more suitable for the Chinese population. Criteria of MetS were as follows ( 15 ): (i) Central obesity: WC ≥ 90 cm in men or ≥ 80 cm in women; (ii) TG ≥ 1.7 mmol/L or treatment of this lipid abnormality; (iii
Center for Primary Health Care Research, Lund University, Malmö, Sweden
GeneWerk GmbH, Heidelberg, Germany
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Departments of Family Medicine and Community Health, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Center for Community-based Healthcare Research and Education (CoHRE), Department of Functional Pathology, School of Medicine, Shimane University, Shimane, Japan
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Departments of Family Medicine and Community Health, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Center for Community-based Healthcare Research and Education (CoHRE), Department of Functional Pathology, School of Medicine, Shimane University, Shimane, Japan
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Center for Primary Health Care Research, Lund University, Malmö, Sweden
Hopp Children’s Cancer Center (KiTZ), Heidelberg, Germany
Division of Pediatric Neurooncology, German Cancer Research Centre (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany
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Center for Primary Health Care Research, Lund University, Malmö, Sweden
Division of Cancer Epidemiology, German Cancer Research Centre (DKFZ), Heidelberg, Germany
Faculty of Medicine and Biomedical Center in Pilsen, Charles University in Prague, Pilsen, Czech Republic
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autoantibodies ( 4 , 5 ). AD is part of the rare juvenile APS-1, which is usually diagnosed before age 15 years and is caused by recessive mutations in the autoimmune regulatory gene (AIRE) ( 4 , 5 ). The more common adult-onset APS-2 is defined through co
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levels and HbA1c ( 11 , 13 ). Hypoandrogenism in men and hyperandrogenism in women (e.g., the polycystic ovary syndrome) have been linked to insulin resistance and the metabolic syndrome ( 13 , 14 ). In one report, SHBG levels predicted the development
Department of Surgery (Section for Upper Gastrointestinal and Hepatico-Pancreatico-Biliary Surgery), Aarhus University Hospital, Aarhus N, Denmark
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Introduction Iodothyronines secreted from the thyroid gland – in particular triiodothyronine (T3) and thyroxine (T4) – are vital to the regulation of genes associated with cell metabolism and cell growth ( 1 ). Hyperthyroidism and
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/or KEAP1 genes and retained pRB protein expression (non-small-cell lung carcinoma (NSCLC)-like) ( 7 , 8 ). In addition, a LCNEC subtype with lower Ki-67 PI was identified having a MEN1 mutation and, more recently, a study showed overlapping molecular
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DZHK (German Centre for Cardiovascular Research), Greifswald, Germany
DZD (German Center for Diabetes Research), Greifswald, Germany
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Institute and Policlinic for Radiology and Interventional Radiology, University Hospital, Carl-Gustav-Carus University Dresden, Dresden, Germany
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DZHK (German Centre for Cardiovascular Research), Greifswald, Germany
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DZHK (German Centre for Cardiovascular Research), Greifswald, Germany
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DZHK (German Centre for Cardiovascular Research), Greifswald, Germany
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more often never smokers and consumed less alcohol than men. With respect to metabolic syndrome-related parameters, women showed lower concentrations of total triglycerides, HbA1c, glucose, blood pressure as well as a smaller waist circumference and a
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for Sex; confirmed by bootstrap 95% CI: 0.01–0.15). Women with DRD2/ANKK1 gene A2A2 genotype and men with DRD2/ANKK1 A1 allele had higher odds to survive to older age (F(1,157) = 4.37, P = 0.038; η 2 = 0.03; confirmed by bootstrap 95% CI: 0
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study participants were women ( Table 1 ). The mean (± s.d. ) age of the main analysis population was 59.7 ± 7.8 years. The median TSH value in this main analysis population was 1.26 mIU/L (interquartile range: 0.83–1.84). Men and women did not differ