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Yiyan Wang Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China

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Yaoyao Dong Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China

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Yinghui Fang Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China

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Yao Lv Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China

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Qiqi Zhu Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China

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Xiaoheng Li Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China

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Qingquan Lian Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China

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Ren-Shan Ge Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China

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, inhibition of HSD11B2 activity by a potent inhibitor carbenoxolone in cultured trophoblast cells stimulated secretion of the human chorionic gonadotropin and caused a rapid differentiation of cytotrophoblasts into syncytial trophoblasts ( 12 ). Therefore, HSD

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0288
Volume/Issue:
Volume 8: Issue 7
Open access
Masafumi Tetsuka Department of Life and Food Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan

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Misato Tanakadate Department of Life and Food Science, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan

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regulated; cumulus cells only express HSD11B1, and its expression and activity increase in mature COCs, whereas oocytes only express HSD11B2, and its expression and activity remain unchanged irrespective of oocyte maturity ( 13 ). These results indicate that

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0188
Volume/Issue:
Volume 8: Issue 7
Open access
Masatada Watanabe Laboratory of Tissue Regeneration, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Shinagawa, Tokyo, Japan

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Shuji Ohno Division of Research for Pharmacy Students Education, Hoshi University, Shinagawa, Tokyo, Japan

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Hiroshi Wachi Laboratory of Tissue Regeneration, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Shinagawa, Tokyo, Japan

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arrow indicates the position of promoter I.4. (B) RT-PCR analysis of the expression of β-adrenergic receptors in THP-1 cells. Expression of gene transcripts of the β1-adrenergic receptor (β1-AR) and the β2-AR were examined by RT-PCR using specific

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-16-0099
Volume/Issue:
Volume 6: Issue 2
Open access
Tian Zhou School of Clinical Medicine, GuiZhou Medical University, Guiyang, Guizhou, China
Department of Breast Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China

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Dai-wei Zhao School of Clinical Medicine, GuiZhou Medical University, Guiyang, Guizhou, China
Department of Surgery, Second People's Hospital of Guizhou Province, Guiyang, Guizhou, China

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Ning Ma School of Clinical Medicine, GuiZhou Medical University, Guiyang, Guizhou, China

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Xue-ying Zhu School of Clinical Medicine, GuiZhou Medical University, Guiyang, Guizhou, China

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Xing-hong Chen Department of Surgery, Second People's Hospital of Guizhou Province, Guiyang, Guizhou, China

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Xue Luo Department of Breast Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China

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Song Chen School of Clinical Medicine, GuiZhou Medical University, Guiyang, Guizhou, China

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Qing-jun Gao Department of Thyroid Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China

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T cell receptor signaling pathway. Figure 2 (A) The upregulated and downregulated genes screened by DEGs. (B) The heatmap for screening the upregulated and downregulated genes. (C) Main upregulated pathways in DEG gene enrichment by KEGG

Article Type:
Research Article
Collections:
Thyroid
DOI:
https://doi.org/10.1530/EC-22-0390
Volume/Issue:
Volume 12: Issue 4
Open access
Bo Zhu Department of Obstetrics and Gynecology, Assisted Reproduction Unit, Sir Run Run ShawHospital, Zhejiang University School of Medicine Key Laboratory of Reproductive Dysfunction Management of Zhejiang Province, Hangzhou, Zhejiang, China
Department of Gynecology and Obstetrics, Wenzhou People’s Hospital, Wenzhou Women and Children Health, Wenzhou, Zhejiang, China

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Yumei Chen Department of Gynecology and Obstetrics, Wenzhou People’s Hospital, Wenzhou Women and Children Health, Wenzhou, Zhejiang, China

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Fang Xu Department of Gynecology and Obstetrics, Wenzhou People’s Hospital, Wenzhou Women and Children Health, Wenzhou, Zhejiang, China

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Xiaolu Shen Department of Gynecology and Obstetrics, Wenzhou People’s Hospital, Wenzhou Women and Children Health, Wenzhou, Zhejiang, China

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Xuanyu Chen Department of Gynecology and Obstetrics, Wenzhou People’s Hospital, Wenzhou Women and Children Health, Wenzhou, Zhejiang, China

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Jieqiang Lv Department of Gynecology and Obstetrics, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China

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Songying Zhang Department of Obstetrics and Gynecology, Assisted Reproduction Unit, Sir Run Run ShawHospital, Zhejiang University School of Medicine Key Laboratory of Reproductive Dysfunction Management of Zhejiang Province, Hangzhou, Zhejiang, China

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that testosterone induced the ER stress status in β cells. Figure 2 TE-induced ER stress in INS-1 cells and primary cultured mouse islets. Levels of XBP1(S), CHOP and DR5 mRNA in INS-1 cells (A) and primary cultured mouse islets (B) were measured

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0608
Volume/Issue:
Volume 10: Issue 3
Open access
Wei Li Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China

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Qing Huang Collage of Tourism and Service Management, Nankai University, Tianjin, People’s Republic of China

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Danyang Sun Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China

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Guizhi Zhang Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China

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Jian Tan Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China

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Western blot was reduced in RDM1 -siRNA infected cells, indicating effective knockdown of the target sequence ( Fig. 3B ). Compared with cells infected with control lentivirus shCtrl, the RDM1 mRNA expression in cells infected with shRDM1 was lower

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0209
Volume/Issue:
Volume 6: Issue 8
Open access
Athanasios D Anastasilakis Department of Endocrinology, 424 General Military Hospital, Thessaloniki, Greece

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Marina Tsoli 1st Propaedeutic Department of Internal Medicine, National and Kapodistrian University of Athens, Athens, Greece

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Gregory Kaltsas 1st Propaedeutic Department of Internal Medicine, National and Kapodistrian University of Athens, Athens, Greece

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Polyzois Makras Department of Endocrinology and Diabetes, 251 Hellenic Air Force & VA General Hospital, Athens, Greece

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oncogene homolog B (BRAF) mutations in LCH lesions point toward a neoplastic rather than an inflammatory nature of the disease ( 1 , 10 ). A combining hypothesis considers LCH to be an inflammatory neoplasia as LCH cells harboring oncogenic mutations

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-18-0186
Volume/Issue:
Volume 7: Issue 7
Open access
Serena Martinelli Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy

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Mario Maggi Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy

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Elena Rapizzi Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy

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spheroids is the excellent proven suitability of this model for drug screenings ( 38 , 39 ). Figure 1 Cluster and spheroid formation. (A) Representative image of MTT cells that spontaneously form clusters when cultured in monolayer. (B) Induction of

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-20-0472
Volume/Issue:
Volume 9: Issue 12
Open access
Ping Gu Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

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Yuege Lin Department of Pathology, Nanjing Medical University, Nanjing, China

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Qi Wan Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

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Dongming Su Department of Pathology, Nanjing Medical University, Nanjing, China

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Qun Shu Department of Obstetrics, Shanghai First Maternity and Infant Health Hospital, School of Medicine, Tongji University, Shanghai, China

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released glucose-stimulated c-peptide ( Fig. 1B ) and between the serum oxytocin levels and the HOMA-β index ( Fig. 1C ). Figure 1 Decreased serum oxytocin levels are associated with β-cell dysfunction in patients with gestational diabetes mellitus

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0043
Volume/Issue:
Volume 10: Issue 7
Open access
Stavroula Stavrou Department of Gynecology and Obstetrics, Hospital of the LMU, Munich, Germany

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Michael Gratz Department of Gynecology and Obstetrics, Hospital of the LMU, Munich, Germany

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Eileen Tremmel Department of Gynecology and Obstetrics, Hospital of the LMU, Munich, Germany

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Christina Kuhn Department of Gynecology and Obstetrics, Hospital of the LMU, Munich, Germany

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Simone Hofmann Department of Gynecology and Obstetrics, Hospital of the LMU, Munich, Germany

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Helene Heidegger Department of Gynecology and Obstetrics, Hospital of the LMU, Munich, Germany

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Mina Peryanova Department of Gynecology and Obstetrics, Hospital of the LMU, Munich, Germany

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Kerstin Hermelink Department of Gynecology and Obstetrics, Hospital of the LMU, Munich, Germany

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Stefan Hutter Department of Gynecology and Obstetrics, Hospital of the LMU, Munich, Germany

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Bettina Toth Department of Gynaecological Endocrinology and Reproductive Medicine, Medical University Innsbruck, Innsbruck, Austria

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Doris Mayr Department of Pathology, Hospital of the LMU, Munich, Germany

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Sven Mahner Department of Gynecology and Obstetrics, Hospital of the LMU, Munich, Germany

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Udo Jeschke Department of Gynecology and Obstetrics, Hospital of the LMU, Munich, Germany

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Aurelia Vattai Department of Gynecology and Obstetrics, Hospital of the LMU, Munich, Germany

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 = 0.007). (B) Picture of Western blot membrane of BeWo cells where (A). BeWo cell control group. (B) BeWo cells stimulated with 10 nM T 1 AM. ODC protein expression in BeWo trophoblast model cells after stimulation with T 3 BeWo

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0272
Volume/Issue:
Volume 7: Issue 2
Open access