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Vito Francic Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria

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Martin Keppel Department of Laboratory Medicine, Paracelsus Medical University, Salzburg, Austria

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Verena Schwetz Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria

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Christian Trummer Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria

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Marlene Pandis Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria

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Valentin Borzan Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria

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Martin R Grübler Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria

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Nicolas D Verheyen Division of Cardiology, Department of Internal Medicine, Medical University of Graz, Graz, Austria

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Marcus E Kleber Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany

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Graciela Delgado Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany

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Angela P Moissl Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany

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Benjamin Dieplinger Department of Laboratory Medicine, Konventhospital Barmherzige Brueder Linz, Linz, Austria

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Winfried März Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany
Synlab Academy, Synlab Holding Germany GmbH, Heidelberg, Germany

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Andreas Tomaschitz Specialist Clinic of Rehabilitation Bad Gleichenberg, Bad Gleichenberg, Austria

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Stefan Pilz Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria

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Barbara Obermayer-Pietsch Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria

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size of 0.5, for a two-sided alternative hypothesis with an α of 0.05 and a power of 90%. Further details can be found in the publication of the original study ( 23 ). Recruitment took place from June 2011 to August 2014 and 200 Caucasian study

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0090
Volume/Issue:
Volume 8: Issue 6
Open access
Dmitry M Davydov Laboratory of Neuroimmunopathology, Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia

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Malik K Nurbekov Laboratory of Sociogenomics, Moscow State Pedagogical University, Moscow, Russia

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power = 0.80 with β = 0.60, dominant allele frequency = 0.54 and mean ( s.d .) of FPG = 5.3 (0.7) mmol/L obtained from a previous study and accepted for a group of subjects without diabetes ( 39 ). Additional 43 subjects were included in the patient

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-16-0009
Volume/Issue:
Volume 5: Issue 2
Open access
Anna Malczewska Department of Endocrinology and Neuroendocrine Tumours, Medical University of Silesia, Katowice, Poland

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Kjell Oberg Department of Endocrine Oncology, University Hospital, Uppsala, Sweden

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Beata Kos-Kudla Department of Endocrinology and Neuroendocrine Tumours, Medical University of Silesia, Katowice, Poland

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score cut-off: 20. Statistical analysis The sample size needed to detect significant differences in CgA levels per assay (from previously published mean ± s.e.m. , using a power of 0.8 and α = 0.05) was calculated to be a minimum of 210

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0417
Volume/Issue:
Volume 10: Issue 1
Open access
Angelica Lindén Hirschberg Division of Obstetrics and Gynaecology, Department of Women’s and Children’s Health, Karolinska Institutet, Stockholm, Sweden
Department of Gynecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden.

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IGF ( 43 ), all of which may enhance skeletal muscular activity. Obviously, muscle growth and the accompanying increase in strength and power could enhance performance. In addition, bone formation is stimulated by androgens, both directly and in part

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-19-0537
Volume/Issue:
Volume 9: Issue 4
Open access
T Grimmichova Institute of Endocrinology, Narodni, Prague, Czech Republic
2nd Department of Internal Medicine, University Hospital Kralovske Vinohrady and Third Faculty of Medicine, Charles University in Prague, Srobarova, Prague, Czech Republic

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M Haluzik Institute of Endocrinology, Narodni, Prague, Czech Republic
Diabetes Centre, Institute for Clinical and Experimental Medicine (IKEM), Videnska, Prague, Czech Republic

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K Vondra Institute of Endocrinology, Narodni, Prague, Czech Republic

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P Matucha Institute of Endocrinology, Narodni, Prague, Czech Republic

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M Hill Institute of Endocrinology, Narodni, Prague, Czech Republic

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iodine sufficiency ( 15 ). The power of the sample size was established. The patients were recruited from October 2013 to February 2018. Patient history, ultrasound of neck (US), and biochemical testing were done at the Institute of Endocrinology and 2nd

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0180
Volume/Issue:
Volume 9: Issue 7
Open access
Chiara Jongerius Amsterdam UMC, Location AMC, Medical Psychology, Amsterdam, The Netherlands
Amsterdam Public Health, Quality of Care, Amsterdam, The Netherlands

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Marij A Hillen Amsterdam UMC, Location AMC, Medical Psychology, Amsterdam, The Netherlands
Amsterdam Public Health, Quality of Care, Amsterdam, The Netherlands

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Ellen M A Smets Amsterdam UMC, Location AMC, Medical Psychology, Amsterdam, The Netherlands
Amsterdam Public Health, Quality of Care, Amsterdam, The Netherlands

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Mathijs J Mol Amsterdam UMC, Location AMC, Medical Psychology, Amsterdam, The Netherlands

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Eefje S Kooij Amsterdam UMC, Location AMC, Medical Psychology, Amsterdam, The Netherlands

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Maria A de Nood Amsterdam UMC, Location AMC, Medical Psychology, Amsterdam, The Netherlands

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Edwin S Dalmaijer MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, United Kingdom

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Eric Fliers Department of Endocrinology & Metabolism, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, Location AMC, Amsterdam, The Netherlands

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Johannes A Romijn Department of Medicine, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, Location AMC, Amsterdam, The Netherlands

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Daniel S Quintana University of Oslo, Department of Psychology, Oslo, Norway
Department of Rare Disorders and Disabilities, Oslo University Hospital, NevSom, Oslo, Norway
University of Oslo, Norwegian Centre for Mental Disorders Research (NORMENT) and KG Jebsen Centre for Neurodevelopmental Disorders, Oslo, Norway

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inflation in published studies ( 55 ), we powered our study to detect a smaller effect size, two-tailed α of 0.05, with 80% statistical power. Data cleaning was done in SPSS for Windows, version 24.0 (SPSS Inc. 26 ed., 2020). We excluded missing data

Article Type:
Research Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-22-0377
Volume/Issue:
Volume 12: Issue 8
Open access
Lára Ósk Eggertsdóttir Claessen Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland
Department of Emergency Medicine, Landspitali – The National University Hospital of Iceland, Reykjavik, Iceland

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Hafrún Kristjánsdóttir Physical Activity, Physical Education, Sport, and Health (PAPESH) Research Centre, Sports Science Department, School of Social Sciences, Reykjavik University, Reykjavik, Iceland

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María Kristín Jónsdóttir Mental Health Services, Landspitali – The National University Hospital of Iceland, Reykjavik, Iceland
Department of Psychology, School of Social Sciences, Reykjavik University, Reykjavik, Iceland

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Sigrún Helga Lund deCODE Genetics, Inc/Amgen Inc., Reykjavik, Iceland
School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland

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Ingunn Unnsteinsdóttir Kristensen Department of Psychology, School of Social Sciences, Reykjavik University, Reykjavik, Iceland

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Helga Ágústa Sigurjónsdóttir Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland
Department of Medicine, Landspitali – The National University Hospital of Iceland, Reykjavik, Iceland

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for 80% power was calculated using Lehr’s formula. Table 2 Demographic and clinical characteristics of the study population. Women with pituitary dysfunction were compared to women with normal pituitary to identify possible risk factors for

Article Type:
Research Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-23-0363
Volume/Issue:
Volume 13: Issue 2
Open access
Elizabeth J de Koster Department of Radiology and Nuclear Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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Olga Husson Department of Psychosocial Research and Epidemiology, Netherlands Cancer Institute, Amsterdam, The Netherlands
Division of Medical Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands
Division of Clinical Studies, Institute of Cancer Research, London, UK

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Eveline W C M van Dam Department of Internal Medicine, Division of Endocrinology, location VU University Medical Center, Amsterdam University Medical Centers, Amsterdam, The Netherlands

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G Sophie Mijnhout Department of Internal Medicine, Isala Hospital, Zwolle, The Netherlands

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Romana T Netea-Maier Department of Internal Medicine, Division of Endocrinology, Radboud University Medical Centre, Nijmegen, The Netherlands

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Wim J G Oyen Department of Radiology and Nuclear Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
Department of Radiology and Nuclear Medicine, Rijnstate Hospital, Arnhem, The Netherlands
Department of Biomedical Sciences and Humanitas Clinical and Research Centre, Department of Nuclear Medicine, Humanitas University, Milan, Italy

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Marieke Snel Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands

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Lioe-Fee de Geus-Oei Department of Radiology and Nuclear Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
Department of Radiology, Section of Nuclear Medicine, Leiden University Medical Center, Leiden, The Netherlands
Biomedical Photonic Imaging Group, University of Twente, Enschede, The Netherlands

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Dennis Vriens Department of Radiology, Section of Nuclear Medicine, Leiden University Medical Center, Leiden, The Netherlands

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for the EfFECTS trial study group
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acquired during a randomised controlled trial, the study was not a priori powered to distinguish HRQoL effects ( 6 ). Post hoc sensitivity analysis, however, showed that in the smallest cohort (i.e. active surveillance group, n  = 23) we have 80% power

Article Type:
Research Article
Collections:
Thyroid
DOI:
https://doi.org/10.1530/EC-22-0014
Volume/Issue:
Volume 11: Issue 8
Open access
Marta Fichna Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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Piotr P Małecki Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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Magdalena Żurawek Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland

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Katarzyna Furman Ludwik Perzyna Regional Hospital, Kalisz, Poland

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Bolesław Gębarski Regional Outpatient Medical Centre, Katowice, Poland

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Piotr Fichna Department of Paediatric Diabetes and Obesity, Poznan University of Medical Sciences, Poznan, Poland

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Marek Ruchała Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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-squaretest was used for association analyses on 2 × 2 and 2 × 3 contingency tables. Two-tailed P values <0.05 were considered statistically significant. The power of the study was evaluated by means of the online PS power and sample size calculator v.2

Article Type:
Research Article
Collections:
Adrenal
DOI:
https://doi.org/10.1530/EC-23-0008
Volume/Issue:
Volume 12: Issue 6
Open access
Danielle Christine Maria van der Kaay Erasmus University Medical Center, Department of Pediatrics, Subdivision of Endocrinology, Rotterdam, Netherlands

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Anne Rochtus Department of Pediatric Endocrinology, University Hospitals Leuven, Leuven, Belgium

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Gerhard Binder University Children’s Hospital, Pediatric Endocrinology, University of Tübingen, Tübingen, Germany

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Ingo Kurth Institute of Human Genetics, Medical Faculty, RWTH Aachen University, Aachen, Germany

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Dirk Prawitt Center for Paediatrics and Adolescent Medicine, University Medical Center, Mainz, Germany

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Irène Netchine Sorbonne Université, Centre de Recherche Saint-Antoine, INSERM, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France

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Gudmundur Johannsson Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Department of Endocrinology at Sahlgrenska University Hospital, Gothenburg, Sweden

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Anita C S Hokken-Koelega Erasmus University Medical Center, Department of Pediatrics, Subdivision of Endocrinology, Rotterdam, Netherlands

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Miriam Elbracht Institute of Human Genetics, Medical Faculty, RWTH Aachen University, Aachen, Germany

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Thomas Eggermann Institute of Human Genetics, Medical Faculty, RWTH Aachen University, Aachen, Germany

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and the public health issues (‘when to test what’). In this review, we illustrate the power of current and future comprehensive molecular genetic strategies for an accurate and personalized diagnosis and assess their appropriate use. Clinical

Article Type:
Review Article
Collections:
Paediatric Endocrinology
DOI:
https://doi.org/10.1530/EC-22-0277
Volume/Issue:
Volume 11: Issue 11
Open access