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population. Participants that had thyroid ultrasound results and complete clinical data were included in this study. The exclusion criteria included a history of thyroid disease other than TN, a history of radiotherapy or surgery on the head and neck, a
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The University of Liverpool, Brownlow Hill, Liverpool, UK
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causes of hypopituitarism, e.g. radiotherapy, surgery, pituitary adenoma, hypophysitis is well recognized as a cause of isolated ACTH deficiency that may present as acute cortisol deficiency and should be treated as described elsewhere in this document
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(Basel) 2022 511 . ( https://doi.org/10.3390/life12040511 ) 20 Izard MA . Leydig cell function and radiation: a review of the literature . Radiotherapy and Oncology 1995 34 1 – 8 . ( https://doi.org/10.1016/0167-8140(9401501-S ) 21 Nies M Arts
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neurosurgery, medical therapy and radiotherapy can be needed to treat pituitary adenomas ( 4 , 5 , 6 , 7 ). There is an increased likelihood of aggressive pituitary adenoma characteristics (early age at diagnosis, large tumor size, increased invasiveness
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– PRRT 11 12 Chemotherapy 6 2 Everolimus 1 N/A Loco-regional (liver) 6 3 Radiotherapy 3 N/A Chemotherapy, FOLFOX, or paclitaxel + cisplatin, or etoposide + cisplatin; loco-regional therapy for
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agents – mainly cisplatin, doxorubicin, etoposide; or mitotane associated with these agents) and only three patients received radiotherapy (doses were not available). Fourteen patients died (all deaths were related to ACT complications), 16 lost follow
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, plasma-free normetanephrins; PHPT, primary hyperparathyroidism; RT, radiotherapy; SC, synchoronous; TTx, total thyroidectomy; U/L, unilateral; UNMN, 24 h urinary normetanephrines; UMN, 24 h urinary metanephrins; UE, 24 h urinary epinephrines; UNE, 24 h
Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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with chemotherapy, and 61.0% (25/40) received cranial radiotherapy. Concomitant comorbidities observed in the investigated COGHD cohort in TP are presented in Table 2 . Figure 1 Study cohort flow chart. Table 1 Distribution of
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was shown that intermittent administration of PTH can prevent osteocyte apoptosis caused by glucocorticoid excess ( 116 ) or radiotherapy ( 117 ). Vitamin D was also found to affect the viability and characteristics of osteocytes. Namely, vitamin D
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, 84 , 85 ). Additionally, radiotherapy significantly improved the visual functioning aspect of GO-QoL, while eyelid lengthening and blepharoplasty significantly improved the appearance-related aspect of GO-QoL ( 17 , 83 ). Steroid treatment was also